Search Results - "CHOI, YOUNG WHAN"
-
1
Nrf2‐mediated neuroprotection against oxygen‐glucose deprivation/reperfusion injury by emodin via AMPK‐dependent inhibition of GSK‐3β
Published in Journal of pharmacy and pharmacology (01-04-2018)“…Objectives Our study verified the neuroprotective properties of emodin against oxygen‐glucose deprivation/reoxygenation (OGD/R) and demonstrated its mechanism…”
Get full text
Journal Article -
2
Cucurbitacin B-, E-, and I-Induced Browning of White Adipocytes Is Promoted by the Inhibition of Phospholipase D2
Published in International journal of molecular sciences (06-12-2022)“…The mechanism of white adipose tissue browning is not well understood; however, naturally occurring compounds are known to play a positive role. The effects of…”
Get full text
Journal Article -
3
OGD/R‐induced ferroptosis and pyroptosis in retinal pigment epithelium cells: Role of PLD1 and PLD2 modulation
Published in Cell biochemistry and function (01-12-2023)“…This study investigated the role of phospholipase D (PLD) in retinal ischemia–reperfusion (I/R) injury using an oxygen‐glucose deprivation/reperfusion (OGD/R)…”
Get full text
Journal Article -
4
Anti-neuroinflammatory Effect of Emodin in LPS-Stimulated Microglia: Involvement of AMPK/Nrf2 Activation
Published in Neurochemical research (01-11-2016)“…AMPK/Nrf2 signaling regulates multiple antioxidative factors and exerts neuroprotective effects. Emodin is one of the main bioactive components extracted from…”
Get full text
Journal Article -
5
Novel Function of α-Cubebenoate Derived from Schisandra chinensis as Lipogenesis Inhibitor, Lipolysis Stimulator and Inflammasome Suppressor
Published in Molecules (Basel, Switzerland) (28-10-2020)“…The efficacy of α-cubebenoate isolated from has been previously studied in three disease areas, namely inflammation, sepsis, and allergy, and its role in other…”
Get full text
Journal Article -
6
Induction of Browning in White Adipocytes: Fucoidan Characterization and Gold Nanoparticle Synthesis from Undaria pinnatifida Sporophyll Extract
Published in Marine drugs (23-11-2023)“…Seaweed extracts and their specific polysaccharides are widely known for their ability to act as reducing and capping agents during nanoparticle synthesis…”
Get full text
Journal Article -
7
Characterization of Plocamium telfairiae Extract-Functionalized Au Nanostructures and Their Anti-Adipogenic Activity through PLD1
Published in Marine drugs (27-06-2022)“…Here, Au nanostructure (AuNS) biosynthesis was mediated through ethanolic extract of Plocamium telfairiae (PT) without the use of stabilizers or surfactants…”
Get full text
Journal Article -
8
Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats
Published in Molecules (Basel, Switzerland) (28-11-2021)“…This study investigated the laxative effects of phlorotannins (Pt) derived from ( ) on chronic constipation by evaluating alterations in stool parameters,…”
Get full text
Journal Article -
9
Adiposity Reduction by Cucumis melo var. gaettongchamoe Extract in High-Fat Diet-Induced Obese Mice
Published in Nutrients (25-07-2023)“…This study investigated the anti-obesity effects of var. (CG) in mice fed a high-fat diet (HFD). The mice received CG water extract (CGWE) treatment for 8…”
Get full text
Journal Article -
10
Citrullus mucosospermus Extract Reduces Weight Gain in Mice Fed a High-Fat Diet
Published in Nutrients (08-07-2024)“…This study aimed to investigate the therapeutic potential of extract (CME) in counteracting adipogenesis and its associated metabolic disturbances in murine…”
Get full text
Journal Article -
11
Edible Vitalmelon Fruit Extract Inhibits Adipogenesis and Ameliorates High-Fat Diet-Induced Obesity
Published in BioMed research international (22-09-2022)“…Conventional breeding of wild (Cucumis melo var. makuwa Makino (CM)) and cultivated (Cucumis melo var. reticulatus (CR)) melons is aimed at improving their…”
