Search Results - "CHUNG, Cecilia P"

Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death by Ray, Wayne A, Chung, Cecilia P, Murray, Katherine T, Hall, Kathi, Stein, C. Michael

“…It is known that the use of typical antipsychotic agents (e.g., haloperidol) is associated with an increased risk of sudden cardiac death. This study shows…”
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An automated database case definition for serious bleeding related to oral anticoagulant use by Cunningham, Andrew, Stein, C. Michael, Chung, Cecilia P., Daugherty, James R., Smalley, Walter E., Ray, Wayne A.

“…ABSTRACT Purpose Bleeding complications are a serious adverse effect of medications that prevent abnormal blood clotting. To facilitate epidemiologic…”
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Heart Failure Risk Associated With Rheumatoid Arthritis-Related Chronic Inflammation by Ahlers, Michael J, Lowery, Brandon D, Farber-Eger, Eric, Wang, Thomas J, Bradham, William, Ormseth, Michelle J, Chung, Cecilia P, Stein, C Michael, Gupta, Deepak K

“…Background Inflammation may contribute to incident heart failure (HF). Rheumatoid arthritis (RA), a prototypic inflammatory condition, may serve as a model for…”
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Mortality and concurrent use of opioids and hypnotics in older patients: A retrospective cohort study by Ray, Wayne A, Chung, Cecilia P, Murray, Katherine T, Malow, Beth A, Daugherty, James R, Stein, C. Michael

“…Background Benzodiazepine hypnotics and the related nonbenzodiazepine hypnotics (z-drugs) are among the most frequently prescribed medications for older…”
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Genome-wide association analyses of common infections in a large practice-based biobank by Jiang, Lan, Kerchberger, V Eric, Shaffer, Christian, Dickson, Alyson L, Ormseth, Michelle J, Daniel, Laura L, Leon, Barbara G Carranza, Cox, Nancy J, Chung, Cecilia P, Wei, Wei-Qi, Stein, C Michael, Feng, QiPing

“…Infectious diseases are common causes of morbidity and mortality worldwide. Susceptibility to infection is highly heritable; however, little has been done to…”
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Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records by Feng, QiPing, Wei, Wei-Qi, Chung, Cecilia P, Levinson, Rebecca T, Sundermann, Alexandra C, Mosley, Jonathan D, Bastarache, Lisa, Ferguson, Jane F, Cox, Nancy J, Roden, Dan M, Denny, Joshua C, Linton, MacRae F, Edwards, Digna R Velez, Stein, C Michael

“…Observations from statin clinical trials and from Mendelian randomization studies suggest that low low-density lipoprotein cholesterol (LDL-C) concentrations…”
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High-throughput framework for genetic analyses of adverse drug reactions using electronic health records by Zheng, Neil S, Stone, Cosby A, Jiang, Lan, Shaffer, Christian M, Kerchberger, V Eric, Chung, Cecilia P, Feng, QiPing, Cox, Nancy J, Stein, C Michael, Roden, Dan M, Denny, Joshua C, Phillips, Elizabeth J, Wei, Wei-Qi

“…Understanding the contribution of genetic variation to drug response can improve the delivery of precision medicine. However, genome-wide association studies…”
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Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study by Jiang, Lan, Liu, Ge, Oeser, Annette, Ihegword, Andrea, Dickson, Alyson L, Daniel, Laura L, Hung, Adriana M, Cox, Nancy J, Chung, Cecilia P, Wei, Wei-Qi, Stein, C Michael, Feng, Qiping

“…Two risk variants in the apolipoprotein L1 gene ( ) have been associated with increased susceptibility to sepsis in Black patients. However, it remains unclear…”
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Prevalence of Traditional Modifiable Cardiovascular Risk Factors in Patients with Rheumatoid Arthritis: Comparison with Control Subjects from the Multi-Ethnic Study of Atherosclerosis by Chung, Cecilia P., MD, MPH, Giles, Jon T., MD, MPH, Petri, Michelle, MD, MPH, Szklo, Moyses, MD, DrPH, Post, Wendy, MD, MS, Blumenthal, Roger S., MD, Gelber, Allan C., MD, MPH, PhD, Ouyang, Pamela, MD, Jenny, Nancy S., PhD, Bathon, Joan M., MD

“…Objective Despite the recognized risk of accelerated atherosclerosis in patients with rheumatoid arthritis (RA), little is known about cardiovascular risk…”
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Novel Cardiovascular Risk Factors in Premature Coronary Atherosclerosis Associated with Systemic Lupus Erythematosus by YOUNG HEE RHO, CHUNG, Cecilia P, OESER, Annette, SOLUS, Joseph, RAGGI, Paolo, GEBRETSADIK, Tebeb, SHINTANI, Ayumi, STEIN, C. Michael

