Search Results - "CHIGNARD, Michel"
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Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway
Published in The Journal of immunology (1950) (15-02-2008)“…Influenza A virus (IAV) triggers a contagious respiratory disease that produces considerable lethality. Although this lethality is likely due to an excessive…”
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Contribution of the Ade Resistance-Nodulation-Cell Division-Type Efflux Pumps to Fitness and Pathogenesis of Acinetobacter baumannii
Published in mBio (31-05-2016)“…Overexpression of chromosomal resistance-nodulation-cell division (RND)-type efflux systems with broad substrate specificity contributes to multidrug…”
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Cutting Edge: Influenza A Virus Activates TLR3-Dependent Inflammatory and RIG-I-Dependent Antiviral Responses in Human Lung Epithelial Cells
Published in The Journal of immunology (1950) (15-03-2007)“…Influenza A virus (IAV) triggers a contagious acute respiratory disease that causes considerable mortality annually. Recently, we established a role for the…”
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Involvement of Toll-like Receptor 3 in the Immune Response of Lung Epithelial Cells to Double-stranded RNA and Influenza A Virus
Published in The Journal of biological chemistry (18-02-2005)“…Influenza A is a highly contagious single-stranded RNA virus that infects both the upper and lower respiratory tracts of humans. The host innate immune…”
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Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia
Published in PLoS pathogens (01-06-2006)“…Influenza A virus (IAV) is the etiological agent of a highly contagious acute respiratory disease that causes epidemics and considerable mortality annually…”
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Deletion of the α-(1,3)-glucan synthase genes induces a restructuring of the conidial cell wall responsible for the avirulence of Aspergillus fumigatus
Published in PLoS pathogens (01-11-2013)“…α-(1,3)-Glucan is a major component of the cell wall of Aspergillus fumigatus, an opportunistic human fungal pathogen. There are three genes (AGS1, AGS2 and…”
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Pseudomonas aeruginosa LPS or flagellin are sufficient to activate TLR-dependent signaling in murine alveolar macrophages and airway epithelial cells
Published in PloS one (06-10-2009)“…The human lung is exposed to a large number of airborne pathogens as a result of the daily inhalation of 10,000 liters of air. Innate immunity is thus…”
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Editorial: Innovative Therapeutic and Vaccine Approaches Against Respiratory Pathogens
Published in Frontiers in immunology (17-12-2019)Get full text
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A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity
Published in PloS one (10-12-2013)“…Aspergillus fumigatus is an important allergen and opportunistic pathogen. Similarly to many other pathogens, it is able to produce lectins that may be…”
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Staphylococcus aureus Adenosine Inhibits sPLA2-IIA-Mediated Host Killing in the Airways
Published in The Journal of immunology (1950) (01-06-2015)“…Staphylococcus aureus is a common cause of bacterial infections in respiratory diseases. It secretes molecules to dampen host immunity, and the recently…”
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Control of Pseudomonas aeruginosa in the Lung Requires the Recognition of Either Lipopolysaccharide or Flagellin
Published in The Journal of immunology (1950) (01-07-2008)“…Acute lung infection due to Pseudomonas aeruginosa is an increasingly serious problem that results in high mortality especially in the compromised host. In…”
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Toll-like receptor 5 (TLR5), IL-1β secretion, and asparagine endopeptidase are critical factors for alveolar macrophage phagocytosis and bacterial killing
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2012)“…A deficit in early clearance of Pseudomonas aeruginosa (P. aeruginosa) is crucial in nosocomial pneumonia and in chronic lung infections. Few studies have…”
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Bronchial Epithelial Cells from Cystic Fibrosis Patients Express a Specific Long Non-coding RNA Signature upon Pseudomonas aeruginosa Infection
Published in Frontiers in cellular and infection microbiology (29-05-2017)“…( ) is the leading cause of chronic lung infection in Cystic Fibrosis (CF) patients. It is well recognized that CF epithelial cells fail to develop an…”
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critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system
Published in Proceedings of the National Academy of Sciences - PNAS (16-01-2007)“…Listeria monocytogenes is a human intracellular pathogen that is able to survive in the gastrointestinal environment and replicate in macrophages, thus…”
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Influenza A induces the major secreted airway mucin MUC5AC in a protease-EGFR-extracellular regulated kinase-Sp1-dependent pathway
Published in American journal of respiratory cell and molecular biology (01-08-2012)“…Mucins, the main glycoproteins present within mucus, modulate the rheologic properties of airways and participate in lung defense. They are thought to be able…”
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Differences in Patterns of Infection and Inflammation for Corticosteroid Treatment and Chemotherapy in Experimental Invasive Pulmonary Aspergillosis
Published in Infection and Immunity (01-01-2005)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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CHAC1 Is Differentially Expressed in Normal and Cystic Fibrosis Bronchial Epithelial Cells and Regulates the Inflammatory Response Induced by Pseudomonas aeruginosa
Published in Frontiers in immunology (29-11-2018)“…In cystic fibrosis (CF), ( ) colonizes the lungs, leading to chronic inflammation of the bronchial epithelium. ChaC glutathione-specific…”
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Protective Role of LGP2 in Influenza Virus Pathogenesis
Published in The Journal of infectious diseases (15-07-2014)“…Influenza A virus triggers a contagious respiratory disease that can cause considerable morbidity and mortality. Using an in vitro approach, we previously…”
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Normal and Cystic Fibrosis Human Bronchial Epithelial Cells Infected with Pseudomonas aeruginosa Exhibit Distinct Gene Activation Patterns
Published in PloS one (20-10-2015)“…In cystic fibrosis (CF), Pseudomonas aeruginosa is not eradicated from the lower respiratory tract and is associated with epithelial inflammation that…”
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A crucial role of Flagellin in the induction of airway mucus production by Pseudomonas aeruginosa
Published in PloS one (02-07-2012)“…Pseudomonas aeruginosa is an opportunistic pathogen involved in nosocomial infections. Flagellin is a P. aeruginosa virulence factor involved in host response…”
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