Search Results - "CHINTAPALLI, Sree V"
-
1
Enhanced offspring predisposition to steatohepatitis with maternal high-fat diet is associated with epigenetic and microbiome alterations
Published in PloS one (17-04-2017)“…Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated with obesity and a precursor to steatohepatitis. However, the contributions…”
Get full text
Journal Article -
2
Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice
Published in Scientific reports (07-11-2018)“…The contributions of maternal diet and obesity in shaping offspring microbiome remain unclear. Here we employed a mouse model of maternal diet-induced obesity…”
Get full text
Journal Article -
3
Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
Published in International journal of molecular sciences (26-04-2022)“…Myoglobin (Mb)-mediated oxygen (O ) delivery and dissolved O in the cytosol are two major sources that support oxidative phosphorylation. During intense…”
Get full text
Journal Article -
4
Myoglobin–Pyruvate Interactions: Binding Thermodynamics, Structure–Function Relationships, and Impact on Oxygen Release Kinetics
Published in International journal of molecular sciences (01-08-2022)“…Myoglobin (Mb), besides its roles as an oxygen (O2) carrier/storage protein and nitric oxide NO scavenger/producer, may participate in lipid trafficking and…”
Get full text
Journal Article -
5
Associations between Maternal Diet, Body Composition and Gut Microbial Ecology in Pregnancy
Published in Nutrients (21-09-2021)“…Maternal body composition, gestational weight gain (GWG) and diet quality influence offspring obesity risk. While the gut microbiome is thought to play a…”
Get full text
Journal Article -
6
Formula diet driven microbiota shifts tryptophan metabolism from serotonin to tryptamine in neonatal porcine colon
Published in Microbiome (14-07-2017)“…The gut microbiota of breast-fed and formula-fed infants differ significantly, as do the risks for allergies, gut dysfunction, and upper respiratory tract…”
Get full text
Journal Article -
7
Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2020)“…Trehalose is a disaccharide that might be used in the treatment of cardiometabolic diseases. However, trehalose consumption promotes the expansion of…”
Get full text
Journal Article -
8
Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy
Published in International journal of molecular sciences (26-11-2022)“…Previous research has indicated that various metabolites belonging to phenolic acids (PAs), produced by gut microflora through the breakdown of polyphenols,…”
Get full text
Journal Article -
9
Gut Microbiome and Metabolome Modulation by Maternal High-Fat Diet and Thermogenic Challenge
Published in International journal of molecular sciences (25-08-2022)“…The gut microbiota plays a critical role in energy homeostasis and its dysbiosis is associated with obesity. Maternal high-fat diet (HFD) and β-adrenergic…”
Get full text
Journal Article -
10
Sex-Specific Changes in Gut Microbiome Composition following Blueberry Consumption in C57BL/6J Mice
Published in Nutrients (01-02-2019)“…The antioxidant and anti-inflammatory properties of blueberries improve vascular function and insulin sensitivity. However, the bioavailability of the active…”
Get full text
Journal Article -
11
Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice
Published in Frontiers in endocrinology (Lausanne) (04-10-2024)“…Maternal undernutrition is the most common cause of fetal growth restriction (FGR) worldwide. FGR increases morbidity and mortality during infancy, as well as…”
Get full text
Journal Article -
12
The BRCA1 Tumor Suppressor Binds to Inositol 1,4,5-Trisphosphate Receptors to Stimulate Apoptotic Calcium Release
Published in The Journal of biological chemistry (13-03-2015)“…The inositol 1,4,5-trisphosphate receptor (IP3R) is a ubiquitously expressed endoplasmic reticulum (ER)-resident calcium channel. Calcium release mediated by…”
Get full text
Journal Article -
13
Computational Analysis Reveals Unique Binding Patterns of Oxygenated and Deoxygenated Myoglobin to the Outer Mitochondrial Membrane
Published in Biomolecules (Basel, Switzerland) (01-07-2023)“…Myoglobin (Mb) interaction with the outer mitochondrial membrane (OMM) promotes oxygen (O ) release. However, comprehensive molecular details on specific…”
Get full text
Journal Article -
14
Molecular dynamic simulations reveal the structural determinants of Fatty Acid binding to oxy-myoglobin
Published in PloS one (01-06-2015)“…The mechanism(s) by which fatty acids are sequestered and transported in muscle have not been fully elucidated. A potential key player in this process is the…”
Get full text
Journal Article -
15
Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor
Published in Bioinformatics and biology insights (01-11-2021)“…The transmembrane G-protein coupled receptor GPR109A has been previously shown to function as a receptor for niacin in mediating antilipolytic effects…”
Get full text
Journal Article -
16
Unraveling Protein-Metabolite Interactions in Precision Nutrition: A Case Study of Blueberry-Derived Metabolites Using Advanced Computational Methods
Published in Metabolites (03-08-2024)“…Metabolomics, the study of small-molecule metabolites within biological systems, has become a potent instrument for understanding cellular processes. Despite…”
Get full text
Journal Article -
17
Sex differences in skeletal muscle revealed through fiber type, capillarity, and transcriptomics profiling in mice
Published in Physiological reports (01-09-2021)“…Skeletal muscle anatomy and physiology are sexually dimorphic but molecular underpinnings and muscle‐specificity are not well‐established. Variances in…”
Get full text
Journal Article -
18
C‐section increases cecal abundance of the archetypal bile acid and glucocorticoid modifying Lachnoclostridium [clostridium] scindens in mice
Published in Physiological reports (01-07-2022)“…In humans and animal models, Cesarean section (C‐section) has been associated with alterations in the taxonomic structure of the gut microbiome. These changes…”
Get full text
Journal Article -
19
GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice
Published in Communications biology (08-01-2021)“…The G protein-coupled receptor 109 A (GPR109A) is robustly expressed in osteoclastic precursor macrophages. Previous studies suggested that GPR109A mediates…”
Get full text
Journal Article -
20
Conserved GXXXG- and S/T-Like Motifs in the Transmembrane Domains of NS4B Protein Are Required for Hepatitis C Virus Replication
Published in Journal of Virology (01-07-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article