Search Results - "CLAESSON, J."
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Comparing Apples and Oranges?: Next Generation Sequencing and Its Impact on Microbiome Analysis
Published in PloS one (05-02-2016)“…Rapid advancements in sequencing technologies along with falling costs present widespread opportunities for microbiome studies across a vast and diverse array…”
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Gut microbiome, big data and machine learning to promote precision medicine for cancer
Published in Nature reviews. Gastroenterology & hepatology (01-10-2020)“…The gut microbiome has been implicated in cancer in several ways, as specific microbial signatures are known to promote cancer development and influence…”
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Diversity of bifidobacteria within the infant gut microbiota
Published in PloS one (11-05-2012)“…The human gastrointestinal tract (GIT) represents one of the most densely populated microbial ecosystems studied to date. Although this microbial consortium…”
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16S rRNA gene sequencing of mock microbial populations- impact of DNA extraction method, primer choice and sequencing platform
Published in BMC microbiology (24-06-2016)“…Next-generation sequencing platforms have revolutionised our ability to investigate the microbiota composition of complex environments, frequently through 16S…”
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Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine
Published in PloS one (20-08-2009)“…Variations in the composition of the human intestinal microbiota are linked to diverse health conditions. High-throughput molecular technologies have recently…”
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Regulation of prefrontal cortex myelination by the microbiota
Published in Translational psychiatry (05-04-2016)“…The prefrontal cortex (PFC) is a key region implicated in a range of neuropsychiatric disorders such as depression, schizophrenia and autism. In parallel, the…”
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Comparison of two next-generation sequencing technologies for resolving highly complex microbiota composition using tandem variable 16S rRNA gene regions
Published in Nucleic acids research (01-12-2010)“…High-throughput molecular technologies can profile microbial communities at high resolution even in complex environments like the intestinal microbiota. Recent…”
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Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment
Published in Frontiers in microbiology (19-02-2021)“…The number of microbiome-related studies has notably increased the availability of data on human microbiome composition and function. These studies provide the…”
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Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
Published in Nature communications (23-03-2020)“…Studies of inflammatory bowel disease (IBD) have been inconclusive in relating microbiota with distribution of inflammation. We report microbiota, host…”
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Categorization of the gut microbiota: enterotypes or gradients?
Published in Nature reviews. Microbiology (01-09-2012)“…Grouping the microbiota of individual subjects into compositional categories, or enterotypes, based on the dominance of certain genera may have oversimplified…”
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Composition, variability, and temporal stability of the intestinal microbiota of the elderly
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-2011)“…Alterations in the human intestinal microbiota are linked to conditions including inflammatory bowel disease, irritable bowel syndrome, and obesity. The…”
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A comparison of the gut microbiome between long‐term users and non‐users of proton pump inhibitors
Published in Alimentary pharmacology & therapeutics (01-05-2016)“…Summary Background Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is…”
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Piphillin predicts metagenomic composition and dynamics from DADA2-corrected 16S rDNA sequences
Published in BMC genomics (17-01-2020)“…Shotgun metagenomic sequencing reveals the potential in microbial communities. However, lower-cost 16S ribosomal RNA (rRNA) gene sequencing provides taxonomic,…”
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Esophageal microbiome in active eosinophilic esophagitis and changes induced by different therapies
Published in Scientific reports (29-03-2021)“…Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory esophageal disease triggered by food antigens. Cumulative evidence supports the…”
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Strain-Level Metagenomic Analysis of the Fermented Dairy Beverage Nunu Highlights Potential Food Safety Risks
Published in Applied and environmental microbiology (15-08-2017)“…The rapid detection of pathogenic strains in food products is essential for the prevention of disease outbreaks. It has already been demonstrated that…”
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Sequence-Based Characterization of Intratumoral Bacteria-A Guide to Best Practice
Published in Frontiers in oncology (21-02-2020)“…Tumors are hospitable environments to bacteria and several recent studies on cancer patient samples have introduced the concept of an endogenous tumor…”
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Volatility as a Concept to Understand the Impact of Stress on the Microbiome
Published in Psychoneuroendocrinology (01-02-2021)“…•The gut microbiome is sensitive the effects of chronic stress.•We examined the stress-induced temporal effects on the composition of the microbiome, which we…”
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Diversity of bacteria populations associated with different thallus regions of the brown alga Laminaria digitata
Published in PloS one (25-11-2020)“…Stipitate kelp species such as Laminaria digitata dominate most cold-water subtidal rocky shores and form underwater forests which are among the most…”
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Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2011)“…Development of the human gut microbiota commences at birth, with bifidobacteria being among the first colonizers of the sterile newborn gastrointestinal tract…”
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Microbial Succession and Flavor Production in the Fermented Dairy Beverage Kefir
Published in mSystems (01-09-2016)“…Kefir is a putatively health-promoting dairy beverage that is produced when a kefir grain, consisting of a consortium of microorganisms, is added to milk to…”
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