Search Results - "CHO, Hanna"
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Climate Change Risk Assessment for Kurunegala, Sri Lanka: Water and Heat Waves
Published in Climate (Basel) (01-12-2020)“…Sri Lanka is experiencing various social and environmental challenges, including drought, storms, floods, and landslides, due to climate change. One of Sri…”
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In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum
Published in Annals of neurology (01-08-2016)“…Objective To determine the in vivo cortical spreading pattern of tau and amyloid and to establish positron emission tomography (PET) image‐based tau staging in…”
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Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders
Published in JAMA : the journal of the American Medical Association (18-09-2018)“…IMPORTANCE: The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core…”
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4
Collagen piezoelectricity in osteogenesis imperfecta and its role in intrafibrillar mineralization
Published in Communications biology (11-11-2022)“…Intrafibrillar mineralization plays a critical role in attaining desired mechanical properties of bone. It is well known that amorphous calcium phosphate (ACP)…”
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Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer's disease
Published in Alzheimer's research & therapy (31-10-2020)“…To assess the effects of apolipoprotein E (ApoE) ε4 genotype on amyloid-β (Aβ) and tau burden and their longitudinal changes in Alzheimer's disease (AD)…”
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Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway
Published in Science (American Association for the Advancement of Science) (13-03-2015)“…Rgs2, a regulator of G proteins, lowers blood pressure by decreasing signaling through Gαq. Human patients expressing Met-Leu-Rgs2 (ML-Rgs2) or Met-Arg-Rgs2…”
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Anatomical heterogeneity of Alzheimer disease: Based on cortical thickness on MRIs
Published in Neurology (18-11-2014)“…OBJECTIVE:Because the signs associated with dementia due to Alzheimer disease (AD) can be heterogeneous, the goal of this study was to use 3-dimensional MRI to…”
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Distinct patterns of amyloid‐dependent tau accumulation in Lewy body diseases
Published in Movement disorders (01-02-2018)“…ABSTRACT Background: In addition to Lewy body pathology, amyloid‐β plaques and neurofibrillary tangles that are characteristic for Alzheimer's disease are also…”
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Antitumor Effects and Mechanisms of AZD4547 on FGFR2-Deregulated Endometrial Cancer Cells
Published in Molecular cancer therapeutics (01-10-2015)“…Uncontrolled activation of FGFRs induces the progression of various cancers. It was recently reported that FGFR2-activating mutants are implicated in about 12%…”
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The N-Terminal Methionine of Cellular Proteins as a Degradation Signal
Published in Cell (16-01-2014)“…The Arg/N-end rule pathway targets for degradation proteins that bear specific unacetylated N-terminal residues while the Ac/N-end rule pathway targets…”
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Assessment of Extent and Role of Tau in Subcortical Vascular Cognitive Impairment Using 18F-AV1451 Positron Emission Tomography Imaging
Published in JAMA neurology (01-08-2018)“…Amyloid-β (Aβ), tau, and cerebral small vessel disease (CSVD), which occasionally coexist, are the most common causes of cognitive impairments in older people…”
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Strong internal resonance in a nonlinear, asymmetric microbeam resonator
Published in Microsystems & nanoengineering (26-01-2021)“…Exploiting nonlinear characteristics in micro/nanosystems has been a subject of increasing interest in the last decade. Among others, vigorous intermodal…”
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Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs
Published in Frontiers in oncology (01-11-2021)“…Inhibitors of tropomyosin-related kinases (TRKs) display remarkable outcomes in the regression of cancers harboring the Neurotrophin Receptors Tyrosine Kinase…”
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Associations between non-alcoholic fatty liver disease and cognitive impairment and the effect modification of inflammation
Published in Scientific reports (23-07-2022)“…This study aimed to evaluate the association between non-alcoholic fatty liver disease (NAFLD) and cognitive impairment and explore the effect modification by…”
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Amplified fluorogenic immunoassay for early diagnosis and monitoring of Alzheimer’s disease from tear fluid
Published in Nature communications (09-12-2023)“…Accurate diagnosis of Alzheimer’s disease (AD) in its earliest stage can prevent the disease and delay the symptoms. Therefore, more sensitive, non-invasive,…”
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Risk of Incident Dementia According to Metabolic Health and Obesity Status in Late Life: A Population-Based Cohort Study
Published in The journal of clinical endocrinology and metabolism (01-07-2019)“…Abstract Context The risk for dementia among subjects who are obese with normal metabolic profiles, or called metabolically healthy obese (MHO), remains…”
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Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity
Published in Proceedings of the National Academy of Sciences - PNAS (26-02-2008)“…$BRAF^{V600E}$ is the most frequent oncogenic protein kinase mutation known. Furthermore, inhibitors targeting "active" protein kinases have demonstrated…”
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Bickerstaff’s brainstem encephalitis: a rare case of neurologic complication in Ulcerative Colitis
Published in BMC neurology (26-10-2023)“…Bickerstaff’s brainstem encephalitis is a rare autoimmune disorder that presents with ataxia, ophthalmoplegia, disturbance of consciousness and quadriplegia. A…”
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Association between physical activity and conversion from mild cognitive impairment to dementia
Published in Alzheimer's research & therapy (11-11-2020)“…Physical activity has been suggested to prevent the conversion of mild cognitive impairment (MCI) to dementia in patients. We investigated the association…”
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Head to head comparison of [18F] AV-1451 and [18F] THK5351 for tau imaging in Alzheimer’s disease and frontotemporal dementia
Published in European journal of nuclear medicine and molecular imaging (01-03-2018)“…Purpose Tau accumulation is a core pathologic change in various neurodegenerative diseases including Alzheimer’s disease and frontotemporal lobar…”
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