Search Results - "CHOWIENCZYK, Philip"

Estimating pulse wave velocity from the radial pressure wave using machine learning algorithms by Jin, Weiwei, Chowienczyk, Philip, Alastruey, Jordi

“…One of the European gold standard measurement of vascular ageing, a risk factor for cardiovascular disease, is the carotid-femoral pulse wave velocity (cfPWV),…”
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Do anti‐tumour necrosis factor‐α biologics affect subclinical measures of atherosclerosis and arteriosclerosis? A systematic review by Knowles, Laurence, Nadeem, Nida, Chowienczyk, Philip J.

“…Aims: Inflammatory cytokines, particularly tumour necrosis factor‐α (TNFα), are thought to promote arterial disease through a variety of mechanisms leading to…”
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Prospective Study on Circulating MicroRNAs and Risk of Myocardial Infarction by Zampetaki, Anna, PhD, Willeit, Peter, MD, MPhil, Tilling, Lindsey, MD, Drozdov, Ignat, MPhil, Prokopi, Marianna, PhD, Renard, Jean-Marie, PhD, Mayr, Agnes, MD, Weger, Siegfried, MD, Schett, Georg, MD, Shah, Ajay, MD, FMedSci, Boulanger, Chantal M., PhD, Willeit, Johann, MD, Chowienczyk, Philip J., MD, Kiechl, Stefan, MD, Mayr, Manuel, MD, PhD

“…Objectives This study sought to explore the association between baseline levels of microRNAs (miRNAs) (1995) and incident myocardial infarction (1995 to 2005)…”
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Effects of potassium supplementation on plasma aldosterone: a systematic review and meta-analysis in humans by McNally, Ryan J, Farukh, Bushra, Chowienczyk, Philip J, Faconti, Luca

“…Effects of potassium supplementation on blood pressure (BP) may be offset by an increase in plasma aldosterone. The magnitude of potassium-dependent regulation…”
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Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta‐analysis by McNally, Ryan J., Farukh, Bushra, Chowienczyk, Philip J., Faconti, Luca

“…Aim By contrast with drugs inhibiting the renin‐angiotensin‐aldosterone system (RAAS), diuretics stimulate renin release by the kidneys. Although plasma…”
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Aortic Stiffness and Disease: Location is Key by Chowienczyk, Philip J

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Neuronal nitric oxide synthase regulates regional brain perfusion in healthy humans by O’Gallagher, Kevin, Puledda, Francesca, O’Daly, Owen, Ryan, Matthew, Dancy, Luke, Chowienczyk, Philip J, Zelaya, Fernando, Goadsby, Peter J, Shah, Ajay M

“…Abstract Aims Neuronal nitric oxide synthase (nNOS) is highly expressed within the cardiovascular and nervous systems. Studies in genetically modified mice…”
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Reduced First-Phase Ejection Fraction and Sustained Myocardial Wall Stress in Hypertensive Patients With Diastolic Dysfunction: A Manifestation of Impaired Shortening Deactivation That Links Systolic to Diastolic Dysfunction and Preserves Systolic Ejection Fraction by Gu, Haotian, Li, Ye, Fok, Henry, Simpson, John, Kentish, Jonathan C, Shah, Ajay M, Chowienczyk, Philip J

“…Impaired shortening deactivation of cardiac myocytes could sustain myocardial contraction, preserving ejection fraction at the expense of diastolic…”
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A review of the prescribing trend of thiazide‐type and thiazide‐like diuretics in hypertension: A UK perspective by McNally, Ryan J., Morselli, Franca, Farukh, Bushra, Chowienczyk, Philip J., Faconti, Luca

“…Thiazide diuretics have been the cornerstone of hypertension treatment for >5 decades. Most recent European and American guidelines recommend both…”
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Uncertain Etiology of Left Ventricular Hypertrophy in a Young Subject With Hypertension Treated With Dexamphetamine by Morselli, Franca, Fang, Lingyun, Ambrosini, Ilaria, Chowienczyk, Philip J., Faconti, Luca

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Snacking on Whole Almonds for Six Weeks Increases Heart Rate Variability during Mental Stress in Healthy Adults: A Randomized Controlled Trial by Dikariyanto, Vita, Smith, Leanne, Chowienczyk, Philip J, Berry, Sarah E, Hall, Wendy L

