Search Results - "CLARK FILES, D."

Intramyocellular Lipid and Impaired Myofiber Contraction in Normal Weight and Obese Older Adults by Choi, Seung J, Files, D Clark, Zhang, Tan, Wang, Zhong-Min, Messi, Maria L, Gregory, Heather, Stone, John, Lyles, Mary F, Dhar, Sanjay, Marsh, Anthony P, Nicklas, Barbara J, Delbono, Osvaldo

“…Evidence implicates the amount and location of fat in aging-related loss of muscle function; however, whether intramyocellular lipids affect muscle contractile…”
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Physical Function Trajectories in Survivors of Acute Respiratory Failure by Gandotra, Sheetal, Lovato, James, Case, Douglas, Bakhru, Rita N, Gibbs, Kevin, Berry, Michael, Files, D Clark, Morris, Peter E

“…Survivorship from critical illness has improved; however, factors mediating the functional recovery of persons experiencing a critical illness remain…”
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The sympathetic nervous system regulates skeletal muscle motor innervation and acetylcholine receptor stability by Rodrigues, Anna C. Z., Messi, Maria L., Wang, Zhong‐Min, Abba, Martin C., Pereyra, Andrea, Birbrair, Alexander, Zhang, Tan, O’Meara, Meaghan, Kwan, Ping, Lopez, Elsa I. S., Willis, Monte S., Mintz, Akiva, Files, D. Clark, Furdui, Cristina, Oppenheim, Ronald W., Delbono, Osvaldo

“…Aim Symptoms of autonomic failure are frequently the presentation of advanced age and neurodegenerative diseases that impair adaptation to common physiologic…”
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Physical function impairment in survivors of critical illness in an ICU Recovery Clinic by Bakhru, Rita N., Davidson, James F., Bookstaver, Rebecca E., Kenes, Michael T., Welborn, Kristin G., Morris, Peter E., Clark Files, D.

“…The aims were to 1) determine feasibility of measuring physical function in our ICU Recovery Clinic (RC), 2) determine if physical function was associated with…”
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Quantitative peripheral muscle ultrasound in sepsis: Muscle area superior to thickness by Palakshappa, Jessica A., Reilly, John P., Schweickert, William D., Anderson, Brian J., Khoury, Viviane, Shashaty, Michael G., Fitzgerald, David, Forker, Caitlin, Butler, Kelly, Ittner, Caroline A., Feng, Rui, Files, D. Clark, Bonk, Michael P., Christie, Jason D., Meyer, Nuala J.

“…The objective of this study is to describe the relationship between two quantitative muscle ultrasound measures, the rectus femoris cross-sectional area…”
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A conceptual framework: the early and late phases of skeletal muscle dysfunction in the acute respiratory distress syndrome by Files, D Clark, Sanchez, Michael A, Morris, Peter E

“…Patients with acute respiratory distress syndrome (ARDS) often develop severe diaphragmatic and limb skeletal muscle dysfunction. Impaired muscle function in…”
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Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness by Heyland, Daren K, Day, Andrew, Clarke, G John, Hough, Catherine (Terri), Files, D Clark, Mourtzakis, Marina, Deutz, Nicolaas, Needham, Dale M, Stapleton, Renee

“…IntroductionSurvivors of critical illness often experience significant morbidities, including muscle weakness and impairments in physical functioning. This…”
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Association of early sedation level with patient outcomes in moderate-to-severe acute respiratory distress syndrome: Propensity-score matched analysis by Palakshappa, Jessica A., Russell, Gregory B., Gibbs, Kevin W., Kloefkorn, Chad, Hayden, Douglas, Moss, Marc, Hough, Catherine L., Files, D. Clark

“…Studies of early depth of sedation in mixed critically ill populations have suggested benefit to light sedation; however, the relationship of early depth of…”
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A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure by Langley, Raymond J., Migaud, Marie E., Flores, Lori, Thompson, J. Will, Kean, Elizabeth A., Mostellar, Murphy M., Mowry, Matthew, Luckett, Patrick, Purcell, Lina D., Lovato, James, Gandotra, Sheetal, Benton, Ryan, Files, D. Clark, Harrod, Kevin S., Gillespie, Mark N., Morris, Peter E.

