Search Results - "CHOUDRY, G. A"

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  1. 1

    A novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9 by CHOUDRY, G. A, STEWART, P. A, DOUBLE, J. A, KRUL, M. R. L, NAYLOR, B, FLANNIGAN, G. M, SHAH, T. K, BROWN, J. E, PHILLIPS, R. M

    Published in British journal of cancer (19-10-2001)
    “…The indolequinone EO9 demonstrated good preclinical activity but failed to show clinical efficacy against a range of tumours following intravenous drug…”
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    Journal Article
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    Bioreductive Activation of a Series of Indolequinones by Human DT-Diaphorase:  Structure−Activity Relationships by Phillips, Roger M, Naylor, Matthew A, Jaffar, Mohammed, Doughty, Stephen W, Everett, Steven A, Breen, Anthony G, Choudry, Guzanfar A, Stratford, Ian J

    Published in Journal of medicinal chemistry (07-10-1999)
    “…A series of indolequinones including derivatives of EO9 bearing various functional groups and related indole-2-carboxamides have been studied with a view to…”
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    Journal Article