Search Results - "CHUANFU LI"

Lactate Suppresses Macrophage Pro-Inflammatory Response to LPS Stimulation by Inhibition of YAP and NF-κB Activation via GPR81-Mediated Signaling by Yang, Kun, Xu, Jingjing, Fan, Min, Tu, Fei, Wang, Xiaohui, Ha, Tuanzhu, Williams, David L, Li, Chuanfu

“…Recent evidence from cancer research indicates that lactate exerts a suppressive effect on innate immune responses in cancer. This study investigated the…”
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Attenuation of Cardiac Dysfunction in Polymicrobial Sepsis by MicroRNA-146a Is Mediated via Targeting of IRAK1 and TRAF6 Expression by Gao, Ming, Wang, Xiaohui, Zhang, Xia, Ha, Tuanzhu, Ma, He, Liu, Li, Kalbfleisch, John H, Gao, Xiang, Kao, Race L, Williams, David L, Li, Chuanfu

“…Cardiac dysfunction is a major consequence of sepsis/septic shock and contributes to the high mortality of sepsis. Innate and inflammatory responses mediated…”
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Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis by Zheng, Zhibo, Ma, He, Zhang, Xia, Tu, Fei, Wang, Xiaohui, Ha, Tuanzhu, Fan, Min, Liu, Li, Xu, Jingjing, Yu, Kaijiang, Wang, Ruitao, Kalbfleisch, John, Kao, Race, Williams, David, Li, Chuanfu

“…Background. Cardiac dysfunction is present in >40% of sepsis patients and is associated with mortality rates of up to 70%. Recent evidence suggests that…”
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Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction by Fan, Min, Yang, Kun, Wang, Xiaohui, Chen, Linjian, Gill, P Spencer, Ha, Tuanzhu, Liu, Li, Lewis, Nicole H, Williams, David L, Li, Chuanfu

“…High levels of lactate are positively associated with the prognosis and mortality in patients with heart attack. Endothelial-to-mesenchymal transition (EndoMT)…”
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HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization by Kong, Qiuyue, Li, Nan, Cheng, Hao, Zhang, Xiaojin, Cao, Xiaofei, Qi, Tao, Dai, Leyang, Zhang, Zhihong, Chen, Xuan, Li, Chuanfu, Li, Yuehua, Xue, Bin, Fang, Lei, Liu, Li, Ding, Zhengnian

“…Nonalcoholic steatohepatitis (NASH) is the most prevalent cause of chronic liver disease worldwide. Macrophage-mediated inflammation plays a critical role in…”
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Scavenger receptor-A (CD204): a two-edged sword in health and disease by Kelley, Jim L, Ozment, Tammy R, Li, Chuanfu, Schweitzer, John B, Williams, David L

“…Scavenger receptor A (SR-A), also known as the macrophage scavenger receptor and cluster of differentiation 204 (CD204), plays roles in lipid metabolism,…”
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Sedimentation Behavior of Liquid Iron Droplets during Smelting Reduction of Converter Slag by Considering the Coalescence of Droplets by He, Meile, Chen, Min, Wang, Nan, Li, Chuanfu

“…To improve the sedimentation efficiency during the smelting reduction process of converter slag for iron extraction, the interaction and sedimentation behavior…”
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An Efficient CNN for Hand X-Ray Overall Scoring of Rheumatoid Arthritis by Wang, Zijian, Liu, Jian, Gu, Zongyun, Li, Chuanfu

“…Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease characterized by inflammation of the joints and surrounding tissues, which seriously…”
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MicroRNA-214 protects against hypoxia/reoxygenation induced cell damage and myocardial ischemia/reperfusion injury via suppression of PTEN and Bim1 expression by Wang, Xiaohui, Ha, Tuanzhu, Hu, Yuanping, Lu, Chen, Liu, Li, Zhang, Xia, Kao, Race, Kalbfleisch, John, Williams, David, Li, Chuanfu

“…Myocardial apoptosis plays an important role in myocardial ischemia/reperfusion (I/R) injury. Activation of PI3K/Akt signaling protects the myocardium from I/R…”
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Cardiovascular Dysfunction in COVID-19: Association Between Endothelial Cell Injury and Lactate by Yang, Kun, Holt, Matthew, Fan, Min, Lam, Victor, Yang, Yong, Ha, Tuanzhu, Williams, David L, Li, Chuanfu, Wang, Xiaohui

“…Coronavirus disease 2019 (COVID-19), an infectious respiratory disease propagated by a new virus known as Severe Acute Respiratory Syndrome Coronavirus-2…”
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Large-scale networks changes in Wilson’s disease associated with neuropsychiatric impairments: a resting-state functional magnetic resonance imaging study by Wang, Anqin, Dong, Ting, Wei, Taohua, Wu, Hongli, Yang, Yulong, Ding, Yufeng, Li, Chuanfu, Yang, Wenming