“…Objective Several mediators of inflammation are associated with atherosclerotic cardiovascular disease in the general population, but their relationship to…”
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Intermuscular adipose tissue in patients with systemic lupus erythematosus by Gamboa, Jorge Luis, Carranza-León, Daniel, Crescenzi, Rachelle, Pridmore, Michael, Peng, Dungeng, Marton, Adriana, Oeser, Annette, Chung, Cecilia P, Titze, Jens, Stein, Charles Michael, Ormseth, Michelle

“…ObjectivePatients with SLE frequently have debilitating fatigue and reduced physical activity. Intermuscular adipose tissue (IMAT) accumulation is associated…”
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From Genes to Endogenous Substrates: Towards a Better Understanding of Drug Metabolizing Enzymes by Chung, Cecilia P.

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The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach by Liu, Ge, Jiang, Lan, Kerchberger, V. Eric, Oeser, Annette, Ihegword, Andrea, Dickson, Alyson L., Daniel, Laura L., Shaffer, Christian, Linton, MacRae F., Cox, Nancy, Chung, Cecilia P., Wei, Wei‐Qi, Stein, C. Michael, Feng, QiPing

“…Sepsis accounts for one in three hospital deaths. Higher concentrations of high‐density lipoprotein cholesterol (HDL‐C) are associated with apparent protection…”
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Pharmacogenetic variants and risk of remdesivir‐associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID‐19 by Tuteja, Sony, Yu, Zhihong, Wilson, Otis, Chen, Hua‐Chang, Wendt, Frank, Chung, Cecilia P., Shah, Shailja C., Hunt, Christine M., Suzuki, Ayako, Chanfreau, Catherine, Gorman, Bryan R., Joseph, Jacob, Luoh, Shiuh‐Wen, Napolioni, Valerio, Robinson‐Cohen, Cassianne, Tao, Ran, Zhou, Jin, Chang, Kyong‐Mi, Hung, Adriana M.

“…Remdesivir is the first US Food and Drug Administration (FDA)‐approved drug for the treatment of coronavirus disease 2019 (COVID‐19). We conducted a…”
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Clinical diagnoses associated with a positive antinuclear antibody test in patients with and without autoimmune disease by Zanussi, Jacy T, Zhao, Juan, Wei, Wei-Qi, Karakoc, Gul, Chung, Cecilia P, Feng, QiPing, Olsen, Nancy J, Stein, C Michael, Kawai, Vivian K

“…Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a…”
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Ancestry, ACKR1 and leucopenia in patients with systemic lupus erythematosus by Chung, Cecilia P, Karakoc, Gul, Liu, Ge, Gamboa, Jorge L, Mosley, Jonathan D, Cox, Nancy J, Stein, C Michael, Kawai, Vivian

“…ObjectiveSLE is more prevalent in populations of African (AA) than European ancestry (EA) and leucopenia is common. A homozygous variant in ACKR1…”
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Inflammatory mediators and premature coronary atherosclerosis in rheumatoid arthritis by Rho, Young Hee, Chung, Cecilia P., Oeser, Annette, Solus, Joseph, Asanuma, Yu, Sokka, Tuulikki, Pincus, Theodore, Raggi, Paolo, Gebretsadik, Tebeb, Shintani, Ayumi, Stein, C. Michael

“…Objective Rheumatoid arthritis (RA) is an inflammatory disease associated with premature atherosclerosis. We hypothesized that mediators of inflammation…”
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Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity by Daniel, Laura L., Dickson, Alyson L., Zanussi, Jacy T., Miller‐Fleming, Tyne W., Straub, Peter S., Wei, Wei‐Qi, Plummer, W. Dale, Dupont, William D., Liu, Ge, Anandi, Prathima, Reese, Tyler S., Birdwell, Kelly A., Kawai, Vivian K., Hung, Adriana M., Cox, Nancy J., Feng, QiPing, Stein, C. Michael, Chung, Cecilia P.

“…TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could…”
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Increased concentration of proatherogenic inflammatory cytokines in systemic lupus erythematosus: relationship to cardiovascular risk factors by ASANUMA, Yu, CHUNG, Cecilia P, OESER, Annette, SHINTANI, Ayumi, STANLEY, Eran, RAGGI, Paolo, STEIN, C. Michael

“…OBJECTIVE:. To examine the hypothesis that patients with systemic lupus erythematosus (SLE) have increased concentrations of interleukin-6 (IL-6), IL-8, and…”
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Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease by Ray, Wayne A, Varas-Lorenzo, Cristina, Chung, Cecilia P, Castellsague, Jordi, Murray, Katherine T, Stein, C Michael, Daugherty, James R, Arbogast, Patrick G, García-Rodríguez, Luis A

“…The cardiovascular safety of individual nonsteroidal antiinflammatory drugs (NSAIDs) is highly controversial, particularly in persons with serious coronary…”
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