Search Results - "CHURCH, Nicole"

Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F, Warrington, John M, Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S, Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L, Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R, Dimitrov, Dimiter S, Stevanovic, Stefan, Sgourakis, Nikolaos G, Kiefel, Ben R, Maris, John M

“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
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Oxidation Behaviour of New Nickel-Base Superalloys with Varying Aluminium: Niobium Ratio by Wise, George J, Mignanelli Paul M, Hardy, Mark C, Church, Nicole L, Jones, Nicholas G, Stone, Howard J

“…New Ni-base superalloys with higher temperature capability are required for future, more efficient gas turbine engines. In designing such alloys, careful…”
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Notch ligand delta-like1: X-ray crystal structure and binding affinity by Kershaw, Nadia J, Church, Nicole L, Griffin, Michael D W, Luo, Cindy S, Adams, Timothy E, Burgess, Antony W

“…The Notch pathway is a fundamental signalling system in most multicellular animals. We have determined the X-ray crystal structure of the extracellular domain…”
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Targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…The majority of oncogenic drivers are intracellular proteins, constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by…”
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Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…Following the publication of our manuscript, a new high-resolution structure of the HLA-A·24:02/PHOX2B peptide/10LH scFv complex by X-ray crystallography…”
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Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion by Sun, Yi, Florio, Tyler J, Gupta, Sagar, Young, Michael C, Marshall, Quinlen F, Garfinkle, Samuel E, Papadaki, Georgia F, Truong, Hau V, Mycek, Emily, Li, Peiyao, Farrel, Alvin, Church, Nicole L, Jabar, Shereen, Beasley, Matthew D, Kiefel, Ben R, Yarmarkovich, Mark, Mallik, Leena, Maris, John M, Sgourakis, Nikolaos G

“…Peptide-centric chimeric antigen receptors (PC-CARs) recognize oncoprotein epitopes displayed by cell-surface human leukocyte antigens (HLAs) and offer a…”
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Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity by Layton, Meredith J, Saad, Mirette, Church, Nicole L, Pearson, Richard B, Mitchell, Christina A, Phillips, Wayne A

“…The α-isoform of the Type 1A Phosphoinositide 3-kinases (PI3Kα) has protein kinase activity as well as phosphoinositide lipid kinase activity. The best…”
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Immunopurification of adenomatous polyposis coli (APC) proteins by Elliott, Kerryn L, Catimel, Bruno, Church, Nicole L, Coates, Janine L, Burgess, Antony W, Layton, Meredith J, Faux, Maree C

“…The adenomatous polyposis coli (APC) tumour suppressor gene encodes a 2843 residue (310 kDa) protein. APC is a multifunctional protein involved in the…”
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Identification of a Wnt-induced protein complex by affinity proteomics using an antibody that recognizes a sub-population of β-catenin by Layton, Meredith J., Faux, Maree C., Church, Nicole L., Catimel, Bruno, Kershaw, Nadia J., Kapp, Eugene A., Nowell, Cameron, Coates, Janine L., Burgess, Antony W., Simpson, Richard J.

“…β-catenin is a signaling protein with diverse functions in cell adhesion and Wnt signaling. Although β-catenin has been shown to participate in many…”
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Solubilisation of the armadillo-repeat protein β-catenin using a zwitterionic detergent allows resolution of phosphorylated forms by 2DE by Layton, Meredith J., Church, Nicole L., Faux, Maree C., Ji, Hong, Goode, Robert J.A., Kapp, Eugene A., Burgess, Antony W., Simpson, Richard J.

“…β‐catenin is a member of the armadillo repeat family of proteins and has important functions in cell–cell adhesion and Wnt signalling. Different protein…”
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Do dysfunctional cognitions mediate the relationship between risk factors and postnatal depression symptomatology? by Church, Nicole F., Brechman-Toussaint, Margaret L., Hine, Donald W.

“…This study investigated the mediating role of general and maternal-specific dysfunctional cognitions, in the relationship between non-cognitive risk factors…”
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Development of a novel Ti-Nb-Au superelastic alloy with exceptionally low elastic modulus by Church, Nicole L., Prasad, Ayush, Talbot, Christian E.P., Reed, Oliver G., Jones, Nicholas G.

“…Infection is the leading cause of biomedical implant failure, making the incorporation of antibacterial elements highly desirable. However, new alloys must…”
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Understanding the Room Temperature Recovery Behavior in a Ti–24Nb–4Zr–8Sn Superelastic Alloy by Reed, Oliver G., Church, Nicole L., Jones, Nicholas G.

“…Metastable β Ti–Nb‐based superelastic alloys have potential uses in the biomedical and aerospace industries due to an attractive combination of properties…”
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Microstructural Stability and Properties of New Nickel‐Base Superalloys with Varying Aluminium: Niobium Ratio by Wise, George J., Miller, James R., Church, Nicole L., Mignanelli, Paul M., Hardy, Mark C., Jones, Nicholas G., Stone, Howard J.

“…New nickel‐base superalloys with higher temperature capability are required for future, more efficient gas turbine engines. In designing such alloys, careful…”
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RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs by Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.

“…The majority of oncogenic drivers are intracellular proteins, thus constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented…”
Get full text

The PI(3)P interactome from a colon cancer cell by Catimel, Bruno, Kapp, Eugene, Yin, Meng-Xin, Gregory, Mark, Wong, Leon S.-M., Condron, Melanie, Church, Nicole, Kershaw, Nadia, Holmes, Andrew B., Burgess, Antony W.

“…A comprehensive analysis of the phosphoinositide interactome has been performed using an ω-amino analogue of phosphatidylinositol 3-phosphate (PI(3)P…”
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Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide by Ngoei, Kevin R W, Catimel, Bruno, Church, Nicole, Lio, Daisy S, Dogovski, Con, Perugini, Matthew A, Watt, Paul M, Cheng, Heung-Chin, Ng, Dominic C H, Bogoyevitch, Marie A

“…An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein kinase…”
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In situ phosphorylation of immobilized receptors on biosensor surfaces: Application to E-cadherin/β-catenin interactions by Catimel, Bruno, Layton, Meredith, Church, Nicole, Ross, Janine, Condron, Melanie, Faux, Maree, Simpson, Richard J., Burgess, Antony W., Nice, Edouard C.

“…Phosphorylation is a key posttranslational modification for modulating biological interactions. Biosensor technology is ideally suited for examining in real…”
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Development of a novel Ti-Nb-Au superelastic alloy with exceptionally low elastic modulus by Church, Nicole L., Prasad, Ayush, Talbot, Christian E.P., Reed, Oliver G., Jones, Nicholas G.

“…Infection is the leading cause of biomedical implant failure, making the incorporation of antibacterial elements highly desirable. However, new alloys must…”
Get full text