Search Results - "CHOWDHURY, Wasim H"

Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights by Watson, Amanda, Shah, Pankil, Lee, Doug, Liang, Sitai, Joshi, Geeta, Metitiri, Ediri, Chowdhury, Wasim H, Bacich, Dean, Dube, Peter, Xiang, Yan, Hanley, Daniel, Martinez-Sobrido, Luis, Rodriguez, Ronald

“…The SARS-CoV-2 pandemic has caused unprecedented worldwide infections from persistent mutant variants with various degrees of infectivity and virulence. The…”
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Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening by Kumar, Binod, Khaleghzadegan, Salar, Mears, Brian, Hatano, Koji, Kudrolli, Tarana A, Chowdhury, Wasim H, Yeater, David B, Ewing, Charles M, Luo, Jun, Isaacs, William B, Marchionni, Luigi, Lupold, Shawn E

“…The Androgen Receptor (AR) plays a key role in prostate biology and in the progression of prostate cancer (PCa) to castration resistance. The role of microRNAs…”
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XBSeq2: a fast and accurate quantification of differential expression and differential polyadenylation by Liu, Yuanhang, Wu, Ping, Zhou, Jingqi, Johnson-Pais, Teresa L, Lai, Zhao, Chowdhury, Wasim H, Rodriguez, Ronald, Chen, Yidong

“…RNA sequencing (RNA-seq) is a high throughput technology that profiles gene expression in a genome-wide manner. RNA-seq has been mainly used for testing…”
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Characterization of a novel metastatic prostate cancer cell line of LNCaP origin by Castanares, Mark A., Copeland, Ben T., Chowdhury, Wasim H., Liu, Minzhi M., Rodriguez, Ronald, Pomper, Martin G., Lupold, Shawn E., Foss, Catherine A.

“…BACKGROUND The LNCaP cell line was originally isolated from the lymph node of a patient with metastatic prostate cancer. Many cell lines have been derived from…”
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A real time Metridia luciferase based non-invasive reporter assay of mammalian cell viability and cytotoxicity via the β-actin promoter and enhancer by Lupold, Shawn E, Johnson, Tamara, Chowdhury, Wasim H, Rodriguez, Ronald

“…Secreted reporter molecules offer a means to evaluate biological processes in real time without the need to sacrifice samples at pre-determined endpoints. Here…”
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Cyclophosphamide unmasks an antimetastatic effect of local tumor cryoablation by Levy, Moshe Yair, Sidana, Abhinav, Chowdhury, Wasim H, Solomon, Steven B, Drake, Charles G, Rodriguez, Ronald, Fuchs, Ephraim J

“…Cryoablation of a solitary tumor mass releases intact tumor antigens and can induce protective antitumor immunity but has limited efficacy in the treatment of…”
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Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells in vitro and in vivo by Kortenhorst, Madeleine S Q, Isharwal, Sumit, van Diest, Paul J, Chowdhury, Wasim H, Marlow, Cameron, Carducci, Michael A, Rodriguez, Ronald, Veltri, Robert W

“…Histone deacetylase inhibitors such as valproic acid (VPA) are promising anticancer agents that change the acetylation status of histones and loosen the…”
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Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells by Chen, Chien-Lun, Sung, Jennifer, Cohen, Michael, Chowdhury, Wasim H, Sachs, Markus D, Li, Ying, Lakshmanan, Yegappan, Yung, Benjamin Y M, Lupold, Shawn E, Rodriguez, Ronald

“…Histone deacetylase inhibitors (HDACIs) represent a promising new class of antineoplastic agents that affect proliferation, differentiation, and apoptosis in…”
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miR-21: An Androgen Receptor-Regulated MicroRNA that Promotes Hormone-Dependent and Hormone-Independent Prostate Cancer Growth by RIBAS, Judit, XIAOHUA NI, MENDELL, Joshua T, LUPOLD, Shawn E, HAFFNER, Michael, WENTZEL, Erik A, HASSANZADEH SALMASI, Amirali, CHOWDHURY, Wasim H, KUDROLLI, Tarana A, YEGNASUBRAMANIAN, Srinivasan, LUDO, Jun, RODRIGUEZ, Ron

“…Androgen receptor (AR)-mediated oncogenic pathways have not been fully elucidated. In this study, we used high-throughput microarray analysis on two…”
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Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts by Ni, Xiaohua, Zhang, Yonggang, Ribas, Judit, Chowdhury, Wasim H, Castanares, Mark, Zhang, Zhewei, Laiho, Marikki, DeWeese, Theodore L, Lupold, Shawn E

“…Dose-escalated radiation therapy for localized prostate cancer (PCa) has a clear therapeutic benefit; however, escalated doses may also increase injury to…”
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A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation by Hatano, Koji, Kumar, Binod, Zhang, Yonggang, Coulter, Jonathan B, Hedayati, Mohammad, Mears, Brian, Ni, Xiaohua, Kudrolli, Tarana A, Chowdhury, Wasim H, Rodriguez, Ronald, DeWeese, Theodore L, Lupold, Shawn E

