Search Results - "CHURCH, D"

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity by Jeffery, Elise, Church, Christopher D., Holtrup, Brandon, Colman, Laura, Rodeheffer, Matthew S.

“…Excessive accumulation of white adipose tissue (WAT) is the defining characteristic of obesity. WAT mass is composed primarily of mature adipocytes, which are…”
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Human infections due to Staphylococcus pseudintermedius, an emerging zoonosis of canine origin: report of 24 cases by Somayaji, R., Priyantha, M.A.R., Rubin, J.E., Church, D.

“…Staphylococcus pseudintermedius has been recently identified as a novel species within the genus Staphylococcus, and is commonly associated with infections in…”
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The Adipose Tissue Microenvironment Regulates Depot-Specific Adipogenesis in Obesity by Jeffery, Elise, Wing, Allison, Holtrup, Brandon, Sebo, Zachary, Kaplan, Jennifer L., Saavedra-Peña, Rocio, Church, Christopher D., Colman, Laura, Berry, Ryan, Rodeheffer, Matthew S.

“…The sexually dimorphic distribution of adipose tissue influences the development of obesity-associated pathologies. The accumulation of visceral white adipose…”
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Insights into anti-tumor immunity via the polyomavirus shared across human Merkel cell carcinomas by Jani, Saumya, Church, Candice D, Nghiem, Paul

“…Understanding and augmenting cancer-specific immunity is impeded by the fact that most tumors are driven by patient-specific mutations that encode unique…”
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Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA by Paulson, K. G., Voillet, V., McAfee, M. S., Hunter, D. S., Wagener, F. D., Perdicchio, M., Valente, W. J., Koelle, S. J., Church, C. D., Vandeven, N., Thomas, H., Colunga, A. G., Iyer, J. G., Yee, C., Kulikauskas, R., Koelle, D. M., Pierce, R. H., Bielas, J. H., Greenberg, P. D., Bhatia, S., Gottardo, R., Nghiem, P., Chapuis, A. G.

“…Understanding mechanisms of late/acquired cancer immunotherapy resistance is critical to improve outcomes; cellular immunotherapy trials offer a means to probe…”
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Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children by Zinter, Matt S, Dvorak, Christopher C, Mayday, Madeline Y, Iwanaga, Kensho, Ly, Ngoc P, McGarry, Meghan E, Church, Gwynne D, Faricy, Lauren E, Rowan, Courtney M, Hume, Janet R, Steiner, Marie E, Crawford, Emily D, Langelier, Charles, Kalantar, Katrina, Chow, Eric D, Miller, Steve, Shimano, Kristen, Melton, Alexis, Yanik, Gregory A, Sapru, Anil, DeRisi, Joseph L

“…Abstract Background Despite improved diagnostics, pulmonary pathogens in immunocompromised children frequently evade detection, leading to significant…”
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Development and evaluation of a novel fast broad-range PCR and sequencing assay (FBR-PCR/S) using dual priming oligonucleotides targeting the ITS/LSU gene regions for rapid diagnosis of invasive fungal diseases: multi-year experience in a large Canadian healthcare zone by Chow, B, Groeschel, M, Carson, J, Griener, T, Church, D L

“…This study evaluated the performance of a novel fast broad range PCR and sequencing (FBR-PCR/S) assay for the improved diagnosis of invasive fungal disease…”
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Practical guidance for mismatch repair-deficiency testing in endometrial cancer by Stelloo, E., Jansen, A.M.L., Osse, E.M., Nout, R.A., Creutzberg, C.L., Ruano, D., Church, D.N., Morreau, H., Smit, V.T.H.B.M., van Wezel, T., Bosse, T.

