Search Results - "CIESLIK, A"

Ultra-sensitive CTC-based liquid biopsy for pancreatic cancer enabled by large blood volume analysis by Stoecklein, Nikolas H, Fluegen, Georg, Guglielmi, Rosa, Neves, Rui P L, Hackert, Thilo, Birgin, Emrullah, Cieslik, Stefan A, Sudarsanam, Monica, Driemel, Christiane, van Dalum, Guus, Franken, André, Niederacher, Dieter, Neubauer, Hans, Fehm, Tanja, Rox, Jutta M, Böhme, Petra, Häberle, Lena, Göring, Wolfgang, Esposito, Irene, Topp, Stefan A, Coumans, Frank A W, Weitz, Jürgen, Knoefel, Wolfram T, Fischer, Johannes C, Bork, Ulrich, Rahbari, Nuh N

“…The limited sensitivity of circulating tumor cell (CTC) detection in pancreatic adenocarcinoma (PDAC) stems from their extremely low concentration in the whole…”
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Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart by Cieslik, Katarzyna A, Taffet, George E, Carlson, Signe, Hermosillo, Jesus, Trial, JoAnn, Entman, Mark L

“…Abstract Diastolic dysfunction in the aging heart is a grave condition that challenges the life and lifestyle of a growing segment of our population. This…”
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Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels by Cieslik, Katarzyna A., Trial, JoAnn, Carlson, Signe, Taffet, George E., Entman, Mark L.

“…With age, the collagen content of the heart increases, leading to interstitial fibrosis. We have shown that CD44pos fibroblasts derived from aged murine hearts…”
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A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart by Angelini, Aude, Trial, JoAnn, Saltzman, Alexander B., Malovannaya, Anna, Cieslik, Katarzyna A.

“…The cardiac fibroblast interacts with an extracellular matrix (ECM), enabling myofibroblast maturation via a process called mechanosensing. Although in the…”
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3′UTR shortening of profibrotic genes and reversibility of fibrosis in patients with end‐stage right ventricular failure by Neupane, Rahul, Cieslik, Katarzyna A., Youker, Keith, Palaniyandi, Suresh Selvaraj, Guha, Ashrith, Thandavarayan, Rajarajan A.

“…Previous studies have shown 4HNE as a contributor to various pathologies such as LV hypertrophy, PH-induced RV fibrosis, remodelling, myocardial…”
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14-3-3ε Plays a Role in Cardiac Ventricular Compaction by Regulating the Cardiomyocyte Cell Cycle by Kosaka, Yasuhiro, Cieslik, Katarzyna A., Li, Ling, Lezin, George, Maguire, Colin T., Saijoh, Yukio, Toyo-oka, Kazuhito, Gambello, Michael J., Vatta, Matteo, Wynshaw-Boris, Anthony, Baldini, Antonio, Yost, H. Joseph, Brunelli, Luca

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Th1/M1 conversion to th2/m2 responses in models of inflammation lacking cell death stimulates maturation of monocyte precursors to fibroblasts by Trial, Joann, Cieslik, Katarzyna A, Haudek, Sandra B, Duerrschmid, Clemens, Entman, Mark L

“…We have demonstrated that cardiac fibrosis arises from the differentiation of monocyte-derived fibroblasts. We present here evidence that this process requires…”
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Mechanosensing dysregulation in the fibroblast: A hallmark of the aging heart by Angelini, Aude, Trial, JoAnn, Ortiz-Urbina, Jesus, Cieslik, Katarzyna A.

“…•Mechanosensing is the ability of a cell to respond to mechanical signals such as force or rigidity.•Fibroblasts transition into contractile myofibroblasts…”
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Radiolabelled 177Lu‐Bispidine‐Trastuzumab for Targeting Human Epidermal Growth Factor Receptor 2 Positive Cancers by Cieslik, Patrick A., Klingler, Simon, Nolff, Mirja, Holland, Jason P.

“…Radioimmunotherapy (RIT) is a promising alternative to conventional treatment options. Here, we present experimental work on the synthesis, radiochemistry, and…”
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Radiolabelled 177 Lu-Bispidine-Trastuzumab for Targeting Human Epidermal Growth Factor Receptor 2 Positive Cancers by Cieslik, Patrick A, Klingler, Simon, Nolff, Mirja, Holland, Jason P

“…Radioimmunotherapy (RIT) is a promising alternative to conventional treatment options. Here, we present experimental work on the synthesis, radiochemistry, and…”
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Meandering streams in a shallow fluid layer by Cieślik, A. R, Kamp, L. P. J, Clercx, H. J. H, van Heijst, G. J. F

“…Decaying turbulence in a shallow flow is shown to be characterized by the emergence of long-lived meandering currents, which are closely related to pronounced…”
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Defective Myofibroblast Formation from Mesenchymal Stem Cells in the Aging Murine Heart by Cieslik, Katarzyna A, Trial, JoAnn, Entman, Mark L

“…Aged mice in a murine model of myocardial infarction exhibit less effective myocardial repair. We hypothesized that the deficiency arises from altered lineage…”
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A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs by Cieslik, Katarzyna A.

“…[Display omitted]…”
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Dipole-wall collision in a shallow fluid by Cieślik, A.R., Akkermans, R.A.D., Kamp, L.P.J., Clercx, H.J.H., van Heijst, G.J.F.

“…Recent experiments on a freely evolving dipolar vortex in a homogeneous shallow fluid layer have clearly shown the importance of vertical secondary flows on…”
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Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis by Angelini, Aude, Ortiz-Urbina, Jesus, Trial, JoAnn, Reddy, Anilkumar K, Malovannaya, Anna, Jain, Antrix, Entman, Mark L, Taffet, George E, Cieslik, Katarzyna A

“…The incidence of diastolic dysfunction increases with age in both humans and mice. This is characterized by increased passive stiffness and slower relaxation…”
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Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart by Trial, JoAnn, Entman, Mark L, Cieslik, Katarzyna A

“…Abstract Pathologic fibrosis in the aging mouse heart is associated with dysregulated resident mesenchymal stem cells (MSC) arising from reduced stemness and…”
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Cleavage stimulating factor 64 depletion mitigates cardiac fibrosis through alternative polyadenylation by Neupane, Rahul, Youker, Keith, Yalamanchili, Hari Krishna, Cieslik, Katarzyna A., Karmouty-quintana, Harry, Guha, Ashrith, Thandavarayan, Rajarajan A.

“…Alternative polyadenylation (APA) regulates gene expression by cleavage and addition of poly(A) sequence at different polyadenylation sites (PAS) in 3′UTR,…”
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Aicar treatment reduces interstitial fibrosis in aging mice: Suppression of the inflammatory fibroblast by Cieslik, Katarzyna A, Trial, JoAnn, Entman, Mark L

“…In 2030, elderly people will represent 20% of the United States population. Even now, chronic cardiac diseases, especially heart failure with preserved…”
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Essential role of C-Rel in nitric-oxide synthase-2 transcriptional activation: time-dependent control by salicylate by Cieslik, Katarzyna A, Deng, Wu-Guo, Wu, Kenneth K

“…To determine the role of C-Rel in nitric-oxide synthase-2 (NOS-2) transcriptional activation, we evaluated the effect of lipopolysaccharide and…”
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The occurrence of the first two CTX-M-3 and TEM-1 producing isolates of Salmonella enterica serovar Oranienburg in Poland by Gierczyński, R, Szych, J, Cieślik, A, Rastawicki, W, Jagielski, M

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