Search Results - "CHILES, C"

Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation by Strelko, Cheryl L, Lu, Wenyun, Dufort, Fay J, Seyfried, Thomas N, Chiles, Thomas C, Rabinowitz, Joshua D, Roberts, Mary F

“…Itaconic acid (ITA), or methylenesuccinic acid, is not generally classified as a mammalian metabolite. Using NMR-based metabolomics and 13C-labeling, we have…”
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The Burden of Cardiovascular Disease from Air Pollution in Rwanda by Taghian, Gabriella, Fisher, Samantha, Chiles, Thomas C, Binagwaho, Agnes, Landrigan, Philip J

“…Rwanda, like many countries in sub-Saharan Africa, is still relatively early in development. Industrialization and urbanization are major drivers of the…”
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Protein kinase Cβ is critical for the metabolic switch to glycolysis following B-cell antigen receptor engagement by Blair, Derek, Dufort, Fay J, Chiles, Thomas C

“…Signals derived from the BCR (B-cell antigen receptor) control survival, development and antigenic responses. One mechanism by which BCR signals may mediate…”
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Association between Reperfusion Renal Allograft Biopsy Findings and Transplant Outcomes by Mohan, Sumit, Campenot, Eric, Chiles, Mariana C, Santoriello, Dominick, Bland, Eric, Crew, R John, Rosenstiel, Paul, Dube, Geoffrey, Batal, Ibrahim, Radhakrishnan, Jai, Sandoval, P Rodrigo, Guarrera, James, Stokes, M Barry, D'Agati, Vivette, Cohen, David J, Ratner, Lloyd E, Markowitz, Glen

“…Biopsy findings at the time of procurement of deceased donor kidneys remain the most common reason cited for kidney discard. To determine the value of renal…”
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Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth by Doughty, Cheryl A., Bleiman, Blair F., Wagner, Dean J., Dufort, Fay J., Mataraza, Jennifer M., Roberts, Mary F., Chiles, Thomas C.

“…The bioenergetic response of B lymphocytes is subject to rapid changes following antigen encounter in order to provide ATP and anabolic precursors necessary to…”
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Cigarette smoking and 9/11-related posttraumatic stress disorder among World Trade Center Health Registry enrollees, 2003–12 by Welch, Alice E, Jasek, John P, Caramanica, Kimberly, Chiles, Mariana C, Johns, Michael

“…Abstract Objective Numerous studies have observed higher rates of smoking among adults with mental health conditions. We examined posttraumatic stress disorder…”
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Cutting Edge: IL-4-Mediated Protection of Primary B Lymphocytes from Apoptosis via Stat6-Dependent Regulation of Glycolytic Metabolism by Dufort, Fay J, Bleiman, Blair F, Gumina, Maria R, Blair, Derek, Wagner, Dean J, Roberts, Mary F, Abu-Amer, Yousef, Chiles, Thomas C

“…IL-4 prevents the death of naive B lymphocytes through the up-regulation of antiapoptotic proteins such as Bcl-x(L). Despite studies implicating glucose…”
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Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing by Cai, Dong, Mataraza, Jennifer M, Qin, Zheng-Hong, Huang, Zhongping, Huang, Jianyu, Chiles, Thomas C, Carnahan, David, Kempa, Kris, Ren, Zhifeng

“…Introduction of exogenous DNA into mammalian cells represents a powerful approach for manipulating signal transduction. The available techniques, however, are…”
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The Minderoo-Monaco Commission on Plastics and Human Health by Landrigan, Philip J, Raps, Hervé, Cropper, Maureen, Bald, Caroline, Brunner, Manuel, Canonizado, Elvia Maya, Charles, Dominic, Chiles, Thomas C, Donohue, Mary J, Enck, Judith, Fenichel, Patrick, Fleming, Lora E, Ferrier-Pages, Christine, Fordham, Richard, Gozt, Aleksandra, Griffin, Carly, Hahn, Mark E, Haryanto, Budi, Hixson, Richard, Ianelli, Hannah, James, Bryan D, Kumar, Pushpam, Laborde, Amalia, Law, Kara Lavender, Martin, Keith, Mu, Jenna, Mulders, Yannick, Mustapha, Adetoun, Niu, Jia, Pahl, Sabine, Park, Yongjoon, Pedrotti, Maria-Luiza, Pitt, Jordan Avery, Ruchirawat, Mathuros, Seewoo, Bhedita Jaya, Spring, Margaret, Stegeman, John J, Suk, William, Symeonides, Christos, Takada, Hideshige, Thompson, Richard C, Vicini, Andrea, Wang, Zhanyun, Whitman, Ella, Wirth, David, Wolff, Megan, Yousuf, Aroub K, Dunlop, Sarah

