Search Results - "CHOU, David B"

Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut by Praveschotinunt, Pichet, Duraj-Thatte, Anna M., Gelfat, Ilia, Bahl, Franziska, Chou, David B., Joshi, Neel S.

“…Mucosal healing plays a critical role in combatting the effects of inflammatory bowel disease, fistulae and ulcers. While most treatments for such diseases…”
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Essential Role for Retinoic Acid in the Promotion of CD4+ T Cell Effector Responses via Retinoic Acid Receptor Alpha by Hall, Jason A., Cannons, Jennifer L., Grainger, John R., Dos Santos, Liliane M., Hand, Timothy W., Naik, Shruti, Wohlfert, Elizabeth A., Chou, David B., Oldenhove, Guillaume, Robinson, Melody, Grigg, Michael E., Kastenmayer, Robin, Schwartzberg, Pamela L., Belkaid, Yasmine

“…Vitamin A and its metabolite, retinoic acid (RA) are implicated in the regulation of immune homeostasis via the peripheral induction of regulatory T cells…”
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Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites by Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Geirnaert, Annelies, Prantil-Baun, Rachelle, Camacho, Diogo M, Chou, David B, Jalili-Firoozinezhad, Sasan, de Wouters, Tomás, Kasendra, Magdalena, Super, Michael, Cartwright, Mark J, Richmond, Camilla A, Breault, David T, Lacroix, Christophe, Ingber, Donald E

“…Species-specific differences in tolerance to infection are exemplified by the high susceptibility of humans to enterohemorrhagic Escherichia coli (EHEC)…”
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Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors by Chou, David B., Furlong, Brooke A., Posey, Ryan R., Kyprianou, Christos, O’Sullivan, Lucy R., David, Rhiannon, Randle, Suzanne J., Polanska, Urszula M., Travers, Jon, Urosevic, Jelena, Hutchinson, John N., Che, Jianwei, Howley, Anna M., Hasserjian, Robert P., Prantil-Baun, Rachelle, Ingber, Donald E.

“…Drug-induced cytopenias are a prevalent and significant issue that worsens clinical outcomes and hinders the effective treatment of cancer. While reductions in…”
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Stromal-derived IL-6 alters the balance of myeloerythroid progenitors during Toxoplasma gondii infection by Chou, David B., Sworder, Brian, Bouladoux, Nicolas, Roy, Cindy N., Uchida, Amiko M., Grigg, Michael, Robey, Pamela G., Belkaid, Yasmine

“…BMSCs are critical regulators of the hematopoietic response to inflammation through secretion of IL‐6. Inflammation alters hematopoiesis, often by decreasing…”
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Inflammatory and MicroRNA Gene Expression as Prognostic Classifier of Barrett's-Associated Esophageal Adenocarcinoma by GIANG HUONG NGUYEN, SCHETTER, Aaron J, HAGIWARA, Nobutoshi, XIN WEI WANG, MIYASHITA, Masao, CASSON, Alan G, HARRIS, Curtis C, CHOU, David B, BOWMAN, Elise D, RONGHUA ZHAO, HAWKES, Jason E, MATHE, Ewy A, KUMAMOTO, Kensuke, YIQIANG ZHAO, BUDHU, Anuradha

“…Esophageal cancer is one of the most aggressive and deadly forms of cancer; highlighting the need to identify biomarkers for early detection and prognostic…”
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Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology by Sontheimer-Phelps, Alexandra, Chou, David B., Tovaglieri, Alessio, Ferrante, Thomas C., Duckworth, Taylor, Fadel, Cicely, Frismantas, Viktoras, Sutherland, Arlene D., Jalili-Firoozinezhad, Sasan, Kasendra, Magdalena, Stas, Eric, Weaver, James C., Richmond, Camilla A., Levy, Oren, Prantil-Baun, Rachelle, Breault, David T., Ingber, Donald E.

“…The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure contribute to intestinal…”
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On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology by Chou, David B., Frismantas, Viktoras, Milton, Yuka, David, Rhiannon, Pop-Damkov, Petar, Ferguson, Douglas, MacDonald, Alexander, Vargel Bölükbaşı, Özge, Joyce, Cailin E., Moreira Teixeira, Liliana S., Rech, Arianna, Jiang, Amanda, Calamari, Elizabeth, Jalili-Firoozinezhad, Sasan, Furlong, Brooke A., O’Sullivan, Lucy R., Ng, Carlos F., Choe, Youngjae, Marquez, Susan, Myers, Kasiani C., Weinberg, Olga K., Hasserjian, Robert P., Novak, Richard, Levy, Oren, Prantil-Baun, Rachelle, Novina, Carl D., Shimamura, Akiko, Ewart, Lorna, Ingber, Donald E.

