Search Results - "CICLITIRA, P. J."

Review article: faecal transplantation therapy for gastrointestinal disease by Landy, J., Al‐Hassi, H. O., McLaughlin, S. D., Walker, A. W., Ciclitira, P. J., Nicholls, R. J., Clark, S. K., Hart, A. L.

“…Aliment Pharmacol Ther 2011; 34: 409–415 Summary Background  Evidence is emerging regarding the relationship between a dysbiosis of the human gut microbiota…”
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Review article: restorative proctocolectomy, indications, management of complications and follow‐up – a guide for gastroenterologists by MCLAUGHLIN, S. D., CLARK, S. K., TEKKIS, P. P., CICLITIRA, P. J., NICHOLLS, R. J.

“…Summary Background  Restorative proctocolectomy with ileal pouch‐anal anastomosis is the procedure of choice for the majority of patients with ulcerative…”
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Coeliac disease: in vivo toxicity of the putative immunodominant epitope by Fraser, J S, Engel, W, Ellis, H J, Moodie, S J, Pollock, E L, Wieser, H, Ciclitira, P J

“…Background: Peptides from α-gliadins have been used to characterise the immunodominant coeliac toxic epitope. A peptide corresponding to amino acid residues…”
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Pre-pouch ileitis: a disease of the ileum in ulcerative colitis after restorative proctocolectomy by Bell, A. J., Price, A. B., Forbes, A., Ciclitira, P. J., Groves, C., Nicholls, R. J.

“…Objective  Ileal inflammation in ulcerative colitis can occur as backwash ileitis or prestomal ileitis. After restorative proctocolectomy (RPC), ileal…”
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Extended spectrum beta‐lactamase‐producing bacteria and Clostridium difficile in patients with pouchitis by McLaughlin, S. D., Clark, S. K., Roberts, C. H., Perry‐Woodford, Z. L., Tekkis, P. P., Ciclitira, P. J., Nicholls, R. J.

“…Aliment Pharmacol Ther 2010; 32: 664–669 Summary Background  Treatment with fluoroquinolones is associated with the development of Clostridium difficile and…”
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An open study of antibiotics for the treatment of pre‐pouch ileitis following restorative proctocolectomy with ileal pouch–anal anastomosis by MCLAUGHLIN, S. D., CLARK, S. K., BELL, A. J., TEKKIS, P. P., CICLITIRA, P. J., NICHOLLS, R. J.

“…Summary Background  Pre‐pouch ileitis is a recently described condition which may occur following restorative proctocolectomy. Its aetiology remains unknown…”
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Constitutive gut-homing capacity on circulating myeloid dendritic cells in coeliac disease by Comino, I, Šuligoj, T, Al-Hassi, H O, Lee, G H, Sousa, C, Landy, J, Ciclitira, P J, Knight, S C, Bernardo, D

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Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis by Landy, J., Walker, A. W., Li, J. V., Al-Hassi, H. O., Ronde, E., English, N. R., Mann, E. R., Bernardo, D., McLaughlin, S. D., Parkhill, J., Ciclitira, P. J., Clark, S. K., Knight, S. C., Hart, A. L.

“…Faecal microbiota transplantation (FMT) is effective in the treatment of Clostridium difficile infection, where efficacy correlates with changes in microbiota…”
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Monoclonal antibody-based competitive assay for the sensitive detection of coeliac disease toxic prolamins by Bermudo Redondo, M.C., Griffin, P.B., Garzon Ransanz, M., Ellis, H.J., Ciclitira, P.J., O'Sullivan, C.K.

“…Current immunosorbent assays for gluten detection suffer from a number of drawbacks including lack of specificity (e.g. cross-reaction with coeliac disease…”
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Wheat peptide challenge in coeliac disease by Sturgess, R, Day, P, Ellis, H J, Lundin, K E, Gjertsen, H A, Kontakou, M, Ciclitira, P J

“…The exact nature of the cereal moiety that exacerbates coeliac disease is unknown. In-vitro studies have implicated both the N-terminal and far C-terminal…”
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Measurement of gluten using a monoclonal antibody to a coeliac toxic peptide of A gliadin by Ellis, H J, Rosen-Bronson, S, O’Reilly, N, Ciclitira, P J

“…Background—Future European Community regulations will require a sensitive and specific assay for measurement of coeliac toxic gluten proteins in foods marketed…”
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Review article: coeliac disease and its management by PARNELL, N. D. J, CICLITIRA, P. J

“…Coeliac disease (CD) is a disorder of the small intestine, characterized by villous atrophy, due to an intolerance to dietary gluten in genetically susceptible…”
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Investigation of the putative immunodominant T cell epitopes in coeliac disease by Ellis, H J, Pollock, E L, Engel, W, Fraser, J S, Rosen-Bronson, S, Wieser, H, Ciclitira, P J

“…Background: Coeliac disease (CD) is an enteropathy mediated by gluten specific T cells which secrete interferon γ (IFN-γ) when stimulated by gluten peptides…”
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Histological changes in small bowel mucosa induced by gliadin sensitive T lymphocytes can be blocked by anti-interferon gamma antibody by Przemioslo, R T, Lundin, K E, Sollid, L M, Nelufer, J, Ciclitira, P J

“…The isolation of gliadin specific HLA-DQ2 restricted T lymphocyte clones from the intestinal mucosa of patients with coeliac disease supports a role for cell…”
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Etiology of pouchitis by Landy, J., Al‐Hassi, H.O., McLaughlin, S.D., Knight, S.C., Ciclitira, P.J., Nicholls, R.J., Clark, S.K., Hart, A.L.

“…: Restorative proctocolectomy with ileal‐pouch anal anastomosis (RPC) is the operation of choice for ulcerative colitis (UC) patients requiring surgery. It is…”
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A genome-wide family-based linkage study of coeliac disease by KING, A. L., YIANNAKOU, J. Y., BRETT, P. M., CURTIS, D., MORRIS, M.-A., DEARLOVE, A. M., RHODES, M., ROSEN-BRONSON, S., MATHEW, C., ELLIS, H. J., CICLITIRA, P. J.

“…The susceptibility to develop coeliac disease (CD) has a strong genetic component, which is not entirely explained by HLA associations. Two previous genome…”
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Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole by Bell, A J G, Nicholls, R J, Forbes, A, Ellis, H J, Ciclitira, P J

“…Background/Aims: The gut flora may play an important role in the pathogenesis of inflammatory bowel disease. An ileal reservoir or pouch can be created to…”
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AGA Technical Review on Celiac Sprue by Ciclitira, Paul J.

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Towards a new gliadin reference material–isolation and characterisation by van Eckert, R., Berghofer, E., Ciclitira, P.J., Chirdo, F., Denery-Papini, S., Ellis, H.J., Ferranti, P., Goodwin, P., Immer, U., Mamone, G., Méndez, E., Mothes, T., Novalin, S., Osman, A., Rumbo, M., Stern, M., Thorell, L., Whim, A., Wieser, H.

“…Twenty-eight wheat cultivars representative of the three main European wheat producing countries, France, UK and Germany, were selected as a source for the…”
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Tissue transglutaminase antibodies in celiac disease by Biagi, F, Ellis, H J, Yiannakou, J Y, Brusco, G, Swift, G L, Smith, P M, Corazza, G R, Ciclitira, P J

“…Tissue transglutaminase is the antigen for antiendomysial antibodies, whose power in screening for celiac disease is well known. Our aim was to assess the…”
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