Get full text
Journal Article -
12
Petatewalide B alleviates oxygen‑glucose deprivation/reoxygenation‑induced neuronal injury via activation of the AMPK/Nrf2 signaling pathway
Published in Molecular medicine reports (01-07-2020)“…Neuronal injury is a common, and critical, occurrence in clinical ischemic strokes, and can cause irreversible brain damage. However, the precise pathological…”
Get full text
Journal Article -
13
Petasites japonicus bakkenolide B inhibits lipopolysaccharide‑induced pro‑inflammatory cytokines via AMPK/Nrf2 induction in microglia
Published in International journal of molecular medicine (01-03-2018)“…Abnormal neuroinflammatory responses have diverse roles in neuronal death, oxidative stress and neurodegenerative diseases, such as Alzheimer's and Parkinson's…”
Get full text
Journal Article -
14
Treatment with Gold Nanoparticles Using Cudrania tricuspidata Root Extract Induced Downregulation of MMP-2/-9 and PLD1 and Inhibited the Invasiveness of Human U87 Glioblastoma Cells
Published in International journal of molecular sciences (14-02-2020)“…In this study, we aimed to elucidate the anti-invasive effects of root-gold nanoparticles (CTR-GNPs) using glioblastoma cells. We demonstrated the rapid…”
Get full text
Journal Article -
15
AMPK/Nrf2 signaling is involved in the anti-neuroinflammatory action of Petatewalide B from Petasites japonicus against lipopolysaccharides in microglia
Published in Immunopharmacology and immunotoxicology (01-06-2018)“…Abnormal microglia secrete neuroinflammatory factors that play a pivotal role in neurodegenerative-disorder development. Thus, regulating abnormal…”
Get full text
Journal Article -
16
A Comparative Study on Physicochemical, Photocatalytic, and Biological Properties of Silver Nanoparticles Formed Using Extracts of Different Parts of Cudrania tricuspidata
Published in Nanomaterials (Basel, Switzerland) (10-07-2020)“…Green-synthesized silver nanoparticles (SNPs) have great potential for biomedical applications, due to their distinctive optical, chemical, and catalytic…”
Get full text
Journal Article -
17
5-Hydroxymethylfurfural from Black Garlic Extract Prevents TNFα-induced Monocytic Cell Adhesion to HUVECs by Suppression of Vascular Cell Adhesion Molecule-1 Expression, Reactive Oxygen Species Generation and NF-κB Activation
Published in Phytotherapy research (01-07-2011)“…5‐Hydroxymethylfurfural (5‐HMF) is a common Maillard reaction product; the reaction occurs during heat‐processing and the preparation of many types of foods…”
Get full text
Journal Article -
18
Upregulation of heme oxygenase-1 via PI3K/Akt and Nrf-2 signaling pathways mediates the anti-inflammatory activity of Schisandrin in Porphyromonas gingivalis LPS-stimulated macrophages
Published in Immunology letters (30-09-2011)“…Highlights ► In this study, we showed the anti-inflammatory potential of Schisandrin by using P. gingivalis LPS-stimulated RAW 26.7 cells. ► Our results also…”
Get full text
Journal Article -
19
Comparison of anti-inflammatory potential of four different dibenzocyclooctadiene lignans in microglia; action via activation of PKA and Nrf-2 signaling and inhibition of MAPK/STAT/NF-κB pathways
Published in Molecular nutrition & food research (01-04-2014)“…Scope The aim of our study was to determine the signaling pathways associated with the antineuroinflammatory and neuroprotective responses induced by…”
Get full text
Journal Article -
20
Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves
Published in Journal of ethnopharmacology (30-07-2013)“…To elucidate the anti-allergic and anti-inflammatory effects of Petasites genus, we studied the effects of several compounds isolated from Petasites japonicas…”
Get full text
Journal Article