“…Acute respiratory failure (ARF) requiring mechanical ventilation, a complicating factor in sepsis and other disorders, is associated with high morbidity and…”
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Associations between persistent symptoms after mild COVID‐19 and long‐term health status, quality of life, and psychological distress by Han, Jin H., Womack, Kelsey N., Tenforde, Mark W., Files, D. Clark, Gibbs, Kevin W., Shapiro, Nathan I., Prekker, Matthew E., Erickson, Heidi L., Steingrub, Jay S., Qadir, Nida, Khan, Akram, Hough, Catherine L., Johnson, Nicholas J., Ely, E. Wesley, Rice, Todd W., Casey, Jonathan D., Lindsell, Christopher J., Gong, Michelle N., Srinivasan, Vasisht, Lewis, Nathaniel M., Patel, Manish M., Self, Wesley H.

“…Background We sought to assess whether persistent COVID‐19 symptoms beyond 6 months (Long‐COVID) among patients with mild COVID‐19 is associated with poorer…”
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Influence of Prehospital Function and Strength on Outcomes of Critically Ill Older Adults by Files, D. Clark, Neiberg, Rebecca, Rushing, Julia, Morris, Peter E., Young, Michael P., Ayonayon, Hilsa, Harris, Tamara, Newman, Anne, Rubin, Susan, Shiroma, Eric, Houston, Denise, Miller, Michael E., Kritchevsky, Stephen B.

“…Objectives To understand the influence of prehospital physical function and strength on clinical outcomes of critically ill older adults. Design Secondary…”
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Activated mast cells in skeletal muscle can be a potential mediator for cancer‐associated cachexia by Widner, D. Brooke, Liu, Chun, Zhao, Qingxia, Sharp, Sarah, Eber, Matthew R., Park, Sun H., Files, D. Clark, Shiozawa, Yusuke

“…Background Eighty per cent of United States advanced cancer patients faces a worsened prognosis due to cancer‐associated cachexia. Inflammation is one driver…”
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Influenza vaccine acceptance and hesitancy among adults hospitalized with severe acute respiratory illnesses, United States 2019–2020 by Lytle, Kelsey L., Collins, Sean P., Feldstein, Leora R., Baughman, Adrienne H., Brown, Samuel M., Casey, Jonathan D., Erickson, Heidi L., Exline, Matthew C., Files, D. Clark, Gibbs, Kevin W., Ginde, Adit A., Gong, Michelle N., Grijalva, Carlos G., Khan, Akram, Lindsell, Christopher J., Peltan, Ithan D., Prekker, Matthew E., Rice, Todd W., Shapiro, Nathan I., Steingrub, Jay S., Stubblefield, William B., Tenforde, Mark W., Womack, Kelsey N., Patel, Manish M., Self, Wesley H.

“…•Among 679 severely ill adults during the 2019–2020 influenza season, 38.9% were unvaccinated.•Among those unvaccinated, 51.1% reported intentionally avoiding…”
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Characteristics of Adult Outpatients and Inpatients with COVID-19 - 11 Academic Medical Centers, United States, March-May 2020 by Tenforde, Mark W, Billig Rose, Erica, Lindsell, Christopher J, Shapiro, Nathan I, Files, D Clark, Gibbs, Kevin W, Prekker, Matthew E, Steingrub, Jay S, Smithline, Howard A, Gong, Michelle N, Aboodi, Michael S, Exline, Matthew C, Henning, Daniel J, Wilson, Jennifer G, Khan, Akram, Qadir, Nida, Stubblefield, William B, Patel, Manish M, Self, Wesley H, Feldstein, Leora R

