Search Results - "CIANFERANI, S"
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Maltaricin CPN, a new class IIa bacteriocin produced by Carnobacterium maltaromaticum CPN isolated from mould‐ripened cheese
Published in Journal of applied microbiology (01-11-2016)“…Aims The purpose of this study was to isolate, characterize and determine the structure and the antibacterial activities of a bacteriocin produced by…”
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Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies
Published in Journal of mass spectrometry. (01-02-2015)“…Antibodies represent a family of clinically relevant compounds with growing commercial potential. From a market perspective, their large size and structural…”
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A sulfenic acid enzyme intermediate is involved in the catalytic mechanism of peptide methionine sulfoxide reductase from Escherichia coli
Published in The Journal of biological chemistry (17-11-2000)“…Methionine oxidation into methionine sulfoxide is known to be involved in many pathologies and to exert regulatory effects on proteins. This oxidation can be…”
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VISLISI trial, a prospective clinical study allowing identification of a new metalloprotease and putative virulence factor from Staphylococcus lugdunensis
Published in Clinical microbiology and infection (01-05-2017)“…Staphylococcus lugdunensis is a coagulase-negative staphylococcus that displays an unusually high virulence rate close to that of Staphylococcus aureus. It…”
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Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas
Published in Leukemia (01-08-2013)Get full text
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Physical basis of the inducer-dependent cooperativity of the Central glycolytic genes Repressor/DNA complex
Published in Nucleic acids research (01-09-2010)“…The Central glycolytic genes Repressor (CggR) from Bacillus subtilis belongs to the SorC family of transcription factors that control major carbohydrate…”
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In situ characterization of polymorphic forms : The potential of Raman techniques
Published in Journal of thermal analysis and calorimetry (1999)Get full text
Conference Proceeding -
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Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage
Published in Nature communications (15-06-2020)“…Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimerʼs disease (AD). Here, we…”
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Vapor pressure and heat of sublimation of crystal polymorphs
Published in Journal of thermal analysis and calorimetry (1999)Get full text
Conference Proceeding -
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Investigating Ugi/Passerini Multicomponent Reactions for the Site‐Selective Conjugation of Native Trastuzumab
Published in Chemistry : a European journal (02-11-2020)“…Site‐selective modification of proteins has been the object of intense studies over the past decades, especially in the therapeutic field. Prominent results…”
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Functional insights from high resolution structures of mouse protein arginine methyltransferase 6
Published in Journal of structural biology (01-08-2015)“…PRMT6 is a protein arginine methyltransferase involved in transcriptional regulation, human immunodeficiency virus pathogenesis, DNA base excision repair, and…”
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Maltaricin CPN, a new class IIa bacteriocin produced by Carnobacterium maltaromaticumCPN isolated from mould-ripened cheese
Published in Journal of applied microbiology (01-11-2016)“…Aims The purpose of this study was to isolate, characterize and determine the structure and the antibacterial activities of a bacteriocin produced by…”
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Journal Article -
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Characterization of antibody drug conjugates by an innovative on-line four-dimensional HICxSEC-IM-MS methodology
Published in New biotechnology (10-10-2018)Get full text
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Homogeneous antibody-drug conjugates: DAR 2 anti-HER2 obtained by conjugation on isolated light chain followed by mAb assembly
Published in mAbs (01-01-2020)“…Despite advances in medical care, cancer remains a major threat to human health. Antibody-drug conjugates (ADCs) are a promising targeted therapy to overcome…”
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An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction
Published in Journal of molecular biology (06-11-2009)“…The tRNA-modifying enzyme tRNA-guanine transglycosylase (Tgt) is a putative target for new selective antibiotics against Shigella bacteria. The formation of a…”
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A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions
Published in Retrovirology (12-11-2012)“…Sexual acquisition of the human immunodeficiency virus (HIV) through mucosal transmission may be prevented by using topically applied agents that block HIV…”
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Use of virtual screening for discovering anti-retroviral compounds interacting with the HIV-1 nucleocapsid protein
Published in Virus research (2012)Get full text
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Characterization of the Methionine Sulfoxide Reductase Activities of PILB, a Probable Virulence Factor from Neisseria meningitidis
Published in The Journal of biological chemistry (05-04-2002)“…PILB has been described as being involved in the virulence of bacteria of Neisseria genus. The PILB protein is composed of three subdomains. In the present…”
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Functional and Structural Characterization of 2‑Amino-4-phenylthiazole Inhibitors of the HIV‑1 Nucleocapsid Protein with Antiviral Activity
Published in ACS chemical biology (19-09-2014)“…The nucleocapsid protein (NC) is a highly conserved protein in diverse HIV-1 subtypes that plays a central role in virus replication, mainly by interacting…”
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