Search Results - "CHILLON, M. Carmen"

Liquid biopsy: a non‐invasive approach for Hodgkin lymphoma genotyping by Alcoceba, Miguel, García‐Álvarez, María, Chillón, M. Carmen, Jiménez, Cristina, Medina, Alejandro, Antón, Alicia, Blanco, Oscar, Díaz, Luis G., Tamayo, Pilar, González‐Calle, Verónica, Vidal, María Jesús, Cuello, Rebeca, Díaz Gálvez, Francisco Javier, Queizán, José Antonio, Martín, Alejandro, González, Marcos, García‐Sanz, Ramón, Sarasquete, M. Eugenia

“…Summary The Hodgkin lymphoma (HL) genomic landscape is hardly known due to the scarcity of tumour cells in the tissue. Liquid biopsy employing circulating…”
Get full text

Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease by Alcoceba, Miguel, Stewart, James P, García-Álvarez, María, Díaz, Luis G, Jiménez, Cristina, Medina, Alejandro, Chillón, M Carmen, Gazdova, Jana, Blanco, Oscar, Díaz, Francisco J, Peñarrubia, María J, Fernández, Silvia, Montes, Carlos, Cabero, Almudena, Caballero, María D, García-Sanz, Ramón, González, Marcos, González, David, Tamayo, Pilar, Gutiérrez, Norma C, García-Sancho, Alejandro Martín, Sarasquete, M Eugenia

“…Circulating tumour DNA (ctDNA) allows genotyping and minimal residual disease (MRD) detection in lymphomas. Using a next-generation sequencing (NGS) approach…”
Get full text

Molecular Characterization of Immunoglobulin Gene Rearrangements in Diffuse Large B-Cell Lymphoma: Antigen-Driven Origin and IGHV4-34 as a Particular Subgroup of the Non-GCB Subtype by SEBASTIAN, Elena, ALCOCEBA, Miguel, CORRAL, Rocío, PARDAL, Emilia, MARTIN, Alejandro, GONZALEZ-BARCA, Eva, DOLORES CABALLERO, M, SAN MIGUEL, Jesus F, GARCIA-SANZ, Ramón, GONZALEZ, Marcos, BALANZATEGUI, Ana, MARIN, Luis, MONTES-MORENO, Santiago, FLORES, Teresa, GONZALEZ, David, EUGENIA SARASQUETE, M, CARMEN CHILLON, M, PUIG, Noemí

“…The pathogenesis of diffuse large B-cell lymphoma (DLBCL) remains partially unknown. The analysis of the B-cell receptor of the malignant cells could…”
Get full text

A New Next-Generation Sequencing Strategy for the Simultaneous Analysis of Mutations and Chromosomal Rearrangements at DNA Level in Acute Myeloid Leukemia Patients by Prieto-Conde, M. Isabel, Corchete, Luis A., García-Álvarez, María, Jiménez, Cristina, Medina, Alejandro, Balanzategui, Ana, Hernández-Ruano, Montserrat, Maldonado, Rebeca, Sarasquete, M. Eugenia, Alcoceba, Miguel, Puig, Noemí, González-Calle, Verónica, García-Sanz, Ramón, Gutiérrez, Norma C., González-Díaz, Marcos, Chillón, M. Carmen

“…Acute myeloid leukemias (AMLs) are currently genomically characterized by karyotype, fluorescence in situ hybridization (FISH), real-time quantitative PCR, and…”
Get full text

HLA specificities are associated with prognosis in IGHV-mutated CLL-like high-count monoclonal B cell lymphocytosis by García-Álvarez, María, Alcoceba, Miguel, López-Parra, Miriam, Puig, Noemí, Antón, Alicia, Balanzategui, Ana, Prieto-Conde, Isabel, Jiménez, Cristina, Sarasquete, María E, Chillón, M Carmen, Gutiérrez, María Laura, Corral, Rocío, Alonso, José María, Queizán, José Antonio, Vidán, Julia, Pardal, Emilia, Peñarrubia, María Jesús, Bastida, José M, García-Sanz, Ramón, Marín, Luis, González, Marcos

“…Molecular alterations leading progression of asymptomatic CLL-like high-count monoclonal B lymphocytosis (hiMBL) to chronic lymphocytic leukemia (CLL) remain…”
Get full text

HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma by Alcoceba, Miguel, Sebastián, Elena, Marín, Luis, Balanzategui, Ana, Sarasquete, M. Eugenia, Chillón, M. Carmen, Jiménez, Cristina, Puig, Noemí, Corral, Rocío, Pardal, Emilia, Grande, Carlos, Bello, José Luis, Albo, Carmen, de la Cruz, Fátima, Panizo, Carlos, Martín, Alejandro, González-Barca, Eva, Caballero, M. Dolores, San Miguel, Jesús F., García-Sanz, Ramón, González, Marcos

“…Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease influenced by genetic and environmental factors. The role of the HLA system in tumor antigen…”
Get full text

