Search Results - "CHURIN, Yuri"
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Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2
Published in Laboratory investigation (01-03-2020)“…The endocannabinoid (EC) system has been implicated in the pathogenesis of several metabolic diseases, including nonalcoholic fatty liver disease (NAFLD). With…”
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2
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice
Published in Laboratory investigation (01-11-2020)“…Clinical studies demonstrated that nonalcoholic steatohepatitis is associated with liver-related outcomes in chronic hepatitis B. Furthermore, primary biliary…”
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3
Comparative Analysis of the Interaction of Helicobacter pylori with Human Dendritic Cells, Macrophages, and Monocytes
Published in Infection and Immunity (01-08-2012)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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4
Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration
Published in Nature cell biology (01-08-2005)“…Ras proteins control the signalling pathways that are responsible for normal growth and malignant transformation. Raf protein kinases are direct Ras effector…”
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5
Genomic Methylation Inhibits Expression of Hepatitis B Virus Envelope Protein in Transgenic Mice: A Non-Infectious Mouse Model to Study Silencing of HBV Surface Antigen Genes
Published in PloS one (30-12-2015)“…The Hepatitis B virus genome persists in the nucleus of virus infected hepatocytes where it serves as template for viral mRNA synthesis. Epigenetic…”
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Helicobacter pylori induces miR-155 in T cells in a cAMP-Foxp3-dependent manner
Published in PloS one (02-03-2010)“…Amongst the most severe clinical outcomes of life-long infections with Helicobacter pylori is the development of peptic ulcers and gastric…”
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7
Hepatitis B virus large surface protein: function and fame
Published in Hepatobiliary surgery and nutrition (01-02-2015)“…Chronic infection with hepatitis B virus (HBV) is the leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. HBV life cycle begins with viral…”
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Helicobacter pylori CagA Protein Targets the c-Met Receptor and Enhances the Motogenic Response
Published in The Journal of cell biology (28-04-2003)“…Infection with the human microbial pathogen Helicobacter pylori is assumed to lead to invasive gastric cancer. We find that H. pylori activates the hepatocyte…”
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Pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background
Published in PloS one (04-03-2014)“…While the immune pathogenesis caused by hepatitis B virus (HBV) infection has been studied extensively, little is known about direct pathogenic effects of HBV…”
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10
Helicobacter pylori HP0518 affects flagellin glycosylation to alter bacterial motility
Published in Molecular microbiology (01-12-2010)“…Helicobacter pylori is a human gastric pathogen associated with gastric and duodenal ulcers as well as gastric cancer. Mounting evidence suggests this…”
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11
Correction: pathological impact of hepatitis B virus surface proteins on the liver is associated with the host genetic background
Published in PloS one (01-05-2015)Get full text
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Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements
Published in PLoS biology (01-08-2010)“…Certain bacterial adhesins appear to promote a pathogen's extracellular lifestyle rather than its entry into host cells. However, little is known about the…”
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IL-13 as Target to Reduce Cholestasis and Dysbiosis in Abcb4 Knockout Mice
Published in Cells (Basel, Switzerland) (24-08-2020)“…The Th2 cytokine IL-13 is involved in biliary epithelial injury and liver fibrosis in patients as well as in animal models. The aim of this study was to…”
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14
Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection
Published in PLoS pathogens (01-03-2009)“…Bcl-2 family proteins including the pro-apoptotic BH3-only proteins are central regulators of apoptotic cell death. Here we show by a focused siRNA miniscreen…”
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Schistosoma mansoni Egg–Secreted Antigens Activate Hepatocellular Carcinoma–Associated Transcription Factors c‐Jun and STAT3 in Hamster and Human Hepatocytes
Published in Hepatology (Baltimore, Md.) (01-08-2020)“…Clinical data have provided evidence that schistosomiasis can promote hepatocellular carcinogenesis. c‐Jun and STAT3 are critical regulators of liver cancer…”
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Helicobacter pylori type IV secretion, host cell signalling and vaccine development
Published in Keio journal of medicine (2002)“…Helicobacter pylori is a bacterial pathogen specialised to colonise and persist the gastric mucosa and to cause severe gastroduodenal disease. A major…”
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Helicobacter pylori outer membrane protein HopQ identified as a novel T4SS‐associated virulence factor
Published in Cellular microbiology (01-11-2013)“…Summary Helicobacter pylori is a bacterial pathogen that colonizes the gastric niche of ∼ 50% of the human population worldwide and is known to cause peptic…”
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Cholesterol glucosylation promotes immune evasion by Helicobacter pylori
Published in Nature medicine (01-09-2006)“…Helicobacter pylori infection causes gastric pathology such as ulcer and carcinoma. Because H. pylori is auxotrophic for cholesterol, we have explored the…”
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Modulation of the CD4⁺ T-Cell Response by Helicobacter pylori Depends on Known Virulence Factors and Bacterial Cholesterol and Cholesterol α-Glucoside Content
Published in The Journal of infectious diseases (01-11-2011)“…Helicobacter pylori blocks the proliferation of human CD4⁺ T cells, facilitated by vacuolating exotoxin (VacA) and γ-glutamyl transpeptidase (GGT). H…”
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Exogenous hepatitis B virus envelope proteins induce endoplasmic reticulum stress: involvement of cannabinoid axis in liver cancer cells
Published in Oncotarget (12-04-2016)“…HBV represents the most common chronic viral infection and major cause of hepatocellular carcinoma (HCC), although its exact role in liver tumorigenesis is…”
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