Search Results - "CHO, SUNGHEE"

Microglia and Monocyte-Derived Macrophages in Stroke by Kim, Eunhee, Cho, Sunghee

“…Historically, the brain has been considered an immune-privileged organ separated from the peripheral immune system by the blood–brain barrier. However, immune…”
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Genetics of stroke recovery: BDNF val66met polymorphism in stroke recovery and its interaction with aging by Balkaya, Mustafa, Cho, Sunghee

“…Stroke leads to long term sensory, motor and cognitive impairments. Most patients experience some degree of spontaneous recovery which is mostly incomplete and…”
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CD36 as a therapeutic target for endothelial dysfunction in stroke by Cho, Sunghee

“…Stroke pathology involves multifactorial pro-death responses, including inflammation, oxidative stress, vascular dysfunction, and activation of necrotic and…”
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Optimizing functional outcome endpoints for stroke recovery studies by Balkaya, Mustafa, Cho, Sunghee

“…Novel therapeutic intervention that aims to enhance the endogenous recovery potential of the brain during the subacute phase of stroke has produced promising…”
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Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-Val66Met variant by Yang, Jiwon, Park, Keun Woo, Cho, Sunghee

“…Obesity-induced metabolic dysfunctions increase the risk for vascular diseases, including type II diabetes and stroke. Managing obesity is of interest to…”
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Cell Surface CD36 Protein in Monocyte/Macrophage Contributes to Phagocytosis during the Resolution Phase of Ischemic Stroke in Mice by Woo, Moon-Sook, Yang, Jiwon, Beltran, Cesar, Cho, Sunghee

“…Infiltrating monocyte-derived macrophages (M-MΦ) influence stroke-induced brain injury. Although the inflammatory nature of M-MΦ in acute stroke has been well…”
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Role of Spleen-Derived Monocytes/Macrophages in Acute Ischemic Brain Injury by Kim, Eunhee, Yang, Jiwon, Beltran, Cesar D, Cho, Sunghee

“…Monocytes/macrophages (MMs), mononuclear phagocytes, have been implicated in stroke-induced inflammation and injury. However, the presence of pro-inflammatory…”
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Corticosterone-Mediated Body Weight Loss Is an Important Catabolic Process for Poststroke Immunity and Survival by Yang, Jiwon, Kim, Eunhee, Beltran, Cesar, Cho, Sunghee

“…BACKGROUND AND PURPOSE—Stroke-induced acute severe body weight (BW) loss is associated with a high rate of mortality during a critical poststroke period…”
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Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia by Ju, Hyunwoo, Park, Keun Woo, Kim, Il-Doo, Cave, John W, Cho, Sunghee

“…Monocyte-derived macrophages (MDMs) and microglia elicit neural inflammation and clear debris for subsequent tissue repair and remodeling. The role of…”
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Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury by Vivinetto, Ana L., Kim, Il-doo, Goldberg, David C., Fones, Lilah, Brown, Elizabeth, Tarabykin, Victor S., Hill, Caitlin E., Cho, Sunghee, Cave, John W.

“…The astrocytic response to injury is characterized on the cellular level, but our understanding of the molecular mechanisms controlling the cellular processes…”
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A role for spleen monocytes in post-ischemic brain inflammation and injury by Bao, Yi, Kim, Eunhee, Bhosle, Sangram, Mehta, Heeral, Cho, Sunghee

“…Although infiltration of peripheral monocytes/macrophages is implicated in stroke pathology, in vivo data regarding the deployment of monocytes and their…”
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Prohibitin reduces mitochondrial free radical production and protects brain cells from different injury modalities by Zhou, Ping, Qian, Liping, D'Aurelio, Marilena, Cho, Sunghee, Wang, Gang, Manfredi, Giovanni, Pickel, Virginia, Iadecola, Costantino

“…Prohibitin is an essential mitochondrial protein that has been implicated in a wide variety of functions in many cell types, but its role in neurons remains…”
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CD36 is Involved in Astrocyte Activation and Astroglial Scar Formation by Bao, Yi, Qin, Luye, Kim, Eunhee, Bhosle, Sangram, Guo, Hengchang, Febbraio, Maria, Haskew-Layton, Renee E, Ratan, Rajiv, Cho, Sunghee

“…Inflammation is an essential component for glial scar formation. However, the upstream mediator(s) that triggers the process has not been identified…”
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Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity by Kawano, Takayuki, Anrather, Josef, Zhou, Ping, Park, Laibaik, Wang, Gang, Frys, Kelly A, Kunz, Alexander, Cho, Sunghee, Orio, Marcello, Iadecola, Costantino

“…Cyclooxygenase-2 (COX-2), a rate-limiting enzyme for prostanoid synthesis, has been implicated in the neurotoxicity resulting from hypoxia-ischemia, and its…”
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Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β by Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino, Südhof, Thomas C.

“…Increasing evidence indicates that cerebrovascular dysfunction plays a pathogenic role in Alzheimer's dementia (AD). Amyloid-β (Aβ), a peptide central to the…”
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A Novel Cell-permeable Antioxidant Peptide, SS31, Attenuates Ischemic Brain Injury by Down-regulating CD36 by Cho, Sunghee, Szeto, Hazel H., Kim, Eunhee, Kim, Hyunjoo, Tolhurst, Aaron T., Pinto, John T.

“…Oxidative stress is implicated in the pathogenesis of ischemia/reperfusion injury. Recently, we demonstrated that activation of CD36, a class B scavenger…”
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CD36: A multi-modal target for acute stroke therapy by Cho, Sunghee, Kim, Eunhee

“…A role for CD36 in the pathogenesis of atherosclerosis, inflammation and lipid metabolism has been well-documented. However, little is known about the role of…”
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Recent advances in two-photon imaging： technology developments and biomedical applications by Yu Chen, Yu Chen, Hengchang Guo, Hengchang Guo, Wei Gong, Wei Gong, Luye Qin, Luye Qin, Hossein Aleyasin, Hossein Aleyasin, Rajiv R Ratan, Rajiv R Ratan, Sunghee Cho, Sunghee Cho, Jianxin Chen, Jianxin Chen, Shusen Xie, Shusen Xie

“…In the past two decades, two-photon microscopy （TPM） transforms biomedicalresearch, allowing non- destructive high-resolution fluorescent molecular imaging and…”
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CD36 in the periphery and brain synergizes in stroke injury in hyperlipidemia by Kim, Eunhee, Febbraio, Maria, Bao, Yi, Tolhurst, Aaron T., Epstein, Jeffrey M., Cho, Sunghee

“…Objective: Hyperlipidemia exacerbates ischemic stroke outcome and increases CD36 expression in the postischemic brain as well as in peripheral…”
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Association of Substantia Nigra Degeneration with Poor Neurological Recovery in Basal Ganglia Infarctions by Lee, Kijeong, Lee, HyungWoo, Kim, Young Dae, Nam, Hyo Suk, Lee, Hye Sun, Yoo, Joonsang, Cho, Sunghee, Heo, Ji Hoe

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