“…Mismatch repair (MMR)-deficiency analysis is increasingly recommended for all endometrial cancers, as it identifies Lynch syndrome patients, and is emerging as…”
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Isolation and study of adipocyte precursors by Church, Christopher D, Berry, Ryan, Rodeheffer, Matthew S

“…White adipose tissue (WAT) is a heterogeneous tissue composed of lipid-filled adipocytes and several nonadipocyte cell populations, including endothelial,…”
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Colistin-Nonsusceptible Pseudomonas aeruginosa Sequence Type 654 with blaNDM-1 Arrives in North America by Mataseje, L F, Peirano, G, Church, D L, Conly, J, Mulvey, M, Pitout, J D

“…This study describes 3 different blaNDM-1 genetic platforms in 3 different species obtained from the same patient who was directly transferred to an…”
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Redefining geriatric preoperative assessment using frailty, disability and co-morbidity by Robinson, Thomas N, Eiseman, Ben, Wallace, Jeffrey I, Church, Skotti D, McFann, Kim K, Pfister, Shirley M, Sharp, Terra J, Moss, Marc

“…(1) Determine the relationship of geriatric assessment markers to 6-month postoperative mortality in elderly patients. (2) Create a clinical prediction rule…”
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Essential Amino Acids and Protein Synthesis: Insights into Maximizing the Muscle and Whole-Body Response to Feeding by Church, David D, Hirsch, Katie R, Park, Sanghee, Kim, Il-Young, Gwin, Jess A, Pasiakos, Stefan M, Wolfe, Robert R, Ferrando, Arny A

“…Ingesting protein-containing supplements and foods provides essential amino acids (EAA) necessary to increase muscle and whole-body protein synthesis (WBPS)…”
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Multi-year comparison of VITEK® MS and 16S rRNA gene sequencing performance for the identification of rarely encountered anaerobes causing invasive human infections in a large Canadian region: can our laboratory abandon 16S rRNA gene sequencing? by Church, D.L., Griener, T., Gregson, D.

“…Our large regional laboratory routinely provides a definitive identification (ID) for 800-1,200 anaerobic bacteria per annum that cause invasive human…”
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Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices by Buckland, E. L., O'Neill, D., Summers, J., Mateus, A., Church, D., Redmond, L., Brodbelt, D.

“…There is scant evidence describing antimicrobial (AM) usage in companion animal primary care veterinary practices in the UK. The use of AMs in dogs and cats…”
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Adult onset global loss of the fto gene alters body composition and metabolism in the mouse by McMurray, Fiona, Church, Chris D, Larder, Rachel, Nicholson, George, Wells, Sara, Teboul, Lydia, Tung, Y C Loraine, Rimmington, Debra, Bosch, Fatima, Jimenez, Veronica, Yeo, Giles S H, O'Rahilly, Stephen, Ashcroft, Frances M, Coll, Anthony P, Cox, Roger D

“…The strongest BMI-associated GWAS locus in humans is the FTO gene. Rodent studies demonstrate a role for FTO in energy homeostasis and body composition. The…”
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Muscle Protein Synthesis and Whole-Body Protein Turnover Responses to Ingesting Essential Amino Acids, Intact Protein, and Protein-Containing Mixed Meals with Considerations for Energy Deficit by Gwin, Jess A, Church, David D, Wolfe, Robert R, Ferrando, Arny A, Pasiakos, Stefan M

“…Protein intake recommendations to optimally stimulate muscle protein synthesis (MPS) are derived from dose-response studies examining the stimulatory effects…”
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Prevalence of disorders recorded in cats attending primary-care veterinary practices in England by O'Neill, D.G., Church, D.B., McGreevy, P.D., Thomson, P.C., Brodbelt, D.C.

“…•This study demonstrated that the most prevalent disorders of cats presented to primary-care veterinary practices in Central and South-East England were…”
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Longevity and mortality of owned dogs in England by O’Neill, D.G., Church, D.B., McGreevy, P.D., Thomson, P.C., Brodbelt, D.C.

“…Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity…”
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Unravelling the health status of brachycephalic dogs in the UK using multivariable analysis by O’Neill, D. G., Pegram, C., Crocker, P., Brodbelt, D. C., Church, D. B., Packer, R. M. A.

“…Brachycephalic dog breeds are regularly asserted as being less healthy than non-brachycephalic breeds. Using primary-care veterinary clinical data, this study…”
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Molecular epidemiology of Escherichia coli causing bloodstream infections in a centralized Canadian region: a population-based surveillance study by Holland, M.S., Nobrega, D., Peirano, G., Naugler, C., Church, D.L., Pitout, J.D.D.

“…Escherichia coli is a leading cause of bloodstream infections worldwide, and is responsible for substantial patient morbidity, mortality and healthcare…”
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