“…Background In Wilson's disease (WD) patients, network connections across the brain are disrupted, affecting multidomain function. However, the details of this…”
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Endothelial HSPA12B Exerts Protection Against Sepsis-Induced Severe Cardiomyopathy via Suppression of Adhesion Molecule Expression by miR-126 by Zhang, Xia, Wang, Xiaohui, Fan, Min, Tu, Fei, Yang, Kun, Ha, Tuanzhu, Liu, Li, Kalbfleisch, John, Williams, David, Li, Chuanfu

“…Heat shock protein A12B (HSPA12B) is predominately expressed in endothelial cells (ECs) and has been reported to protect against cardiac dysfunction from…”
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Toll-like receptors: new players in myocardial ischemia/reperfusion injury by Ha, Tuanzhu, Liu, Li, Kelley, Jim, Kao, Race, Williams, David, Li, Chuanfu

“…Innate immune and inflammatory responses have been implicated in myocardial ischemia/reperfusion (I/R) injury. However, the mechanisms by which innate immunity…”
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Novel Role of Endothelial Derived Exosomal HSPA12B in Regulating Macrophage Inflammatory Responses in Polymicrobial Sepsis by Tu, Fei, Wang, Xiaohui, Zhang, Xia, Ha, Tuanzhu, Wang, Yana, Fan, Min, Yang, Kun, Gill, P Spencer, Ozment, Tammy R, Dai, Yuan, Liu, Li, Williams, David L, Li, Chuanfu

“…Endothelial cell dysfunction contributes to sepsis induced initiate immune response and the infiltration of immune cells into organs, resulting in organ…”
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HSPA12A controls cerebral lactate homeostasis to maintain hippocampal neurogenesis and mood stabilization by Wang, Jialing, Lu, Ting, Gui, Yali, Zhang, Xiaojin, Cao, Xiaofei, Li, Yuehua, Li, Chuanfu, Liu, Li, Ding, Zhengnian

“…Mood instability, a subjective emotional state defined as rapid mood oscillations of up and down, is a symptom that occurs in several psychiatric disorders,…”
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Structural and Functional Changes Are Related to Cognitive Status in Wilson's Disease by Hu, Sheng, Xu, Chunsheng, Dong, Ting, Wu, Hongli, Wang, Yi, Wang, Anqin, Kan, Hongxing, Li, Chuanfu

“…Patients with Wilson's disease (WD) suffer from prospective memory (PM) impairment, and some of patients develop cognitive impairment. However, very little is…”
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Lactate's impact on immune cells in sepsis: unraveling the complex interplay by Zhang, Tao, Chen, Linjian, Kueth, Gatkek, Shao, Emily, Wang, Xiaohui, Ha, Tuanzhu, Williams, David L, Li, Chuanfu, Fan, Min, Yang, Kun

“…Lactate significantly impacts immune cell function in sepsis and septic shock, transcending its traditional view as just a metabolic byproduct. This review…”
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Simulation of Fluidization Quality for Various Reduced−Gas Composition and Agitation Speed Circumstances in a Gas-Solid Fluidized Bed with an Inclined Agitator by Li, Chuanfu, Liu, Yan, Wu, Yuelong, Li, Xiaolong, Zhang, Tingan

“…Blast furnace ironmaking is one of the most serious carbon dioxide emission processes. To reduce energy consumption and CO2 emissions, fluidized bed ironmaking…”
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HNF4α ubiquitination mediated by Peli1 impairs FAO and accelerates pressure overload-induced myocardial hypertrophy by Hou, Yuxing, Shi, Pengxi, Du, Haiyang, Zhu, Chenghao, Tang, Chao, Que, Linli, Zhu, Guoqing, Liu, Li, Chen, Qi, Li, Chuanfu, Shao, Guoqiang, Li, Yuehua, Li, Jiantao

“…Impaired fatty acid oxidation (FAO) is a prominent feature of metabolic remodeling observed in pathological myocardial hypertrophy. Hepatocyte nuclear factor…”
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Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activation by Song, Juan, Zhu, Yun, Li, Jiantao, Liu, Jiahao, Gao, Yun, Ha, Tuanzhu, Que, Linli, Liu, Li, Zhu, Guoqing, Chen, Qi, Xu, Yong, Li, Chuanfu, Li, Yuehua

“…Abstract Activation of cardiac fibroblasts is a key event in the progression of cardiac fibrosis that leads to heart failure. However, the molecular mechanisms…”
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