Search Results - "CHRISTOPHER, S. R"

Storm Surge and Ponding Explain Mangrove Dieback in Southwest Florida Following Hurricane Irma by Lagomasino, David, Castaneda-Moya, Edward, Cook, Bruce D, Montesano, Paul M, Neigh, Christopher S R, Corp, Lawrence A, Ott, Lesley E, Chavez, Selena, Morton, Douglas C

“…Mangroves buffer inland ecosystems from hurricane winds and storm surge. However, their ability to withstand harsh cyclone conditions depends on plant…”
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Charting cellular differentiation trajectories with Ricci flow by Baptista, Anthony, MacArthur, Ben D., Banerji, Christopher R. S.

“…Complex biological processes, such as cellular differentiation, require intricate rewiring of intra-cellular signalling networks. Previous characterisations…”
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Clinical AI tools must convey predictive uncertainty for each individual patient by Banerji, Christopher R. S., Chakraborti, Tapabrata, Harbron, Chris, MacArthur, Ben D.

“…Artificial intelligence tools usually aim to maximize predictive accuracy, but personalized measures of uncertainty, using new techniques such as conformal…”
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Deep learning as Ricci flow by Baptista, Anthony, Barp, Alessandro, Chakraborti, Tapabrata, Harbron, Chris, MacArthur, Ben D., Banerji, Christopher R. S.

“…Deep neural networks (DNNs) are powerful tools for approximating the distribution of complex data. It is known that data passing through a trained DNN…”
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Pathomechanisms and biomarkers in facioscapulohumeral muscular dystrophy: roles of DUX4 and PAX7 by Banerji, Christopher R S, Zammit, Peter S

“…Facioscapulohumeral muscular dystrophy (FSHD) is characterised by progressive skeletal muscle weakness and wasting. FSHD is linked to epigenetic derepression…”
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PAX7 target genes are globally repressed in facioscapulohumeral muscular dystrophy skeletal muscle by Banerji, Christopher R. S., Panamarova, Maryna, Hebaishi, Husam, White, Robert B., Relaix, Frédéric, Severini, Simone, Zammit, Peter S.

“…Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy, linked to hypomethylation of D4Z4 repeats on chromosome 4q causing expression…”
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The DUX4-HIF1α Axis in Murine and Human Muscle Cells: A Link More Complex Than Expected by Nguyen, Thuy-Hang, Limpens, Maelle, Bouhmidi, Sihame, Paprzycki, Lise, Legrand, Alexandre, Declèves, Anne-Emilie, Heher, Philipp, Belayew, Alexandra, Banerji, Christopher R S, Zammit, Peter S, Tassin, Alexandra

“…FacioScapuloHumeral muscular Dystrophy (FSHD) is one of the most prevalent inherited muscle disorders and is linked to the inappropriate expression of the DUX4…”
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Primary progressive aphasia: six questions in search of an answer by Belder, Christopher R. S., Marshall, Charles R., Jiang, Jessica, Mazzeo, Salvatore, Chokesuwattanaskul, Anthipa, Rohrer, Jonathan D., Volkmer, Anna, Hardy, Chris J. D., Warren, Jason D.

“…Here, we review recent progress in the diagnosis and management of primary progressive aphasia—the language-led dementias. We pose six key unanswered questions…”
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DUX4 induces a transcriptome more characteristic of a less-differentiated cell state and inhibits myogenesis by Knopp, Paul, Krom, Yvonne D, Banerji, Christopher R S, Panamarova, Maryna, Moyle, Louise A, den Hamer, Bianca, van der Maarel, Silvère M, Zammit, Peter S

“…Skeletal muscle wasting in facioscapulohumeral muscular dystrophy (FSHD) results in substantial morbidity. On a disease-permissive chromosome 4qA haplotype,…”
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Desert Locust Cropland Damage Differentiated from Drought, with Multi-Source Remote Sensing in Ethiopia by Alemu, Woubet G, Neigh, Christopher S R