Wilms Tumor 1 gene expression levels improve risk stratification in AML patients. Results of a multicentre study within the Spanish Group for Molecular Biology in Haematology by Martínez‐Laperche, Carolina, Kwon, Mi, Franco‐Villegas, Ana C., Chillón, M. Carmen, Castro, Nerea, Anguita, Eduardo, Dolz, Sandra, Rodríguez‐Medina, Carlos, Hermosín, Lourdes, Bellón, José M., Prieto‐Conde, Mª Isabel, Barragán, Eva, Gómez‐Casares, Maite, Ayala, Rosa, Martínez‐López, Joaquín, González‐Díaz, Marcos, Díez‐Martin, José Luis, Buño, Ismael

Get full text

Focal Adhesion Genes Refine the Intermediate-Risk Cytogenetic Classification of Acute Myeloid Leukemia by Pallarès, Victor, Hoyos, Montserrat, Chillón, M Carmen, Barragán, Eva, Prieto Conde, M Isabel, Llop, Marta, Falgàs, Aïda, Céspedes, María Virtudes, Montesinos, Pau, Nomdedeu, Josep F, Brunet, Salut, Sanz, Miguel Ángel, González-Díaz, Marcos, Sierra, Jorge, Mangues, Ramon, Casanova, Isolda

“…In recent years, several attempts have been made to identify novel prognostic markers in patients with intermediate-risk acute myeloid leukemia (IR-AML), to…”
Get full text

Immunoglobulin gene rearrangement IGHV3-48 is a predictive marker of histological transformation into aggressive lymphoma in follicular lymphomas by García-Álvarez, María, Alonso-Álvarez, Sara, Prieto-Conde, Isabel, Jiménez, Cristina, Sarasquete, M. Eugenia, Chillón, M. Carmen, Medina, Alejandro, Balanzategui, Ana, Maldonado, Rebeca, Antón, Alicia, Puig, Noemí, Rodríguez, Marta, Blanco, Oscar, Tamayo, Pilar, González-Calle, Verónica, Martín, Alejandro, García-Sanz, Ramón, González, Marcos, Caballero, M. Dolores, Alcoceba, Miguel

“…Follicular lymphoma (FL) is a heterogeneous disease whose pathogenesis remains partially unknown. Around 20% of FL patients experience early progression or…”
Get full text

Genetic complexity impacts the clinical outcome of follicular lymphoma patients by García-Álvarez, María, Alonso-Álvarez, Sara, Prieto-Conde, Isabel, Jiménez, Cristina, Sarasquete, M. Eugenia, Chillón, M. Carmen, Medina, Alejandro, Balanzategui, Ana, Maldonado, Rebeca, Antón, Alicia, Rodríguez, Marta, Blanco, Oscar, Díaz, Luis G., Tamayo, Pilar, Blanco, Pedro, Esteban, Carmen, González-Calle, Verónica, Puig, Noemí, Gutiérrez, Norma, Martín, Alejandro, García-Sanz, Ramón, González, Marcos, Caballero, M. Dolores, Alcoceba, Miguel

Get full text

Do endothelial cells belong to the primitive stem leukemic clone in CML? Role of extracellular vesicles by Ramos, Teresa L, Sánchez-Abarca, Luis Ignacio, López-Ruano, Guillermo, Muntión, Sandra, Preciado, Silvia, Hernández-Ruano, Montserrat, Rosado, Belén, de las Heras, Natalia, Chillón, M. Carmen, Hernández-Hernández, Ángel, González, Marcos, Sánchez-Guijo, Fermín, del Cañizo, Consuelo

“…Abstract The expression of BCR-ABL in hematopoietic stem cells is a well-defined primary event in chronic myeloid leukemia (CML). Some reports have described…”
Get full text

Clinical and Prognostic Value of Discrepancies in Microsatellite DNA Regions Between Recipient and Donor in Human Leukocyte Antigen-Identical Allogeneic Transplantation Setting by ALCOCEBA, Miguel, BALANZATEGUI, Ana, SAN MIGUEL, Jesus F, GARCIA-SANZ, Ramon, GONZALEZ, Marcos, DIEZ-CAMPELO, Maria, MARTIN-JIMENEZ, Patricia, SARASQUETE, Maria Eugenia, CHILLON, M. Carmen, SANTAMARIA, Carlos, PEREZ-SIMON, Jose Antonio, MARIN, Luis, CABALLERO, M. Dolores

“…Detection of recipient versus donor disparities in microsatellite DNA regions (short tandem repeats [STR]) allows for sensitive and specific monitorization of…”
Get full text

Molecular characteristics and gene segment usage in IGH gene rearrangements in multiple myeloma by Gonzalez, D, Gonzalez, M, Balanzategui, A, Sarasquete, ME, Lopez-Perez, R, Chillon, MC, Garcia-Sanz, R, San Miguel, JF

“…Hematology Service, University Hospital of Salamanca and Center for Cancer Research, University of Salamanca, Spain. BACKGROUND AND OBJECTIVES: Analysis of IgH…”
Get full text