“…Plastics have conveyed great benefits to humanity and made possible some of the most significant advances of modern civilization in fields as diverse as…”
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Predictive Value of Using Initial Versus Terminal Deceased Donor Creatinine to Calculate the Kidney Donor Risk Index by Chiles, Mariana C., MPH, Husain, S. Ali, MD, MPH, Skillen, Whitney, MPH, Lee, Samnang, BS, Carpenter, Dustin, MD, MPH, Pastan, Stephen O., MD, Patzer, Rachel E., PhD, MPH, Tanriover, Bekir, MD, MPH, Mohan, Sumit, MD, MPH

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Regulation and Function of Cyclin D2 in B Lymphocyte Subsets by Chiles, Thomas C

“…Abs produced by B lymphocytes play an essential role in humoral immunity against pathogens. This response is dependent upon the extent of genome replication,…”
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Chromosome 15q25 locus and genetic susceptibility to lung cancer, COPD, and smoking: Triple whammy effect in the ACRIN-NLST cohort sub-study (N=10,054) by Hopkins, R.J., Young, R.P., Duan, F., Greco, E., Chiles, C., Aberle, D., Gamble, G.

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Lung cancer screening and the effects of competing causes of death in the ACRIN-NLST sub-study by Hopkins, R.J., Young, R.P., Duan, F., Greco, E., Chiles, C., Aberle, D., Gamble, G.

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Stratification of NLST-ACRIN screening participants identifies the “sweet spot” of screening by identifying early stage lung cancers most amenable to curative surgery (N=10,054) by Young, R.P., Hopkins, R.J., Duan, F., Greco, E., Chiles, C., Aberle, D., Gamble, G.

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Pollution and children's health by Landrigan, Philip J., Fuller, Richard, Fisher, Samantha, Suk, William A., Sly, Peter, Chiles, Thomas C., Bose-O'Reilly, Stephan

“…The Lancet Commission on Pollution and Health found that pollution – air, water, soil, and chemical pollution - was responsible in 2016 for 940,000 deaths in…”
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Low-Dose CT Lung Cancer Screening Practices and Attitudes Among Primary Care Providers at an Academic Medical Center by Lewis, J, Petty, W.J, Tooze, J.A, Miller, D.P, Chiles, C, Miller, A.A, Weaver, K.E

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Optimizing non-radiative energy transfer in hybrid colloidal-nanocrystal/silicon structures by controlled nanopillar architectures for future photovoltaic cells by Seitz, O., Caillard, L., Nguyen, H. M., Chiles, C., Chabal, Y. J., Malko, A. V.

“…To optimize colloidal nanocrystals/Si hybrid structures, nanopillars are prepared and organized via microparticle patterning and Si etching. A monolayer of…”
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Inhibition of Cyclin-dependent Kinase-2 Induces Apoptosis in Human Diffuse Large B-cell Lymphomas by Faber, Anthony C., Chiles, Thomas C.

“…Cyclin-dependent kinase (cdk) inhibitors have the potential to induce growth arrest and apoptosis in cancer cells. The genes encoding cdks involved in G1-S…”
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Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain by Mukherjee, Purna, Mulrooney, Tiernan J, Marsh, Jeremy, Blair, Derek, Chiles, Thomas C, Seyfried, Thomas N

“…AMP-activated protein kinase (AMPK) is a known physiological cellular energy sensor and becomes phosphorylated at Thr-172 in response to changes in cellular…”
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Requirement for a hsp90 Chaperone-dependent MEK1/2-ERK Pathway for B Cell Antigen Receptor-induced Cyclin D2 Expression in Mature B Lymphocytes by Piatelli, Michael J., Doughty, Cheryl, Chiles, Thomas C.

“…A requirement for cyclin D2 in G1-to-S phase progression has been definitively established in mature B cells stimulated via the B cell antigen receptor (BCR)…”
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