“…Descriptions of coronavirus disease 2019 (COVID-19) in the United States have focused primarily on hospitalized patients. Reports documenting exposures to…”
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Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting by Files, D Clark, Liu, Chun, Pereyra, Andrea, Wang, Zhong-Min, Aggarwal, Neil R, D'Alessio, Franco R, Garibaldi, Brian T, Mock, Jason R, Singer, Benjamin D, Feng, Xin, Yammani, Raghunatha R, Zhang, Tan, Lee, Amy L, Philpott, Sydney, Lussier, Stephanie, Purcell, Lina, Chou, Jeff, Seeds, Michael, King, Landon S, Morris, Peter E, Delbono, Osvaldo

“…Early mobilization of critically ill patients with the acute respiratory distress syndrome (ARDS) has emerged as a therapeutic strategy that improves patient…”
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The relationship between self-report and performance-based measures of physical function following an ICU stay by Berry, Michael J., Love, Nathan J., Files, D. Clark, Bakhru, Rita N., Morris, Peter E.

“…To examine relationships between self-report and performance-based measures of physical function in ICU patients randomized to standardized rehabilitation…”
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Skeletal Muscle Myofibers Directly Contribute to LPS-Induced Systemic Inflammatory Tone by Bivona Iii, Joseph J, Mank, Madeleine M, Stapleton, Renee D, Files, D Clark, Toth, Michael J, Poynter, Matthew E

“…The abundance, anatomical distribution, and vascularity of skeletal muscle make it a potentially important contributor to local cytokine production and…”
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Modeling the Impacts of Clinical Influenza Testing on Influenza Vaccine Effectiveness Estimates by Feldstein, Leora R, Ferdinands, Jill M, Self, Wesley H, Randolph, Adrienne G, Aboodi, Michael, Baughman, Adrienne H, Brown, Samuel M, Exline, Matthew C, Clark Files, D, Gibbs, Kevin, Ginde, Adit A, Gong, Michelle N, Grijalva, Carlos G, Halasa, Natasha, Khan, Akram, Lindsell, Christopher J, Newhams, Margaret, Peltan, Ithan D, Prekker, Matthew E, Rice, Todd W, Shapiro, Nathan I, Steingrub, Jay, Talbot, H Keipp, Halloran, M Elizabeth, Patel, Manish

“…Abstract Background Test-negative design studies for evaluating influenza vaccine effectiveness (VE) enroll patients with acute respiratory infection…”
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A Critical Role for Muscle Ring Finger-1 in Acute Lung Injury-associated Skeletal Muscle Wasting by CLARK FILES, D, D'ALESSIO, Franco R, WILLIS, Monte S, PATTERSON, Cam, TANKERSLEY, Clarke G, MESSI, Maria L, CHUN LIU, DELBONO, Osvaldo, DAVID FURLOW, J, BODINE, Sue C, COHN, Ronald D, KING, Landon S, JOHNSTON, Laura F, CROW, Michael T, KESARI, Priya, AGGARWAL, Neil R, GARIBALDI, Brian T, MOCK, Jason R, SIMMERS, Jessica L, DEGORORDO, Antonio, MURDOCH, Jared

“…Acute lung injury (ALI) is a debilitating condition associated with severe skeletal muscle weakness that persists in humans long after lung injury has…”
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Macrophages modulate skeletal muscle wasting and recovery in acute lung injury in mice by Krall, Jennifer T. W., Belfield, Lanazha, Strysick, Claire, Liu, Chun, Purcell, Lina, Stapleton, Renee, Toth, Michael, Poynter, Matthew, Zhu, Xuewei, Gibbs, Kevin, Files, D. Clark

“…Skeletal muscle dysfunction in critical illnesses leaves survivors weak and functionally impaired. Macrophages infiltrate muscles; however, their functional…”
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