Search Results - "CHOPRA, Abha"
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1
Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
Published in PLoS pathogens (01-09-2011)“…Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that…”
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2
Cytomegalovirus (CMV) Epitope-Specific CD4 + T Cells Are Inflated in HIV + CMV + Subjects
Published in The Journal of immunology (1950) (01-11-2017)“…Select CMV epitopes drive life-long CD8 T cell memory inflation, but the extent of CD4 memory inflation is poorly studied. CD4 T cells specific for human CMV…”
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3
Association of KIR2DL5, KIR2DS5, and KIR2DS1 allelic variation and atopic dermatitis
Published in Scientific reports (31-01-2023)“…Natural killer cells (NK) have been associated with the pathophysiology of atopic dermatitis (AD). NK function is regulated by killer cell Ig-like receptor…”
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4
Comparison of in vitro growth characteristics of Cryptosporidium hominis (IdA15G1) and Cryptosporidium parvum (Iowa-IIaA17G2R1 and IIaA18G3R1)
Published in Parasitology research (1987) (01-12-2023)“…Cryptosporidium is a major cause of diarrhoeal disease and mortality in young children in resource-poor countries, for which no vaccines or adequate…”
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5
Tumor Infiltrating Effector Memory Antigen-Specific CD8 + T Cells Predict Response to Immune Checkpoint Therapy
Published in Frontiers in immunology (12-11-2020)“…Immune checkpoint therapy (ICT) results in durable responses in individuals with some cancers, but not all patients respond to treatment. ICT improves CD8…”
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6
HIV integration sites in latently infected cell lines: evidence of ongoing replication
Published in Retrovirology (13-01-2017)“…Assessing the location and frequency of HIV integration sites in latently infected cells can potentially inform our understanding of how HIV persists during…”
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7
Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART
Published in PLoS pathogens (19-01-2021)“…The precise role of CD4 T cell turnover in maintaining HIV persistence during antiretroviral therapy (ART) has not yet been well characterized. In resting CD4…”
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8
Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis
Published in Nature communications (08-10-2024)“…Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen…”
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9
Uncovering the significance of expanded CD8 + large granular lymphocytes in inclusion body myositis: Insights into T cell phenotype and functional alterations, and disease severity
Published in Frontiers in immunology (30-03-2023)“…Inclusion body myositis (IBM) is a progressive inflammatory myopathy characterised by skeletal muscle infiltration and myofibre invasion by CD8 T lymphocytes…”
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10
Deep sequence analysis of HIV adaptation following vertical transmission reveals the impact of immune pressure on the evolution of HIV
Published in PLoS pathogens (01-12-2019)“…Human immunodeficiency virus (HIV) can adapt to an individual's T cell immune response via genomic mutations that affect antigen recognition and impact disease…”
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11
Prognostic value of HLA-I homozygosity in patients with non-small cell lung cancer treated with single agent immunotherapy
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundWe aimed to assess the impact of genomic human leukocyte antigen (HLA)-I/II homozygosity on the survival benefit of patients with unresectable…”
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12
Transcriptomic Profiling of Influenza A Virus-Infected Mouse Lung at Recovery Stage Using RNA Sequencing
Published in Viruses (31-10-2023)“…Influenza A virus (IAV) is known to cause mild to severe respiratory illness. Under some conditions, the infection can lead to pneumonia (viral or bacterial),…”
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13
New genetic predictors for abacavir tolerance in HLA-B57:01 positive individuals
Published in Human immunology (01-06-2020)“…Abacavir hypersensitivity syndrome (ABC HSS) is strongly associated with carriage of human leukocyte antigen (HLA)-B*57:01, which has a 100% negative…”
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14
Adaptation to HLA-associated immune pressure over the course of HIV infection and in circulating HIV-1 strains
Published in PLoS pathogens (01-12-2022)“…Adaptation to human leukocyte antigen (HLA)-associated immune pressure represents a major driver of human immunodeficiency virus (HIV) evolution at both the…”
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15
Single-cell immunopathology of systemic contact allergy associated with corticosteroids
Published in Journal of dermatological science (01-02-2022)Get full text
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16
Visual Genomics Analysis Studio as a Tool to Analyze Multiomic Data
Published in Frontiers in genetics (17-06-2021)“…Type B adverse drug reactions (ADRs) are iatrogenic immune-mediated syndromes with mechanistic etiologies that remain incompletely understood. Some of the most…”
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17
Infective respiratory syncytial virus is present in human cord blood samples and most prevalent during winter months
Published in PloS one (24-04-2017)“…Human respiratory syncytial virus (RSV) remains the most common cause of severe lower respiratory tract disease amongst infants, and continues to cause annual…”
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18
Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles
Published in Scientific reports (17-08-2017)“…Genes of the human leukocyte antigen (HLA) system encode cell-surface proteins involved in regulation of immune responses, and the way drugs interact with the…”
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19
Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune response
Published in Frontiers in immunology (29-03-2023)“…A vaccine against influenza is available seasonally but is not 100% effective. A predictor of successful seroconversion in adults is an increase in activated…”
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20
Identifying Recombination Hot Spots in the HIV-1 Genome
Published in Journal of Virology (01-03-2014)“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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