Search Results - "CHIARIELLO, Massimo"

Endothelial dysfunction: A key to the pathophysiology and natural history of peripheral arterial disease? by Brevetti, Gregorio, Schiano, Vittorio, Chiariello, Massimo

“…Abstract Dysfunctional endothelium plays a crucial role in all stages of atherosclerosis and thus the accurate assessment of this organ is a valuable tool,…”
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Adjunctive mechanical devices to prevent distal embolization in patients undergoing mechanical revascularization for acute myocardial infarction: A meta-analysis of randomized trials by De Luca, Giuseppe, MD, Suryapranata, Harry, MD, Stone, Gregg W., MD, Antoniucci, David, MD, Neumann, Franz-Joseph, MD, Chiariello, Massimo, MD

“…Background The benefits of adjunctive mechanical devices to prevent distal embolization in patients with acute myocardial infarction (AMI) are still a matter…”
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Calcium channel blockers and cardiovascular outcomes: a meta-analysis of 175 634 patients by Costanzo, Pierluigi, Perrone-Filardi, Pasquale, Petretta, Mario, Marciano, Caterina, Vassallo, Enrico, Gargiulo, Paola, Paolillo, Stefania, Petretta, Andrea, Chiariello, Massimo

“…OBJECTIVEThe aim of this study was to assess the effect of calcium channel blocker (CCB) treatment, compared with other drugs or placebo/top of therapy, on…”
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Coronary stenting versus balloon angioplasty for acute myocardial infarction: A meta-regression analysis of randomized trials by De Luca, Giuseppe, Suryapranata, Harry, Stone, Gregg W, Antoniucci, David, Biondi-Zoccai, Giuseppe, Kastrati, Adnan, Chiariello, Massimo, Marino, Paolo

“…Abstract Introduction Although stenting has been shown to reduce the need for target vessel revascularization (TVR) in acute myocardial infarction (AMI), the…”
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Omega-3 polyunsaturated fatty acid in peripheral arterial disease: Effect on lipid pattern, disease severity, inflammation profile, and endothelial function by Schiano, Vittorio, Laurenzano, Eugenio, Brevetti, Gregorio, De Maio, Julieta Isabel, Lanero, Simona, Scopacasa, Francesco, Chiariello, Massimo

“…Summary Background & aims Peripheral arterial disease (PAD) is strongly associated with endothelial dysfunction and inflammation, which portend a high…”
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AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress by Perrino, Cinzia, Feliciello, Antonio, Schiattarella, Gabriele G., Esposito, Giovanni, Guerriero, Rosalia, Zaccaro, Laura, Del Gatto, Annarita, Saviano, Michele, Garbi, Corrado, Carangi, Rosa, Di Lorenzo, Emilio, Donato, Giuseppe, Indolfi, Ciro, Avvedimento, Vittorio Enrico, Chiariello, Massimo

“…Aims The aim of the present study was to determine the function and the role of the scaffold protein AKAP121, tethering cAMP dependent protein kinase A to the…”
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Cardiotoxic effects, or lack thereof, of anti-ErbB2 immunoagents by Riccio, Gennaro, Esposito, Giovanni, Leoncini, Emanuela, Contu, Riccardo, Condorelli, Gianluigi, Chiariello, Massimo, Laccetti, Paolo, Hrelia, Silvana, D'Alessio, Giuseppe, De Lorenzo, Claudia

“…This study investigated potential cardiotoxicity as exerted by Erbicin-derived-immunoagents (EDIAs), novel human anti-ErbB2 immunoagents engineered by fusion…”
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The role of neopterin in cardiovascular disease by Pacileo, Mario, Cirillo, Plinio, De Rosa, Salvatore, Ucci, Grazia, Petrillo, Gianluca, Musto D'Amore, Sergio, Sasso, Laura, Maietta, Paola, Spagnuolo, Raffaele, Chiariello, Massimo

“…Inflammation plays a key role in the initiation and progression of atherosclerosis but also in the pathophysiology of atheromatous plaque disruption and the…”
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Reactive oxygen species and antioxidants in the pathophysiology of cardiovascular disease: does the actual knowledge justify a clinical approach? by De Rosa, Salvatore, Cirillo, Plinio, Paglia, Antonella, Sasso, Laura, Di Palma, Vito, Chiariello, Massimo

“…There is evidence that reactive oxygen species (ROS) are related to the development of cardiovascular disease (CVD). Results from many studies support the…”
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Clinical impact of sirolimus-eluting stent in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials by Piscione, Federico, Piccolo, Raffaele, Cassese, Salvatore, Galasso, Gennaro, Chiariello, Massimo