“…Cardiac autonomic regulation can be indirectly measured by heart rate variability (HRV). Low HRV, which can be induced by mental stress, is a predictor of risk…”
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Snacking on whole almonds for 6 weeks improves endothelial function and lowers LDL cholesterol but does not affect liver fat and other cardiometabolic risk factors in healthy adults: the ATTIS study, a randomized controlled trial by Dikariyanto, Vita, Smith, Leanne, Francis, Lucy, Robertson, May, Kusaslan, Eslem, O’Callaghan-Latham, Molly, Palanche, Camille, D’Annibale, Maria, Christodoulou, Dimitra, Basty, Nicolas, Whitcher, Brandon, Shuaib, Haris, Charles-Edwards, Geoffrey, Chowienczyk, Philip J, Ellis, Peter R, Berry, Sarah EE, Hall, Wendy L

“…There is convincing evidence that daily whole almond consumption lowers blood LDL cholesterol concentrations, but effects on other cardiometabolic risk factors…”
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Resistant hypertension, catecholamine excess, left ventricular hypertrophy and systolic dysfunction: hypertensive cardiomyopathy? by Gould, Allon, Ambrosini, Ilaria, Masci, Pier-Giorgio, Mcnally, Ryan John, Chowienczyk, Philip J., Faconti, Luca

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Contour analysis of the photoplethysmographic pulse measured at the finger by Millasseau, Sandrine C, Ritter, James M, Takazawa, Kenji, Chowienczyk, Philip J

“…Analysis of the contour of the peripheral pulse to assess arterial properties was first described in the nineteenth century. With the recognition of the…”
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Impact of arterio–ventricular interaction on first-phase ejection fraction in aortic stenosis by Einarsen, Eigir, Hjertaas, Johannes J, Gu, Haotian, Matre, Knut, Chowienczyk, Philip J, Gerdts, Eva, Chambers, John B, Saeed, Sahrai

“…Abstract Aims  First-phase ejection fraction (EF1), the EF at the time to peak aortic jet velocity, has been proposed as a novel marker of peak systolic…”
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Effect of diuretics on plasma renin activity in primary hypertension: A systematic review and meta‐analysis by McNally, Ryan J., Faconti, Luca, Cecelja, Marina, Farukh, Bushra, Floyd, Christopher N., Chowienczyk, Philip J.

“…Aims Plasma renin activity (PRA) is regarded as a marker of sodium and fluid homeostasis in patients with primary hypertension. Whether effects of diuretics on…”
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Blood Pressure in Healthy Humans Is Regulated by Neuronal NO Synthase by Shabeeh, Husain, Khan, Sitara, Jiang, Benyu, Brett, Sally, Melikian, Narbeh, Casadei, Barbara, Chowienczyk, Philip J, Shah, Ajay M

“…NO is physiologically generated by endothelial and neuronal NO synthase (nNOS) isoforms. Although nNOS was first identified in brain, it is expressed in other…”
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The Effect of a Neuronal Nitric Oxide Synthase Inhibitor on Neurovascular Regulation in Humans by O’Gallagher, Kevin, Rosentreter, Ryan E., Elaine Soriano, Jan, Roomi, Ali, Saleem, Saqib, Lam, Tyler, Roy, Roman, Gordon, Grant R., Raj, Satish R., Chowienczyk, Philip J., Shah, Ajay M., Phillips, Aaron A.

“…Neurovascular coupling (NVC) is a key process in cerebral blood flow regulation. NVC ensures adequate brain perfusion to changes in local metabolic demands…”
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Dietary nitrate prevents progression of carotid subclinical atherosclerosis through blood pressure‐independent mechanisms in patients with or at risk of type 2 diabetes mellitus by Morselli, Franca, Faconti, Luca, Mills, Charlotte E., Morant, Steven, Chowienczyk, Philip J., Yeung, Joshua Au, Cavarape, Alessandro, Cruickshank, J. Kennedy, Webb, Andrew J.

“…Aims To test if 6 months' intervention with dietary nitrate and spironolactone could affect carotid subclinical atherosclerosis and stiffness, respectively,…”
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Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells by Tilling, Lindsey, Chowienczyk, Philip, Clapp, Brian

“…Endothelial progenitor cells are a population of bone marrow‐derived mononuclear cells thought to engage in endothelial repair and hence are considered…”
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