“…The inaccessibility of living bone marrow (BM) hampers the study of its pathophysiology under myelotoxic stress induced by drugs, radiation or genetic…”
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Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology by Chou, David B., Frismantas, Viktoras, Milton, Yuka, David, Rhiannon, Pop-Damkov, Petar, Ferguson, Douglas, MacDonald, Alexander, Vargel Bölükbaşı, Özge, Joyce, Cailin E., Moreira Teixeira, Liliana S., Rech, Arianna, Jiang, Amanda, Calamari, Elizabeth, Jalili-Firoozinezhad, Sasan, Furlong, Brooke A., O’Sullivan, Lucy R., Ng, Carlos F., Choe, Youngjae, Marquez, Susan, Myers, Kasiani C., Weinberg, Olga K., Hasserjian, Robert P., Novak, Richard, Levy, Oren, Prantil-Baun, Rachelle, Novina, Carl D., Shimamura, Akiko, Ewart, Lorna, Ingber, Donald E.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Sa2028 MATERNAL HORMONE-ASSOCIATED INFLAMMATORY BOWEL DISEASE PROGRESSION IN HUMAN ORGAN CHIPS by Ozkan, Alican, Stejskalova, Anna, Calderon, Karina, Chou, David B., Ferri, Lorenzo E., Ricciardi, Rocco, Bordeianou, Liliana G., Goyal, Girija, Ingber, Donald

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878 MODELING INFLAMMATORY BOWEL DISEASE PROGRESSION IN HUMAN ORGAN-CHIPS by Ozkan, Alican, Merry, Gwenn, Chou, David B., Horvath, Viktor, Ferri, Lorenzo E., Ricciardi, Rocco, Bordeianou, Liliana G., Hall, Sean, Ingber, Donald

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Changes in ABC Transporter Expression during Hematopoiesis Cause Lineage-Biased Cytopenias in Patients Treated with Aurora Kinase Inhibitors by Furlong, Brooke A., Posey, Ryan R., Chou, David B., Kyprianou, Christos, O'Sullivan, Lucy R., David, Rhiannon, Randle, Suzanne, Polanska, Urszula, Urosevic, Jelena, Travers, Jon, Hutchinson, John, Hasserjian, Robert P., Prantil-Baun, Rachelle, Ingber, Donald E.

“…Chemotherapy-induced cytopenias are a prevalent and significant issue that worsens clinical outcomes and hinders the effective treatment of cancer. While they…”
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Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and PhysiologySummary by Alexandra Sontheimer-Phelps, David B. Chou, Alessio Tovaglieri, Thomas C. Ferrante, Taylor Duckworth, Cicely Fadel, Viktoras Frismantas, Arlene D. Sutherland, Sasan Jalili-Firoozinezhad, Magdalena Kasendra, Eric Stas, James C. Weaver, Camilla A. Richmond, Oren Levy, Rachelle Prantil-Baun, David T. Breault, Donald E. Ingber

“…Background & Aims: The mucus layer in the human colon protects against commensal bacteria and pathogens, and defects in its unique bilayered structure…”
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Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma by Nguyen, Giang Huong, Schetter, Aaron J., Chou, David B., Bowman, Elise D., Zhao, Ronghua, Hawkes, Jason E., Mathe, Ewy A., Kumamoto, Kensuke, Zhao, Yiqiang, Budhu, Anuradha, Hagiwara, Nobutoshi, Wang, Xin Wei, Miyashita, Masao, Casson, Alan G., Harris, Curtis C.

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A systematic analysis of global anaemia burden between 1990 and 2010 by Kassebaum, Nicholas J, MD, Jasrasaria, Rashmi, BA, Johns, Nicole, BA, Wulf, Sarah, MPH, Chou, David, BA, Lozano, Rafael, Prof, Naghavi, Mohsen, PhD, Murray, Christopher JL, Prof

“…Abstract Background Anaemia is associated with increased maternal and neonatal mortality, with young children most at risk of developing long-term…”
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