Search Results - "CHIEFARI, E"

Gestational diabetes mellitus: an updated overview by Chiefari, E., Arcidiacono, B., Foti, D., Brunetti, A.

“…The clinical and public health relevance of gestational diabetes mellitus (GDM) is widely debated due to its increasing incidence, the resulting negative…”
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The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-γ (PPARγ) and thiazolidinedione-PPARγ agonists by Costa, V, Foti, D, Paonessa, F, Chiefari, E, Palaia, L, Brunetti, G, Gulletta, E, Fusco, A, Brunetti, A

“…The peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the nuclear hormone receptor superfamily. Ligand activation of PPARγ is associated with…”
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Transcriptional regulation of human insulin receptor gene by the high‐mobility group protein HMGI(Y) by BRUNETTI, ANTONIO, MANFIOLETTI, GUIDALBERTO, CHIEFARI, EUSEBIO, GOLDFINE, IRA D., FOTI, DANIELA

“…ABSTRACT We have previously identified two closely related nuclear binding proteins that specifically interact with two unique functional AT‐rich sequences of…”
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A novel mutation in the thyrotropin (TSH) receptor gene causing loss of TSH binding but constitutive receptor activation in a family with resistance to TSH by RUSSO, Diego, BETTERLE, Corrado, ARTURI, Franco, CHIEFARI, Eusebio, GIRELLI, Maria E, FILETTI, Sebastiano

“…Resistance to TSH is a syndrome due to reduced responsiveness of the thyroid gland to biologically active TSH. Inactivating mutations of the TSH receptor…”
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Long-term diabetic complications in elderly patients with variable levels of HMGA1 expression by Chiefari, E, Capula, C, Paonessa, F, Iiritano, S, Nocera, A, Arcidiacono, B, Possidente, K, Foti, D, Brunetti, A

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A Phe 486 thyrotropin receptor mutation in an autonomously functioning follicular carcinoma that was causing hyperthyroidism by Camacho, P, Gordon, D, Chiefari, E, Yong, S, DeJong, S, Pitale, S, Russo, D, Filetti, S

“…Hot nodules are rarely found to be carcinomas. We report a case of a nonmetastatic follicular carcinoma that presented as a hot nodule that was causing…”
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Similarities and differences in the phenotype of members of an italian family with hereditary non-autoimmune hyperthyroidism associated with an activating TSH receptor germline mutation by ARTURI, F, CHIEFARI, E, TUMINO, S, RUSSO, D, SQUATRITO, S, CHAZENBALK, G, PERSANI, L, RAPOPORT, B, FILETTI, S

“…Constitutively activating germline mutations of the TSH receptor (TSH-R) are considered the cause of hereditary non-autoimmune hyperthyroidism. In this study,…”
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The 3',5'-cyclic adenosine monophosphate response element binding protein (CREB) is functionally reduced in human toxic thyroid adenomas by Brunetti, A, Chiefari, E, Filetti, S, Russo, D

“…In human normal thyrocytes, the cAMP-responsive signaling pathway plays a central role in gene regulation, cell proliferation, and differentiation…”
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Molecular insights into TSH receptor abnormality and thyroid disease by RUSSO, D, ARTURI, F, CHIEFARI, E, FILETTI, S

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Evaluation of a DHPLC-based assay for rapid detection of RET germline mutations in Italian patients with medullary thyroid carcinoma by Torrente, I, Arturi, F, D'Aloiso, L, Colosimo, A, De Luca, A, Ferretti, E, Russo, D, Chiefari, E, Scarpelli, D, Bisceglia, M, Dallapiccola, B, Filetti, S

“…Causative gain-of-function mutations of the RET tyrosine-kinase receptor gene have been reported in more than 95% of inherited cases of medullary thyroid…”
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RET proto-oncogene mutation in a mixed medullary-follicular thyroid carcinoma by ORLANDI, F, CHIEFARI, E, CARACI, P, MUSSA, A, GONZATTO, I, DE GIULI, P, GIUFFRIDA, D, ANGELI, A, FILETTI, S

“…A case of a patient with an uncommon thyroid carcinoma, showing histological and immunohistochemical features of both follicular and parafollicular cells is…”
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Thyroid hyperfunctioning adenomas with and without Gsp/TSH receptor mutations show similar clinical features by Arturi, F, Capula, C, Chiefari, E, Filetti, S, Russo, D

