Search Results - "CHOYKE, Peter L"

Nanodrug Delivery: Is the Enhanced Permeability and Retention Effect Sufficient for Curing Cancer? by Nakamura, Yuko, Mochida, Ai, Choyke, Peter L, Kobayashi, Hisataka

“…Nanotechnology offers several attractive design features that have prompted its exploration for cancer diagnosis and treatment. Nanosized drugs have a large…”
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Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target? by Kobayashi, Hisataka, Watanabe, Rira, Choyke, Peter L

“…Nano-sized therapeutic agents have several advantages over low molecular weight agents such as a larger loading capacity, the ability to protect the payload…”
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Target-Cancer-Cell-Specific Activatable Fluorescence Imaging Probes: Rational Design and in Vivo Applications by Kobayashi, Hisataka, Choyke, Peter L

“…Conventional imaging methods, such as angiography, computed tomography (CT), magnetic resonance imaging (MRI), and radionuclide imaging, rely on contrast…”
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Near-infrared photoimmunotherapy of cancer: a new approach that kills cancer cells and enhances anti-cancer host immunity by Kobayashi, Hisataka, Furusawa, Aki, Rosenberg, Adrian, Choyke, Peter L

“…Abstract Near-infrared photoimmunotherapy (NIR-PIT) is a recently developed hybrid cancer therapy that directly kills cancer cells as well as producing a…”
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Super enhanced permeability and retention (SUPR) effects in tumors following near infrared photoimmunotherapy by Kobayashi, Hisataka, Choyke, Peter L

“…To date, the delivery of nano-sized therapeutic agents to cancers largely relies on enhanced permeability and retention (EPR) effects that are caused by the…”
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Fluorescence-Guided Surgery by Nagaya, Tadanobu, Nakamura, Yu A, Choyke, Peter L, Kobayashi, Hisataka

“…Surgical resection of cancer remains an important treatment modality. Despite advances in preoperative imaging, surgery itself is primarily guided by the…”
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Cancer-Associated Fibroblasts: Tumorigenicity and Targeting for Cancer Therapy by Glabman, Raisa A, Choyke, Peter L, Sato, Noriko

“…Cancer-associated fibroblasts (CAFs) are a heterogenous group of activated fibroblasts and a major component of the tumor stroma. CAFs may be derived from…”
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Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats by Longmire, Michelle, Choyke, Peter L, Kobayashi, Hisataka

“…Nanoparticles possess enormous potential as diagnostic imaging agents and hold promise for the development of multimodality agents with both imaging and…”
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Cancer cell–selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules by Mitsunaga, Makoto, Ogawa, Mikako, Kosaka, Nobuyuki, Rosenblum, Lauren T, Choyke, Peter L, Kobayashi, Hisataka

“…Makoto Mitsunaga et al . have developed a new form of molecular-targeted cancer therapy that provides an alternative to current photodynamic approaches where…”
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Prostate cancer – major changes in the American Joint Committee on Cancer eighth edition cancer staging manual by Buyyounouski, Mark K., Choyke, Peter L., McKenney, Jesse K., Sartor, Oliver, Sandler, Howard M., Amin, Mahul B., Kattan, Michael W., Lin, Daniel W.

“…Answer questions and earn CME/CNE The eighth edition of the American Joint Committee on Cancer (AJCC) tumor‐node‐metastasis (TNM) Staging Manual has been…”
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Near-Infrared Photoimmunotherapy: Photoactivatable Antibody–Drug Conjugates (ADCs) by Kobayashi, Hisataka, Griffiths, Gary L, Choyke, Peter L

“…Cancer treatment has been founded traditionally on the three approaches of surgery, radiation, and chemotherapy with the latter recognized as the obvious…”
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Photoimmunotherapy of gastric cancer peritoneal carcinomatosis in a mouse model by Sato, Kazuhide, Choyke, Peter L, Kobayashi, Hisataka

“…Photoimmunotherapy (PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with the toxicity induced by…”
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Impact of 68Ga-FAPI PET/CT Imaging on the Therapeutic Management of Primary and Recurrent Pancreatic Ductal Adenocarcinomas by Röhrich, Manuel, Naumann, Patrick, Giesel, Frederik L, Choyke, Peter L, Staudinger, Fabian, Wefers, Annika, Liew, Dawn P, Kratochwil, Clemens, Rathke, Hendrik, Liermann, Jakob, Herfarth, Klaus, Jäger, Dirk, Debus, Jürgen, Haberkorn, Uwe, Lang, Matthias, Koerber, Stefan A

“…Pancreatic ductal carcinoma (PDAC) is a highly lethal cancer, and early detection and accurate staging are critical to prolonging survival. PDAC typically has…”
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PSMA PET and Radionuclide Therapy in Prostate Cancer by Bouchelouche, Kirsten, MD, DMSc, Turkbey, Baris, MD, FSAR, Choyke, Peter L., MD FACR

“…Prostate cancer (PCa) is the most common malignancy in men and a major cause of cancer death. Accurate imaging plays an important role in diagnosis, staging,…”
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Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple Negative Breast Cancer: Optimizing the Conjugate-Light Regimen by Nagaya, Tadanobu, Sato, Kazuhide, Harada, Toshiko, Nakamura, Yuko, Choyke, Peter L, Kobayashi, Hisataka

“…Triple-negative breast cancer (TNBC) is considered one of the most aggressive subtypes of breast cancer. Near infrared photoimmunotherapy (NIR-PIT) is a cancer…”
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What Are We Missing? False-Negative Cancers at Multiparametric MR Imaging of the Prostate by Borofsky, Samuel, George, Arvin K, Gaur, Sonia, Bernardo, Marcelino, Greer, Matthew D, Mertan, Francesca V, Taffel, Myles, Moreno, Vanesa, Merino, Maria J, Wood, Bradford J, Pinto, Peter A, Choyke, Peter L, Turkbey, Baris

“…Purpose To characterize clinically important prostate cancers missed at multiparametric (MP) magnetic resonance (MR) imaging. Materials and Methods The local…”
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A Grading System for the Assessment of Risk of Extraprostatic Extension of Prostate Cancer at Multiparametric MRI by Mehralivand, Sherif, Shih, Joanna H, Harmon, Stephanie, Smith, Clayton, Bloom, Jonathan, Czarniecki, Marcin, Gold, Samuel, Hale, Graham, Rayn, Kareem, Merino, Maria J, Wood, Bradford J, Pinto, Peter A, Choyke, Peter L, Turkbey, Baris

“…Purpose To evaluate MRI features associated with pathologically defined extraprostatic extension (EPE) of prostate cancer and to propose an MRI grading system…”
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Near Infrared Photoimmunotherapy; A Review of Targets for Cancer Therapy by Kato, Takuya, Wakiyama, Hiroaki, Furusawa, Aki, Choyke, Peter L., Kobayashi, Hisataka

“…Near-infrared photoimmunotherapy (NIR-PIT) is a newly developed cancer treatment that uses an antibody-photoabsorber (IRDye700DX) conjugate (APC) that is…”
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Activatable fluorescent probes in fluorescence-guided surgery: Practical considerations by Mochida, Ai, Ogata, Fusa, Nagaya, Tadanobu, Choyke, Peter L., Kobayashi, Hisataka

“…[Display omitted] Fluorescence-guided imaging during surgery is a promising technique that is increasingly used to aid surgeons in identifying sites of tumor…”
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Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals by Kobayashi, Hisataka, Longmire, Michelle R, Ogawa, Mikako, Choyke, Peter L

“…In recent years, numerous in vivo molecular imaging probes have been developed. As a consequence, much has been published on the design and synthesis of…”
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