Search Results - "CHOC, M. G"

Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7‐hydroxymethotrexate levels when compared with methotrexate alone by Fox, R. I., Morgan, S. L., Smith, H. T., Robbins, B. A., Choc, M. G., Baggott, J. E.

“…Objective. To study the pharmacokinetics of methotrexate (MTX) plus cyclosporin A (CSA) in patients with rheumatoid arthritis (RA). Methods. On day 1 of the…”
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Bioavailability and pharmacokinetics of cyclosporine formulations: Neoral® vs Sandimmune by Choc, Miles G.

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Pharmacokinetics of an oral solution of the microemulsion formulation of cyclosporine in maintenance pediatric liver transplant recipients by DUNN, S, COONEY, G, SOMMERAUER, J, LINDSAY, C, MCDIARMID, S, WONG, R. L, CHANG, C.-T, SMITH, H. T, CHOC, M. G

“…A comparison of the oral bioavailability of cyclosporine from the original formulation (CsA) and from the new formulation, cyclosporine for microemulsion…”
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Application issues in bioanalytical method validation, sample analysis and data reporting by Dadgar, Darioush, Burnett, Pamela E., Gerry Choc, M., Gallicano, Keith, Hooper, John W.

“…Although some degree of consensus has been reached concerning the requirements for acceptable method validation, the procedures used to establish them vary…”
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Safety and tolerability of cyclosporine microemulsion versus cyclosporine : Two-year data in primary renal allograft recipients : A report of the neoral study group by PESCOVITZ, M. D, BARONE, G, PRUETT, T. L, STINSON, J. B, THOMPSON, J. S, VASQUEZ, E, WAID, T, WOMBOLT, D. G, WONG, R. L, CHOC, M. G, HRICIK, D. E, HWANG, D.-S, JIN, J. H.-J, KLEIN, J. B, MARSH, C. L, MIN, D. I, POLLAK, R

“…The new microemulsion formulation of cyclosporine (CsA-ME) is more bioavailable than cyclosporine (CsA) in de novo renal transplant patients. Therefore, it was…”
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The site and mechanism of dioxygen reduction in bovine heart cytochrome c oxidase by Einarsdóttir, O, Choc, M G, Weldon, S, Caughey, W S

“…The site and mechanism of dioxygen reduction in cytochrome c oxidase from bovine heart muscle have been investigated. The rate of cytochrome c2+ oxidation by…”
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The pharmacokinetics of a microemulsion formulation of cyclosporine in primary renal allograft recipients by BARONE, G, CHANG, C. T, STINSON, J. B, THOMPSON, J. S, VASQUEZ, E, WAID, T, WOMBOLT, D. G, WONG, R. L, CHOC, M. G, KLEIN, J. B, MARSH, C. L, MELIGENI, J. A.A, MIN, D. I, PESCOVITZ, M. D, POLLAK, R, PRUETT, T. L

“…This study was a randomized, double-blind, 12-week comparison of the pharmacokinetics, safety, and tolerability of two cyclosporine (CsA) formulations,…”
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Relative bioavailability of neoral versus sandimmune in the presence of a p450iiia and p-glycoprotein inhibitor by Choc, M.G, Mueller, E.A, Robinson, W.T, Kumle, A, Smith, H.T, Charnick, S.B

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Use of Neoral in pediatric renal transplantation by Ettenger, R E, Smith, H T, Kaiser, B, Cooney, G F, Summerauer, J, Alexander, S, Moulton, L T, Choc, M G, Wong, R L

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Infrared spectra of carbonyl hemoglobins: characterization of dynamic heme pocket conformers by Potter, William T, Hazzard, Jo H, Choc, Miles G, Tucker, Melvin P, Caughey, Winslow S