“…Activating mutations of Gs alpha protein (gsp) and TSH receptor (TSH-R) identified in autonomously hyperfunctioning thyroid adenomas have been proposed as the…”
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Analysis of RET proto-oncogene abnormalities in patients with MEN 2A, MEN 2B, familial or sporadic medullary thyroid carcinoma by CHIEFARI, E, RUSSO, D, BRUNO, R, GIANNASIO, P, PONTECORVI, A, FILETTI, S, GIUFFRIDA, D, ZAMPA, G. A, MERINGOLO, D, ARTURI, F, CHIODINI, I, BIANCHI, D, ATTARD, M, TRISCHITTA, V

“…Medullary thyroid carcinoma (MTC) may occur either as a sporadic or familial (FMTC) disease. Multiple endocrine neoplasia (MEN) type 2, inherited as an…”
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A large family with hereditary MTC: role of RET genetic analysis in differential diagnosis between MEN 2A and FMTC by Chiefari, E, Chiarella, R, Crocetti, U, Tardio, B, Arturi, F, Russo, D, Trischitta, V, Filetti, S, Zingrillo, M

“…Germline mutations of the RET proto-oncogene cause three different cancer syndromes: multiple endocrine neoplasia type 2A (MEN 2A), multiple endocrine…”
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Functional Variants of the HMGA1 Gene and Type 2 Diabetes Mellitus by Chiefari, Eusebio, Tanyolaç, Sinan, Paonessa, Francesco, Pullinger, Clive R, Capula, Carmelo, Iiritano, Stefania, Mazza, Tommaso, Forlin, Michele, Fusco, Alfredo, Durlach, Vincent, Durlach, Anne, Malloy, Mary J, Kane, John P, Heiner, Steven W, Filocamo, Mirella, Foti, Daniela P, Goldfine, Ira D, Brunetti, Antonio

“…CONTEXT High-mobility group A1 (HMGA1) protein is a key regulator of insulin receptor (INSR) gene expression. We previously identified a functional HMGA1 gene…”
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Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice by Brunetti, Antonio, Foti, Daniela, Chiefari, Eusebio, Fedele, Monica, Iuliano, Rodolfo, Brunetti, Leonardo, Paonessa, Francesco, Manfioletti, Guidalberto, Barbetti, Fabrizio, Brunetti, Arturo, Croce, Carlo M, Fusco, Alfredo

“…Type 2 diabetes mellitus is a widespread disease, affecting millions of people globally. Although genetics and environmental factors seem to have a role, the…”
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A Nucleoprotein Complex Containing Sp1, C/EBPβ, and HMGI-Y Controls Human Insulin Receptor Gene Transcription by Foti, Daniela, Iuliano, Rodolfo, Chiefari, Eusebio, Brunetti, Antonio

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation? by Chiefari, Eusebio, Brunetti, Antonio, Arturi, Franco, Bidart, Jean-Michel, Russo, Diego, Schlumberger, Martin, Filetti, Sebastiano

“…Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of…”
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Iodide symporter gene expression in human thyroid tumors by ARTURI, F, RUSSO, D, SCHLUMBERGER, M, DU VILLARD, J.-A, CAILLOU, B, VIGNERI, P, WICKER, R, CHIEFARI, E, SUAREZ, H. G, FILETTI, S

“…Expression of the Na+/I- symporter (NIS) gene was investigated by RT-PCR in a selected series of 26 primary thyroid carcinomas (19 papillary, 5 follicular, and…”
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Familial Medullary Thyroid Carcinoma: Clinical Variability and Low Aggressiveness Associated with RET Mutation at Codon 804 by Lombardo, Francesca, Baudin, Eric, Chiefari, Eusebio, Arturi, Franco, Bardet, Stephane, Caillou, Bernard, Conte, Chiara, Dallapiccola, Bruno, Giuffrida, Dario, Bidart, Jean-Michel, Schlumberger, Martin, Filetti, Sebastiano

“…Sixty-one heterozygotes harboring the germline V804L mutation of the RET protooncogene were identified in five independent families. A total of 31 subjects…”
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