Search Results - "CHOBANIAN, A. V"

Angiotensin II Induces Fibronectin Expression Associated With Cardiac Fibrosis in the Rat by Crawford, Dennis C, Chobanian, A V, Brecher, Peter

“…Fibronectin expression was studied in the heart of rats given a continuous infusion of angiotensin II (Ang II). Northern blot analysis showed that left…”
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Control of Hypertension — An Important National Priority by Chobanian, Aram V

“…Despite very effective antihypertensive therapies and data from clinical trials demonstrating that lowering blood pressure reduces cardiovascular and renal…”
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Antiatherogenic Effect of Captopril in the Watanabe Heritable Hyperlipidemic Rabbit by Chobanian, Aram V, Haudenschild, Christian C, Nickerson, Cynthia, Drago, Robin

“…The effects of 9 months of orally administered captopril (25–50 nig/kg body wt/day) on aortic atherosclerosis was examined in normotensive Watanabe heritable…”
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1989 corcoran lecture : adaptive and maladaptive responses of the arterial wall to hypertension by CHOBANIAN, A. V

“…This study reviews recent experimental data from our own and other laboratories on the effects of hypertension on the arterial wall and the potential…”
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Growth factor expression in aorta of normotensive and hypertensive rats by SARZANI, R, BRECHER, P, CHOBANIAN, A. V

“…Hypertension causes biochemical and morphological changes in the vessel wall by unknown mechanisms. Locally produced substances may have a role in mediating…”
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Comparison of the effects of AT1 receptor blockade and angiotensin converting enzyme inhibition on atherosclerosis by Hope, Susan, Brecher, Peter, Chobanian, Aram V.

“…Angiotensin converting enzyme (ACE) inhibitors reduce the development of atherosclerosis in hypercholesterolemic animals across a wide range of species…”
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Angiotensin II-induced cardiac fibrosis in the rat is increased by chronic inhibition of nitric oxide synthase by Hou, J, Kato, H, Cohen, R A, Chobanian, A V, Brecher, P

“…These studies were performed to determine if the effects of angiotensin II infusion on the development of cardiac fibrosis could be modified by the chronic…”
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Trandolapril Inhibits Atherosclerosis in the Watanabe Heritable Hyperlipidemic Rabbit by Chobanian, Aram V, Haudenschild, Christian C, Nickerson, Cynthia, Hope, Susan

“…The effects of trandolapril (0.25 mg/kg body wt per 48 hours) on aortic atherosclerosis were examined in the Watanabe heritable hyperlipidemic rabbit treated…”
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Single Risk Factor Intervention May Be Inadequate to Inhibit Atherosclerosis Progression When Hypertension and Hypercholesterolemia Coexist by Chobanian, Aram V

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Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7): Resetting the Hypertension Sails by Lenfant, Claude, Chobanian, Aram V, Jones, Daniel W, Roccella, Edward J

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Salicylate or Aspirin Inhibits the Induction of the Inducible Nitric Oxide Synthase in Rat Cardiac Fibroblasts by Farivar, Saeid R, Chobanian, Aram V, Brecher, Peter

“…To determine if fibroblasts are a source of NO in inflammatory myocardial diseases, we have studied the effect of cytokines on the inducible NO synthase (iNOS)…”
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Effect of hypertension on fibronectin expression in the rat aorta by Takasaki, I, Chobanian, A V, Sarzani, R, Brecher, P

“…Interactions between extracellular fibronectin and vascular cells are thought to influence the phenotype of those cells. To determine if changes in fibronectin…”
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Adventitia as a source of inducible nitric oxide synthase in the rat aorta by Zhang, Hui, Du, Yue, Cohen, Richard A., Chobanian, Aram V., Brecher, Peter

“…In the current study we used in vitro and in vivo models to determine the sites of nitric oxide production in rat aortic tissue following cytokine stimulation…”
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Effect of Nitric Oxide on DNA Replication Induced by Angiotensin II in Rat Cardiac Fibroblasts by Takizawa, Toshikazu, Gu, Miaofen, Chobanian, Aram V, Brecher, Peter

“…Our previous in vivo studies (Hou et al. J Clin Invest. 1995;96:2469-2477.) demonstrated that chronic inhibition of nitric oxide synthase led to an exaggerated…”
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Effects of Angiotensin II Infusion and Inhibition of Nitric Oxide Synthase on the Rat Aorta by Kato, Hiroshi, Hou, Jian, Chobanian, Aram V, Brecher, Peter

“…In previous studies, we showed that in vivo infusion of angiotensin II (Ang II) to adult rats induced vascular changes in gene expression, and this effect did…”
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Hypertension-Induced Changes of Platelet-Derived Growth Factor Receptor Expression in Rat Aorta and Heart by Sarzani, Riccardo, Arnaldi, Giorgio, Chobanian, Aram V

“…Hypertension-associated growth of vascular smooth muscle cells might be mediated in vivo by platelet-derived growth factor (PDGF). Our previous investigations…”
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National Heart, Lung, and Blood Institute Workshop on Sodium and Blood Pressure: A Critical Review of Current Scientific Evidence by Chobanian, Aram V, Hill, Martha

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Influence of Hypertension on Aortic Atherosclerosis in the Watanabe Rabbit by Chobanian, Aram V, Uchtenstein, Alice H, Nilakhe, Vandana, Haudenschild, Christian C, Drago, Robin, Nickerson, Cynthia

“…The effects of one-kidney, one clip Goldblatt hypertension on aortic atherosclerosis have been studied in the Watanabe heritable hyperlipidemic (WHHL) rabbit…”
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Angiotensin II Alters Aortic Fibronectin Independently of Hypertension by Himeno, Hideo, Crawford, Dennis C, Hosoi, Masayuki, Chobanian, Aram V, Brecher, Peter

“…We performed these studies to assess the potential role of hemodynamic forces in mediating the changes in aortic fibronectin mRNA expression that occur in the…”
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 Report by Chobanian, Aram V, Bakris, George L, Black, Henry R, Cushman, William C, Green, Lee A, Izzo, Jr, Joseph L, Jones, Daniel W, Materson, Barry J, Oparil, Suzanne, Wright, Jr, Jackson T, Roccella, Edward J, and the National High Blood Pressure Education Program Coordinating Committee

“…"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure" provides a new guideline for…”
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