“…The infrared spectra for carbon monoxide complexed to hemoglobins were examined in the C-O stretch region. Deconvolution of the spectra requires four bands and…”
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The safety and tolerability of cyclosporine emulsion versus cyclosporine in a randomized, double-blind comparison in primary renal allograft recipients by BARONE, G, BUNKE, C. M, PRUETT, T. L, STINSON, J. B, THOMPSON, J. S, VASQUEZ, E, WAID, T, WOMBOLT, D. G, WONG, R. L, CHOC, M. G, HRICIK, D. E, JIN, J. H.-J, KLEIN, J. B, MARSH, C. L, MIN, D. I, PESCOVITZ, M. D, POLLAK, R

“…A 12-week, randomized, double-blind, multicenter pharmacokinetic study was conducted to compare the clinical safety and tolerability of cyclosporine capsules…”
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Multiple-dose pharmacokinetics of clozapine in patients by CHOC, M. G, LEHR, R. G, HSUAN, F, HONIGFELD, G, SMITH, H. T, BORISON, R, VOLAVKA, J

“…After a 2-day buildup, patients were dosed continuously with clozapine solution at three ascending dose levels (37.5, 75, and 150 mg bid for 7 days at each…”
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An infrared study of CO binding to heart cytochrome c oxidase and hemoglobin A. Implications re O2 reactions by Yoshikawa, S, Choc, M G, O'Toole, M C, Caughey, W S

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Properties of a copper-containing cytochrome c1aa3 complex: a terminal oxidase of the extreme thermophile Thermus thermophilus HB8 by Fee, J A, Choc, M G, Findling, K L, Lorence, R, Yoshida, T

“…From the plasma membrane of Thermus thermophilus HB8 we have partially purified a detergent-solubilized complex of cytochromes a and c1 that actively catalyzes…”
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Dynamic Protein Structures: Infrared Evidence for Four Discrete Rapidly Interconverting Conformers at the Carbon Monoxide Binding Site of Bovine Heart Myoglobin by Caughey, Winslow S., Shimada, Hideo, Choc, Miles G., Tucker, Melvin P.

“…Infrared spectra for the carbon monoxide complex with myoglobin isolated as the oxygenyl species from bovine heart muscle were carefully examined in the C--O…”
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Respiratory proteins from the extremely thermophilic aerobic bacterium, Thermus thermophilus. Purification procedures for cytochromes c552, c555,549, and c1aa3 and chemical evidence for a single subunit cytochrome aa3 by Yoshida, T, Lorence, R M, Choc, M G, Tarr, G E, Findling, K L, Fee, J A

“…We have developed a chemically defined, minimal growth medium for Thermus thermophilus which is suitable for nutritional studies, isotopic enrichment, and…”
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Oxygenated intermediate and carbonyl species of cytochrome o (Vitreoscilla): characterization by infrared spectroscopy by CHOC, M. G, WEBSTER, D. A, CAUGHEY, W. S

“…Oxygenated and carbonyl species of cytochrome o (Vitroscilla ) have been studied by infrared spectroscopy to elucidate the nature of FeO sub(2) and FeCO…”
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Improved cyclosporine bioavailability in black pediatric liver transplant recipients after administration of the microemulsion formulation by Cooney, Gerard F., Dunn, Stephen P., Sommerauer, John, Lindsay, Christine, McDiarmid, Sue, Choc, M.Gerry, Smith, Harold T., Chang, Cheng‐Tao, Wong, Robert L.

“…Black transplant recipients are associated with low cyclosporine bioavailability, which may contribute to the poorer clinical outcomes observed with these…”
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Single- vs multiple-dose pharmacokinetics of clozapine in psychiatric patients by CHOC, M. G, HSUAN, F, HONIGFELD, G, ROBINSON, W. T, ERESHEFSKY, L, CRISMON, M. L, SAKLAD, S. R, HIRSCHOWITZ, J, WAGNER, R

“…Clozapine plasma levels were monitored in 16 patients during a series of three consecutive treatments (single dose-multiple dose-single dose). Each patient…”
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High-performance liquid chromatographic method for the determination of fluvastatin in human plasma by Kalafsky, G, Smith, H T, Choc, M G

“…The method outlined in this paper utilizes internal standardization and is simple, reliable, and sensitive for the determination of fluvastatin in plasma…”
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