Search Results - "CHUQUIYAURI, Raul"
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Temporal and Microspatial Heterogeneity in Transmission Dynamics of Coendemic Plasmodium vivax and Plasmodium falciparum in Two Rural Cohort Populations in the Peruvian Amazon
Published in The Journal of infectious diseases (23-04-2021)“…Abstract Background Malaria is highly heterogeneous: its changing malaria microepidemiology needs to be addressed to support malaria elimination efforts at the…”
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Micro-heterogeneity of malaria transmission in the Peruvian Amazon: a baseline assessment underlying a population-based cohort study
Published in Malaria journal (04-08-2017)“…Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control…”
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3
Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea
Published in Malaria journal (24-03-2022)“…Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to…”
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4
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria
Published in The New England journal of medicine (17-01-2019)Get full text
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5
Incidence of Plasmodium falciparum malaria infection in 6-month to 45-year-olds on selected areas of Bioko Island, Equatorial Guinea
Published in Malaria journal (20-07-2021)“…Abstract Background Extensive malaria control measures have been implemented on Bioko Island, Equatorial Guinea over the past 16 years, reducing parasite…”
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Genome-Scale Protein Microarray Comparison of Human Antibody Responses in Plasmodium vivax Relapse and Reinfection
Published in The American journal of tropical medicine and hygiene (01-10-2015)“…Large scale antibody responses in Plasmodium vivax malaria remains unexplored in the endemic setting. Protein microarray analysis of asexual-stage P. vivax was…”
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7
Whole genome sequencing analysis of Plasmodium vivax using whole genome capture
Published in BMC genomics (21-06-2012)“…Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations,…”
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Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study
Published in The Lancet infectious diseases (01-08-2018)“…DSM265 is a novel, long-duration inhibitor of plasmodium dihydroorotate dehydrogenase (DHODH) with excellent selectivity over human DHODH and activity against…”
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Single-Dose Tafenoquine to Prevent Relapse of Plasmodium vivax Malaria
Published in The New England journal of medicine (17-01-2019)“…Clearing of the dormant liver stage (the hypnozoite) of P. vivax malaria is important to prevent the relapse of infection. In this randomized clinical trial, a…”
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10
Tafenoquine versus Primaquine to Prevent Relapse of Plasmodium vivax Malaria
Published in The New England journal of medicine (17-01-2019)“…Malaria remains a global health burden. Elimination of the hypnozoite is required in patients infected with P. vivax to prevent relapse. In this report, the…”
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Multi-Dose Priming Regimens of PfSPZ Vaccine: Safety and Efficacy against Controlled Human Malaria Infection in Equatoguinean Adults
Published in The American journal of tropical medicine and hygiene (06-04-2022)“…Plasmodium falciparum sporozoite (PfSPZ) Vaccine is composed of radiation-attenuated, aseptic, purified cryopreserved PfSPZ. Multiple clinical trials…”
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12
Infection of laboratory-colonized Anopheles darlingi mosquitoes by Plasmodium vivax
Published in The American journal of tropical medicine and hygiene (01-04-2014)“…Anopheles darlingi Root is the most important malaria vector in the Amazonia region of South America. However, continuous propagation of An. darlingi in the…”
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Human host-derived cytokines associated with Plasmodium vivax transmission from acute malaria patients to Anopheles darlingi mosquitoes in the Peruvian Amazon
Published in The American journal of tropical medicine and hygiene (01-06-2013)“…Infection of mosquitoes by humans is not always successful in the setting of patent gametocytemia. This study tested the hypothesis that pro- or…”
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Socio-demographics and the development of malaria elimination strategies in the low transmission setting
Published in Acta tropica (01-03-2012)“…This analysis presents a comprehensive description of malaria burden and risk factors in the Peruvian Amazon. Socio-demographic studies are key to direct…”
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15
Accelerating to Zero: Strategies to Eliminate Malaria in the Peruvian Amazon
Published in The American journal of tropical medicine and hygiene (01-06-2016)“…AbstractIn February 2014, the Malaria Elimination Working Group, in partnership with the Peruvian Ministry of Health (MoH), hosted its first international…”
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Microgeographical differences of Plasmodium vivax relapse and re-infection in the Peruvian Amazon
Published in The American journal of tropical medicine and hygiene (01-08-2013)“…To determine the magnitude of Plasmodium vivax relapsing malaria in rural Amazonia, we carried out a study in four sites in northeastern Peru. Polymerase chain…”
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Malaria in the Peruvian Amazon
Published 01-01-2014“…Malaria is the most widespread serious parasitic disease worldwide, with over 2 billion people at risk of infection, over 300 million cases yearly, and over 1…”
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Dissertation -
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Malaria in the Peruvian Amazon
Published 01-01-2014“…Malaria is the most widespread serious parasitic disease worldwide, with over 2 billion people at risk of infection, over 300 million cases yearly, and over 1…”
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Dissertation -
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Experimental infection of the neotropical malaria vector Anopheles darlingi by human patient-derived Plasmodium vivax in the Peruvian Amazon
Published in The American journal of tropical medicine and hygiene (01-10-2006)“…Malaria transmission from humans to mosquitoes is modulated by human host immune factors. Understanding mechanisms by which the human host response may impair…”
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Journal Article -
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High Degree of Plasmodium vivax Diversity in the Peruvian Amazon Demonstrated by Tandem Repeat Polymorphism Analysis
Published in The American journal of tropical medicine and hygiene (01-04-2012)“…Molecular tools to distinguish strains of Plasmodium vivax are important for studying the epidemiology of malaria transmission. Two sets of markers-tandem…”
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