Search Results - "CHUANG, ALICE Y"

Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure by Huang, Yiping, Chuang, Alice Y., Ratovitski, Edward A.

“…The cisplatin-induced ATM-dependent phosphorylated (p)-ΔNp63α plays an important role in transcriptional regulation of specific genes encoding mRNAs and…”
Get full text

A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: Creation and rationale for inclusion of tumor (T) characteristics by Farasat, Sharifeh, BS, Yu, Siegrid S., MD, Neel, Victor A., MD, PhD, Nehal, Kishwer S., MD, Lardaro, Thomas, BSc, Mihm, Martin C., MD, Byrd, David R., MD, Balch, Charles M., MD, Califano, Joseph A., MD, Chuang, Alice Y., MD, Sharfman, William H., MD, Shah, Jatin P., MD, PhD, Nghiem, Paul, MD, PhD, Otley, Clark C., MD, Tufaro, Anthony P., DDS, MD, Johnson, Timothy M., MD, Sober, Arthur J., MD, Liégeois, Nanette J., MD, PhD

“…Background The incidence of cutaneous squamous cell carcinoma (cSCC) is increasing. Although most patients achieve complete remission with surgical treatment,…”
Get full text

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma by Loyo, Myriam, Brait, Mariana, Kim, Myoung S., Ostrow, Kimberly L., Jie, Chunfa C., Chuang, Alice Y., Califano, Joseph A., Liégeois, Nanette J., Begum, Shahnaz, Westra, William H., Hoque, Mohammad O., Tao, Qian, Sidransky, David

“…Nasopharyngeal carcinoma (NPC) is a rare malignancy with unique genetic, viral and environmental characteristic that distinguishes it from other head and neck…”
Get full text

c-Myc Induces Chromosomal Rearrangements through Telomere and Chromosome Remodeling in the Interphase Nucleus by Louis, Sherif F., Vermolen, Bart J., Garini, Yuval, Young, Ian T., Guffei, Amanda, Lichtensztejn, Zelda, Kuttler, Fabien, Tony C. Y. Chuang, Moshir, Sharareh, Mougey, Virginie, Alice Y. C. Chuang, Kerr, Paul Donald, Fest, Thierry, Boukamp, Petra, Mai, Sabine, Klein, George

“…In previous work, we showed that telomeres of normal cells are organized within the 3D space of the interphase nucleus in a nonoverlapping and cell…”
Get full text

Differential expression of degradome components in cutaneous squamous cell carcinomas by Prasad, Nijaguna B, Fischer, Anne C, Chuang, Alice Y, Wright, Jerry M, Yang, Ting, Tsai, Hua-Ling, Westra, William H, Liegeois, Nanette J, Hess, Allan D, Tufaro, Anthony P

“…Although the cure rate for cutaneous squamous cell carcinoma is high, the diverse spectrum of squamous cell carcinoma has made it difficult for early…”
Get full text

Detectable BRAF mutation in serum DNA samples from patients with papillary thyroid carcinomas by Chuang, Tony C. Y., Chuang, Alice Y. C., Poeta, Luana, Koch, Wayne M., Califano, Joseph A., Tufano, Ralph P.

“…Background. An activating point mutation of the BRAF oncogene results in a V600E amino acid missense mutation found in a majority of papillary thyroid…”
Get full text

Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors by Durr, Megan L, Mydlarz, Wojciech K, Shao, Chunbo, Zahurak, Marianna L, Chuang, Alice Y, Hoque, Mohammad O, Westra, William H, Liegeois, Nanette J, Califano, Joseph A, Sidransky, David, Ha, Patrick K

“…Methylation profiling of tumor suppressor gene (TSGs) promoters is quickly becoming a powerful diagnostic tool for the early detection, prognosis, and even…”
Get full text

NOD2 expression is regulated by microRNAs in colonic epithelial HCT116 cells by Chuang, Alice Y, Chuang, Jim C, Zhai, Zili, Wu, Feng, Kwon, John H

“…Crohn's disease (CD) is associated with defective sensing of pathogens in genetically susceptible individuals. Nucleotide-binding oligomerization domain…”
Get full text

miR-106b fine tunes ATG16L1 expression and autophagic activity in intestinal epithelial HCT116 cells by Zhai, Zili, Wu, Feng, Chuang, Alice Y, Kwon, John H