“…MicroRNAs (miRNAs) have been implicated in DNA repair pathways through transcriptional responses to DNA damaging agents or through predicted miRNA regulation…”
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Prostate stem cell antigen enhancer and uroplakin II promoter based bladder cancer targeted tissue-specific vector by Wang, Degui, Ph.D, Wang, Zhiping, Ph.D, Tian, Junqiang, Ph.D, He, Xiangdong, Ph.D, Chowdhury, Wasim H., M.S, Zhang, Xiangbo, Ph.D, Li, Shigang, Ph.D, Rodriguez, Ronald, M.D., Ph.D

“…Abstract Purpose To construct a dual specific vector which contains prostate stem cell antigen enhancer (PSCAE) and uroplakin II (UPII) promoter targeted…”
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Pathological downstaging following radical cystectomy for muscle-invasive bladder cancer: Survival outcomes in the setting of neoadjuvant chemotherapy versus transurethral resection only by Cajipe, Miguel, Wang, Hanzhang, Elshabrawy, Ahmed, Kaushik, Dharam, Liss, Michael, Svatek, Robert, Wu, Shenghui, Chowdhury, Wasim H., Ramamurthy, Chethan, Mansour, Ahmed M.

“…•Neoadjuvant chemotherapy for muscle invasive bladder cancer offers survival benefit.•This survival benefit was still noticed even in patients who achieve…”
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Real-time, near-infrared fluorescence imaging with an optimized dye/light source/camera combination for surgical guidance of prostate cancer by Neuman, Brian P, Eifler, John B, Castanares, Mark, Chowdhury, Wasim H, Chen, Ying, Mease, Ronnie C, Ma, Rong, Mukherjee, Amarnath, Lupold, Shawn E, Pomper, Martin G, Rodriguez, Ronald

“…The prostate-specific membrane antigen (PSMA) is a surface glycoprotein overexpressed on malignant prostate cells, as well as in the neovasculature of many…”
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Increased expression of TRIP13 drives the tumorigenesis of bladder cancer in association with the EGFR signaling pathway by Gao, Yanjun, Liu, Shanhui, Guo, Qi, Zhang, Su, Zhao, Youli, Wang, Hanzhang, Li, Tianbao, Gong, Yuwen, Wang, Yuhan, Zhang, Tao, Dong, Zhilong, Bacich, Dean, Chowdhury, Wasim H, Rodriguez, Ronald, Wang, Zhiping

“…Thyroid hormone receptor interactor 13 (TRIP13) is a crucial regulator of the spindle apparatus checkpoint and double-stranded break repair. The abnormal…”
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Evaluation of prostate-specific membrane antigen as an imaging reporter by Castanares, Mark A, Mukherjee, Amarnath, Chowdhury, Wasim H, Liu, Minzhi, Chen, Ying, Mease, Ronnie C, Wang, Yuchuan, Rodriguez, Ronald, Lupold, Shawn E, Pomper, Martin G

“…Genetic reporters provide a noninvasive method to monitor and evaluate a population of cells. The ideal properties of a gene reporter-probe system include…”
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PD37-08 ENHANCING THE EFFICACY OF VALPROIC ACID IN PROSTATE CANCER CELLS WITH NUTRITIONAL SUPPLEMENTS by Chowdhury, Wasim H, O'James, Anna-Barbara, Sidana, Abhinav, Goyal, Jatindar, Oh, Daniel, Todd, Grace I, Rahman, Mizanur, Rodriguez, Ronald

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National Trends and Impact of Regionalization of Radical Cystectomy on Survival Outcomes in Patients with Muscle Invasive Bladder Cancer by Herrera, Juan C., Ibilibor, Christine, Wang, Hanzhang, Klein, Geraldine T., Elshabrawy, Ahmed, Chowdhury, Wasim H., Kaushik, Dharam, Liss, Michael, Svatek, Robert, Mansour, Ahmed M.

“…To evaluate national trends and the effect of surgical volume on perioperative mortality and overall survival (OS)in patients undergoing radical cystectomy…”
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Cryoimmunotherapy in Urologic Oncology by Sidana, Abhinav, Chowdhury, Wasim H, Fuchs, Ephraim J, Rodriguez, Ronald

“…Cryoablation is gaining acceptance as a primary treatment of localized as well as a salvage therapy of metastatic urologic malignancies. Anecdotal clinical…”
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Loss of Cyclin-Dependent Kinase Inhibitor Alters Oncolytic Adenovirus Replication and Promotes More Efficient Virus Production by Höti, Naseruddin, Johnson, Tamara Jane, Chowdhury, Wasim H, Rodriguez, Ronald

“…We elucidate the role of p21/Waf-1, a cyclin-dependent kinase inhibitor, on the oncolytic infection and replication cycle of adenovirus by studying both mRNA…”
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