Search Results - "CHUNFA JIE"
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HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
Published in Cancer research (Chicago, Ill.) (15-04-2018)“…Systemic inflammation in breast cancer correlates with poor prognosis, but the molecular underpinnings of this connection are not well understood. In this…”
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2
Expression of unique gene signature distinguishes TCRαβ+/BCR+ dual expressers from CD3+CD14+ doublets
Published in Cytometry. Part A (01-04-2022)“…Increasing evidence shows pathophysiological significance of rare immune cells, necessitating the need for reliable and proper methods for their detection and…”
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3
Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice
Published in Glia (01-02-2011)“…Astrocyte heterogeneity remains largely unknown in the CNS due to lack of specific astroglial markers. In this study, molecular identity of in vivo astrocytes…”
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4
Potentially inappropriate medication prescribing in the elderly: Is the Beers Criteria relevant in the Emergency Department today?
Published in The American journal of emergency medicine (01-09-2019)“…To investigate the frequency of Beers Criteria (BC) medication and opioid use in patients age 65 years and older arriving in the Emergency Department. We…”
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5
Molecular causes of the aberrant choline phospholipid metabolism in breast cancer
Published in Cancer research (Chicago, Ill.) (15-06-2004)“…Proton magnetic resonance spectroscopy ((1)H MRS) consistently detects significant differences in choline phospholipid metabolites of malignant versus benign…”
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6
Chronic CD4+ T-Cell Activation and Depletion in Human Immunodeficiency Virus Type 1 Infection: Type I Interferon-Mediated Disruption of T-Cell Dynamics
Published in Journal of Virology (01-02-2008)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Two Clinical Phenotypes in Polycythemia Vera
Published in The New England journal of medicine (28-08-2014)“…Analysis of gene expression in CD34+ cells from patients with polycythemia vera indicated two main genotypes that correlated with a variety of clinical…”
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8
Gene expression profiling reveals early cellular responses to intracellular magnetic labeling with superparamagnetic iron oxide nanoparticles
Published in Magnetic resonance in medicine (01-04-2010)“…With MRI (stem) cell tracking having entered the clinic, studies on the cellular genomic response toward labeling are warranted. Gene expression profiling was…”
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9
Proteomic profiling of cancer stem cells derived from primary tumors of HER2/Neu transgenic mice
Published in Proteomics (Weinheim) (01-11-2012)“…Human epidermal growth factor receptor 2 (HER2) overexpression leads to mammary tumorigenesis and its elevated levels lead to increase in cancer stem cells…”
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10
Reducing stigma and increasing competence working with mental illness: Adaptation of a contact-based program for osteopathic medical students to a virtual, active learning format
Published in Medical education online (01-12-2023)“…Contact-based education, offering meaningful contact with individuals living in recovery with mental illness, reduces stigma. This study evaluated the…”
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11
GEAMP, a novel gastroesophageal junction carcinoma cell line derived from a malignant pleural effusion
Published in Laboratory investigation (01-01-2020)“…Gastroesophageal junction (GEJ) cancer remains a clinically significant disease in Western countries due to its increasing incidence, which mirrors that of…”
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12
Analysis of mesenchymal stem cell proteomes in situ in the ischemic heart
Published in Theranostics (01-01-2020)“…Rationale: Cell therapy for myocardial infarction is promising but largely unsuccessful in part due to a lack of mechanistic understanding. Techniques enabling…”
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13
Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes
Published in The Journal of clinical investigation (01-03-2008)“…Although the differentiation of ES cells to cardiomyocytes has been firmly established, the extent to which corresponding cardiac precursor cells can…”
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14
Central role of ULK1 in type I interferon signaling
Published in Cell reports (Cambridge) (28-04-2015)“…We provide evidence that the Unc-51-like kinase 1 (ULK1) is activated during engagement of the type I interferon (IFN) receptor (IFNR). Our studies demonstrate…”
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15
A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma
Published in International journal of cancer (15-03-2011)“…Nasopharyngeal carcinoma (NPC) is a rare malignancy with unique genetic, viral and environmental characteristic that distinguishes it from other head and neck…”
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16
Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas
Published in Neoplasia (New York, N.Y.) (01-06-2019)“…BACKGROUND: Ependymomas (EPNs) are the third most common brain tumor in children. These tumors are resistant to available chemotherapeutic treatments,…”
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The effect of vorinostat on the development of resistance to doxorubicin in neuroblastoma
Published in PloS one (19-07-2012)“…Histone deacetylase (HDAC) inhibitors, especially vorinostat, are currently under investigation as potential adjuncts in the treatment of neuroblastoma. The…”
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Anticancer activity and mechanism of Scutellaria barbata extract on human lung cancer cell line A549
Published in Life sciences (1973) (17-09-2004)“…Scutellaria barbata ( S. barbata) , a traditional Chinese herbal medicine native to southern China, is widely used as an anti-inflammatory and a diuretic in…”
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Role of NADPH Oxidase in Arsenic-Induced Reactive Oxygen Species Formation and Cytotoxicity in Myeloid Leukemia Cells
Published in Proceedings of the National Academy of Sciences - PNAS (30-03-2004)“…Arsenic has played a key medicinal role against a variety of ailments for several millennia, but during the past century its prominence has been displaced by…”
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20
Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2010)“…Ectopic Myc expression plays a key role in human tumorigenesis, and Myc dose-dependent tumorigenesis has been well established in transgenic mice, but the Myc…”
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