“…The microRNAs (miRNAs) regulate gene expression at the posttranscriptional level. ATG16L1, an essential component for autophagy and a risk gene for Crohn's…”
Get full text

Human autophagy gene ATG16L1 is post-transcriptionally regulated by MIR142-3p by Zhai, Zili, Wu, Feng, Dong, Fengshi, Chuang, Alice Y, Messer, Jeannette S, Boone, David L, Kwon, John H

“…Multiple genetic studies have implicated the autophagy-related gene, ATG16L1, in the pathogenesis of Crohn disease (CD). While CD-related research on ATG16L1…”
Get full text

Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer by DEMOKAN, SEMRA, CHUANG, ALICE Y, PATTANI, KAVITA M, SIDRANSKY, DAVID, KOCH, WAYNE, CALIFANO, JOSEPH A

“…Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In the present…”
Get full text

Presence of HPV DNA in convalescent salivary rinses is an adverse prognostic marker in head and neck squamous cell carcinoma by Chuang, Alice Y, Chuang, Tony C, Chang, Steven, Zhou, Shaoyu, Begum, Shahnaz, Westra, William H, Ha, Patrick K, Koch, Wayne M, Califano, Joseph A

“…Summary Human papillomavirus (HPV) 16 is present in up to 60% of patients with head and neck squamous cell carcinoma (HNSCC) and confers a favorable prognosis…”
Get full text

Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling by DEMOKAN, SEMRA, CHUANG, ALICE Y, CHANG, XIAOFEI, KHAN, TANBIR, SMITH, IAN M, PATTANI, KAVITA M, DASGUPTA, SANTANU, BEGUM, SHAHNAZ, KHAN, ZUBAIR, LIEGEOIS, NANETTE J, WESTRA, WILLIAM H, SIDRANSKY, DAVID, KOCH, WAYNE, CALIFANO, JOSEPH A

“…Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. Aberrant hypermethylation in the promoter region of some known or…”
Get full text

Phospho-ΔNp63α/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure by Huang, Yiping, Chuang, Alice Y., Romano, Rose A., Liégeois, Nanette J., Sinha, Satrajit, Trink, Barry, Ratovitski, Edward A., Sidransky, David

“…Cisplatin remains the most important chemotherapeutic agent for patients with human head and neck cancer. However, tumor cells often develop resistance to…”
Get full text

Abstract 666: Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer by Demokan, Semra, Chuang, Alice Y., Pattani, Kavita M., Sidransky, David, Koch, Wayne, Califano, Joseph A.

“…Purpose: Methylation of CpG islands in the promoter region of genes acts as a significant mechanism of epigenetic gene silencing in head and neck cancer. In…”
Get full text

Abstract 1384: Promoter methylation of tumor suppressor genes in convalescent saliva samples from patients with head and neck squamous cell carcinoma by Demokan, Semra, Kaur, Jatinder, Chuang, Alice Y., Mydlarz, Wojciech K., Pattani, Kavita M., Koch, Wayne M., Sidransky, David, Dalay, Nejat, Califano, Joseph A.

“…Purpose: Silencing of tumor suppressor genes (TSGs) plays an important role in head and neck carcinogenesis. Methylation of CpG islands in the promoter regions…”
Get full text

Abstract 4041: Identification of GNG7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling by Demokan, Semra, Chuang, Alice Y., Chang, Xiaofei, Khan, Tanbir, Smith, Ian M., Pattani, Kavita M., Dasgupta, Santanu, Begum, Shahnaz, Khan, Zubair, Liegeois, Nanette J., Westra, William H., Sidransky, David, Koch, Wayne, Califano, Joseph A.

“…Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. Aberrant hypermethylation in the promoter region of some known or…”
Get full text

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure by Huang, Yiping, Chuang, Alice Y, Romano, Rose-Anne, Liégeois, Nanette J, Sinha, Satrajit, Trink, Barry, Ratovitski, Edward, Sidransky, David

“…Cisplatin remains the most important chemotherapeutic agent for patients with human head and neck cancer. However, tumor cells often develop resistance to…”
Get full text