“…In 2020, Ethiopia had the worst desert locust outbreak in 25 years, leading to food insecurity. Locust research has typically focused on predicting the paths…”
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Phylogenetic and functional evidence suggests that deep-ocean ecosystems are highly sensitive to environmental change and direct human disturbance by Ashford, Oliver S, Kenny, Andrew J, Barrio Froján, Christopher R S, Bonsall, Michael B, Horton, Tammy, Brandt, Angelika, Bird, Graham J, Gerken, Sarah, Rogers, Alex D

“…An understanding of the balance of interspecific competition and the physical environment in structuring organismal communities is crucial because those…”
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Cellular network entropy as the energy potential in Waddington's differentiation landscape by Banerji, Christopher R. S., Miranda-Saavedra, Diego, Severini, Simone, Widschwendter, Martin, Enver, Tariq, Zhou, Joseph X., Teschendorff, Andrew E.

“…Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although molecular signatures characterising…”
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The bioclimatic extent and pattern of the cold edge of the boreal forest: the circumpolar taiga-tundra ecotone by Montesano, Paul M, Neigh, Christopher S R, Macander, Matthew, Feng, Min, Noojipady, Praveen

“…Current configurations of forest structure at the cold edge of the boreal may help understand the future of ecosystem functioning in high northern latitudes…”
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An in silico FSHD muscle fiber for modeling DUX4 dynamics and predicting the impact of therapy by Cowley, Matthew V, Pruller, Johanna, Ganassi, Massimo, Zammit, Peter S, Banerji, Christopher R S

“…Facioscapulohumeral muscular dystrophy (FSHD) is an incurable myopathy linked to the over-expression of the myotoxic transcription factor DUX4. Targeting DUX4…”
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Missing pieces to modeling the Arctic-Boreal puzzle by Fisher, Joshua B, Hayes, Daniel J, Schwalm, Christopher R, Huntzinger, Deborah N, Stofferahn, Eric, Schaefer, Kevin, Luo, Yiqi, Wullschleger, Stan D, Goetz, Scott, Miller, Charles E, Griffith, Peter, Chadburn, Sarah, Chatterjee, Abhishek, Ciais, Philippe, Douglas, Thomas A, Genet, Hélène, Ito, Akihiko, Neigh, Christopher S R, Poulter, Benjamin, Rogers, Brendan M, Sonnentag, Oliver, Tian, Hanqin, Wang, Weile, Xue, Yongkang, Yang, Zong-Liang, Zeng, Ning, Zhang, Zhen

“…NASA has launched the decade-long Arctic-Boreal Vulnerability Experiment (ABoVE). While the initial phases focus on field and airborne data collection, early…”
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Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer by Banerji, Christopher R S, Severini, Simone, Caldas, Carlos, Teschendorff, Andrew E

“…The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted…”
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Calibration of Maxar Constellation Over Libya-4 Site Using MAIAC Technique by Choi, Myungje, Lyapustin, Alexei, Wang, Yujie, Tucker, Compton J., Khan, Maudood N., Policelli, Frederick, Neigh, Christopher S. R., Hall, Alfreda A.

“…The very high resolution commercial satellite constellation of Maxar offers unique opportunities for a wide range of Earth science research and applications…”
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Patterns of regional site index across a North American boreal forest gradient by Montesano, Paul M, Neigh, Christopher S R, Macander, Matthew J, Wagner, William, Duncanson, Laura I, Wang, Panshi, Sexton, Joseph O, Miller, Charles E, Armstrong, Amanda H

“…Forest structure—the height, cover, vertical complexity, and spatial patterns of trees—is a key indicator of productivity variation across forested extents…”
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Aortic Stenosis in Dialysis Patients by Ahmad, Yousif, Bellamy, Michael F., Baker, Christopher S. R.

“…Aortic valve stenosis occurs 10–20 years earlier in patients on dialysis compared with the general population. This is likely related to the exposure of the…”
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Investigating the environmental drivers of deep‐seafloor biodiversity: A case study of peracarid crustacean assemblages in the Northwest Atlantic Ocean by Ashford, Oliver S., Kenny, Andrew J., Barrio Froján, Christopher R. S., Horton, Tammy, Rogers, Alex D.

“…The deep‐sea benthos covers over 90% of seafloor area and hosts a great diversity of species which contribute toward essential ecosystem services. Evidence…”
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