Molecular profiling of immunoglobulin heavy-chain gene rearrangements unveils new potential prognostic markers for multiple myeloma patients by Medina, Alejandro, Jiménez, Cristina, Sarasquete, M. Eugenia, González, Marcos, Chillón, M. Carmen, Balanzategui, Ana, Prieto-Conde, Isabel, García-Álvarez, María, Puig, Noemí, González-Calle, Verónica, Alcoceba, Miguel, Cuenca, Isabel, Barrio, Santiago, Escalante, Fernando, Gutiérrez, Norma C., Gironella, Mercedes, Hernández, Miguel T., Sureda, Anna, Oriol, Albert, Bladé, Joan, Lahuerta, Juan-José, San Miguel, Jesús F., Mateos, María-Victoria, Martínez-López, Joaquín, Calasanz, María-José, García-Sanz, Ramón

“…Multiple myeloma is a heterogeneous disease whose pathogenesis has not been completely elucidated. Although B-cell receptors play a crucial role in myeloma…”
Get full text

NEDD9 , an independent good prognostic factor in intermediate-risk acute myeloid leukemia patients by Pallarès, Victor, Hoyos, Montserrat, Chillón, M Carmen, Barragán, Eva, Conde, M Isabel Prieto, Llop, Marta, Céspedes, María Virtudes, Nomdedeu, Josep F, Brunet, Salut, Sanz, Miguel Ángel, González-Díaz, Marcos, Sierra, Jorge, Casanova, Isolda, Mangues, Ramon

“…Intermediate-risk acute myeloid leukemia (IR-AML) is the largest subgroup of AML patients and is highly heterogeneous. Whereas adverse and favourable risk…”
Get full text

Preferential Acquision of N-Glycosylation Sites in the VDJ Region in Germinal Center B-Cell-Like Difusse Large B-Cell Lymphoma by Alcoceba, Miguel, Sebastián, Elena, Balanzategui, Ana, Marín, Luis, Montes-Moreno, Santiago, Flores, Teresa, Puig, Noemí, Sarasquete, M. Eugenia, Chillón, M. Carmen, Jiménez, Cristina, Corral, Rocío, González-Barca, Eva, Caballero, M. Dolores, Miguel, Jesús F. San, García-Sanz, Ramón, González, Marcos

“…Abstract 1589 Acquired potentially N-glycosylation sites are produced by somatic hypermutation (SHM) in the immunoglobulin (Ig) variable region. This…”
Get full text

Relationship Between HLA Class I and II Polymorphisms with Susceptibility and Clinical Outcome in Diffuse Large B-Cell Lymphoma by Alcoceba, Miguel, Sebastián, Elena, Marín, Luis, Balanzategui, Ana, Caballero, M. Dolores, González-Barca, Eva, Pardal, Emilia, Martin, Alejandro, Grande, Carlos, Bello, José Luis, Albo, Carmen, de la Cruz, Fatima, Panizo, Carlos, Conde, Eulogio, Sarasquete, M. Eugenia, Chillón, M. Carmen, Jiménez, Cristina, Puig, Noemí, Corral, Rocío, Miguel, Jesús F. San, García-Sanz, Ramón, González, Marcos

“…Abstract 2680 The Human Leukocyte Antigen (HLA) system plays an important role in antitumor immune response. In the last years, different genome-wide…”
Get full text

Molecular Characterization of Immunoglobulin Gene Rearrangements in Diffuse Large B-Cell Lymphoma by Sebastián, Elena, Alcoceba, Miguel, Balanzategui, Ana, Marín, Luis, Montes-Moreno, Santiago, Flores, Teresa, González, David, Sarasquete, M. Eugenia, Chillón, M. Carmen, Puig, Noemí, Corral, Rocío, Pardal, Emilia, Martín, Alejandro, González-Barca, Eva, Caballero, M. Dolores, San Miguel, Jesús F, García-Sanz, Ramón, González, Marcos

“…The pathogenesis of diffuse large B-cell lymphoma (DLBCL) remains partially unknown. The analysis of the B-cell receptor of the malignant cells could…”
Get full text

Whole-Exome Sequencing of Waldenström Macroglobulinemia Transformation into Aggressive Lymphoma by Alonso, Sara, Jiménez, Cristina, Alcoceba, Miguel, García-Álvarez, María, Prieto-Conde, Isabel, Chillon, M. Carmen, Sarasquete, M. Eugenia A., Puig, Noemi, Mateos, Maria-Victoria, Ocio, Enrique M., González, Marcos, Garcia-Sanz, Ramon

“…INTRODUCTION Waldenström Macroglobulinemia (WM) has an indolent clinical course. However, as in other indolent lymphoproliferative disorders, transformation…”
Get full text

FLT3-activating mutations are associated with poor prognostic features in AML at diagnosis but they are not an independent prognostic factor by Chillón, M Carmen, Fernández, Carina, García-Sanz, Ramón, Balanzategui, Ana, Ramos, Fernando, Fernández-Calvo, Javier, González, Marcos, Miguel, Jesús F San

“…FLT3: gene alterations (internal tandem duplications - ITDs - and D835 mutations) are thought to be associated with poor-risk acute myeloid leukemia (AML)…”
Get more information