Search Results - "CINGOLANI, Antonella"
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Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial
Published in Nature medicine (01-10-2021)“…Early increase of soluble urokinase plasminogen activator receptor (suPAR) serum levels is indicative of increased risk of progression of coronavirus disease…”
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Social media as a tool for scientific updating at the time of COVID pandemic: Results from a national survey in Italy
Published in PloS one (03-09-2020)“…In the face of the rapid evolution of the COVID-19 pandemic, healthcare professionals on the frontline are in urgent need of frequent updates in the…”
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Evidence gaps on weight gain in people living with HIV: a scoping review to define a research agenda
Published in BMC infectious diseases (14-04-2023)“…Combined antiretroviral therapy (cART) dramatically improved survival in people living with HIV (PLWH) but is associated with weight gain (WG), raising concern…”
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Risk of SARS-CoV-2 infection in patients with hematologic diseases receiving tixagevimab/cilgavimab as pre-exposure prophylaxis in most recent Omicron sublineages era
Published in International journal of infectious diseases (01-07-2024)“…•The 1-year incidence estimate of breakthrough infections (BTIs)/hospitalization/death was 24%.•A greater risk of incident BTIs was observed with BA.5 and…”
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First description of the katG gene deletion in a Mycobacterium tuberculosis clinical isolate and its impact on the mycobacterial fitness
Published in International journal of medical microbiology (01-05-2021)“…Isoniazid (INH) is the cornerstone of the anti-tuberculosis regimens and emergence of Mycobacterium tuberculosis (Mtb) resistant strains is a major threat to…”
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Does Syphilis Increase the Risk of HIV-RNA Elevation >200 Copies/mL in HIV-Positive Patients Under Effective Antiretroviral Treatment? Data From the ICONA Cohort
Published in Journal of acquired immune deficiency syndromes (1999) (01-10-2021)“…To assess the impact of syphilis infection on the risk of HIV-RNA elevation in people living with HIV (PLWH) with current HIV-RNA ≤50 copies/mL. The Italian…”
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Determinants of patient and health care services delays for tuberculosis diagnosis in Italy: a cross-sectional observational study
Published in BMC infectious diseases (20-12-2018)“…Prompt diagnosis of active tuberculosis (TB) has paramount importance to reduce TB morbidity and mortality and to prevent the spread of Mycobacterium…”
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Survival and predictors of death in people with HIV-associated lymphoma compared to those with a diagnosis of lymphoma in general population
Published in PloS one (31-10-2017)“…to compare overall survival in HIV-associated lymphoma (HIV-L) and lymphoma raising in HIV-negative population (nHIV-L) and to identify predictors of increased…”
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Persistent poor clinical outcomes of people living with HIV presenting with AIDS and late HIV diagnosis – results from the ICONA cohort in Italy, 2009-2022
Published in International journal of infectious diseases (01-05-2024)“…•A mortality gap remains for late presenters, particularly, AIDS presenters, in recent years.•Increased mortality for AIDS presenters was driven by AIDS events…”
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A machine-learning parsimonious multivariable predictive model of mortality risk in patients with Covid-19
Published in Scientific reports (27-10-2021)“…The COVID-19 pandemic is impressively challenging the healthcare system. Several prognostic models have been validated but few of them are implemented in daily…”
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Passive pre-exposure immunization by tixagevimab/cilgavimab in patients with hematological malignancy and COVID-19: matched-paired analysis in the EPICOVIDEHA registry
Published in Journal of hematology and oncology (01-04-2023)“…Only few studies have analyzed the efficacy of tixagevimab/cilgavimab to prevent severe Coronavirus disease 2019 (COVID-19) and related complications in…”
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Characteristic of IgA and IgG antibody response to SARS-CoV-2 infection in an Italian referral COVID-19 Hospital
Published in Internal and emergency medicine (01-01-2022)“…Introduction Antibody response plays a fundamental role in the natural history of infectious disease. A better understanding of the immune response in patients…”
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"Early transfusion of convalescent plasma in older patients with COVID-19 to prevent disease progression: A structured summary of a study protocol for a randomised controlled trial"
Published in Current controlled trials in cardiovascular medicine (22-10-2020)“…The primary objective is to demonstrate that COVID-19 convalescent plasma (CCP) prevents progression to severe pneumonia in elderly COVID-19 pneumonia patients…”
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Impact of HCV Eradication on Lipid Metabolism in HIV/HCV Coinfected Patients: Data from ICONA and HepaICONA Foundation Cohort Study
Published in Viruses (19-07-2021)“…Objectives: HCV shows complex interactions with lipid metabolism. Our aim was to examine total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C)…”
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Access and response to direct antiviral agents (DAA) in HIV-HCV co-infected patients in Italy: Data from the Icona cohort
Published in PloS one (17-05-2017)“…Real-life data on access and response to direct antiviral agents (DAA) in HIV-HCV coinfected individuals are lacking. HCV viremic, HIV-positive patients from…”
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COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1+ neutrophils and CD14+ monocytes
Published in JCI insight (08-07-2021)“…We explored the potential link between chronic inflammatory arthritis and COVID-19 pathogenic and resolving macrophage pathways and their role in COVID-19…”
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Real World Use of Tixagevimab/Cilgavimab Pre-Exposure Prophylaxis of COVID-19 in Immunocompromised Individuals: Data from the OCTOPUS Study
Published in Vaccines (Basel) (01-07-2024)“… We aimed to report the real-world use and outcomes over time in immunocompromised individuals receiving tixagevimab/cilgavimab (T/C) pre-exposure prophylaxis…”
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HIV Patients’ Tracer for Clinical Assistance and Research during the COVID-19 Epidemic (INTERFACE): A Paradigm for Chronic Conditions
Published in Information (Basel) (01-02-2022)“…The health emergency linked to the SARS-CoV-2 pandemic has highlighted problems in the health management of chronic patients due to their risk of infection,…”
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Reduced Rate of Diagnostic Positive Detection of JC Virus DNA in Cerebrospinal Fluid in Cases of Suspected Progressive Multifocal Leukoencephalopathy in the Era of Potent Antiretroviral Therapy
Published in Journal of Clinical Microbiology (01-08-2005)“…Fifty-nine human immunodeficiency virus (HIV)-infected patients with suspected progressive multifocal leukoencephalopathy and 224 controls were tested for JC…”
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