“…Objectives: To evaluate outcome of patients undergoing sirolimus‐eluting stent (SES) as compared to bare‐metal stent (BMS) implantation during primary…”
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The extent of irreversible myocardial damage and the potential for left ventricular repair after primary percutaneous coronary intervention by Esposito, Giovanni, MD, PhD, Dellegrottaglie, Santo, MD, PhD, Chiariello, Massimo, MD

“…Primary percutaneous coronary intervention (PCI) is currently recognized as a highly effective therapy for acute myocardial infarction (AMI) and has been shown…”
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Myocardial collagen turnover in hypertrophic cardiomyopathy by LOMBARDI, Raffaella, BETOCCHI, Sandro, LOSI, Maria Angela, TOCCHETTI, Carlo Gabriele, AVERSA, Mariano, MIRANDA, Marianna, D'ALESSANDRO, Gianluigi, CACACE, Alessandra, CIAMPI, Quirino, CHIARIELLO, Massimo

“…Myocardial interstitial fibrosis is a characteristic of hypertrophic cardiomyopathy (HCM). This study evaluates the collagen turnover in HCM and its impact on…”
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Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure by Galasso, Gennaro, De Rosa, Roberta, Piscione, Federico, Iaccarino, Guido, Vosa, Carlo, Sorriento, Daniela, Piccolo, Raffaele, Rapacciuolo, Antonio, Walsh, Kenneth, Chiariello, Massimo

“…Aims Several studies have shown that muscle mass loss is an important pathogenic issue in heart failure (HF). Atrogin‐1 is a F‐box protein selectively…”
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Prognostic Significance of Left Atrial Volume Dilatation in Patients with Hypertrophic Cardiomyopathy by Losi, Maria-Angela, MD, Betocchi, Sandro, MD, Barbati, Giovanni, MD, Parisi, Valentina, MD, Tocchetti, Carlo-Gabriele, MD, Pastore, Fabio, MD, Migliore, Teresa, MD, Contaldi, Carla, MD, Caputi, Armando, MD, Romano, Rosalba, MD, Chiariello, Massimo, MD

“…To evaluate the prognostic role of left atrial (LA) volume in hypertrophic cardiomyopathy (HCM), LA volume was measured at baseline and during follow-up in 140…”
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Pro-atherothrombotic effects of leptin in human coronary endothelial cells by Cirillo, Plinio, Angri, Valeria, De Rosa, Salvatore, Calì, Gaetano, Petrillo, Gianluca, Maresca, Fabio, D'Ascoli, Greta-Luana, Maietta, Paola, Brevetti, Linda, Chiariello, Massimo

“…Adipocytes are nowadays recognised as cells able to produce and secrete a large variety of active substances termed adipokines, which exert direct effects on…”
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Effects of Exercise Training on High-Mobility Group Box-1 Levels After Acute Myocardial Infarction by Giallauria, Francesco, MD, PhD, Cirillo, Plinio, MD, PhD, D’agostino, Mariantonietta, MD, Petrillo, Gianluca, MD, Vitelli, Alessandra, MD, Pacileo, Mario, MD, Angri, Valeria, MD, Chiariello, Massimo, MD, Vigorito, Carlo, MD

“…Abstract Background High-mobility group box-1 (HMGB1) is a novel predictor of adverse postinfarction clinical outcomes, playing a crucial role in the…”
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Prevention of distal embolization in patients undergoing mechanical revascularization for acute myocardial infarction. A review of current status by De Luca, Giuseppe, Suryapranata, Harry, Chiariello, Massimo

“…Distal embolization is a relatively common complication in primary angioplasty and is associated with poor perfusion and higher mortality. The aim of this…”
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Effects of Ile164 Polymorphism of Beta2 -Adrenergic Receptor Gene on Coronary Artery Disease by Piscione, Federico, MD, Iaccarino, Guido, MD, Galasso, Gennaro, MD, Cipolletta, Ersilia, MD, Rao, Maria Assunta, MD, Brevetti, Gregorio, MD, Piccolo, Raffaele, MD, Trimarco, Bruno, MD, Chiariello, Massimo, MD

“…Objectives This study investigated the relationship between beta2 -adrenergic receptor (B2AR) Ile164 polymorphism and coronary artery disease (CAD). Background…”
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Concomitant coronary and peripheral arterial disease: Relationship between the inflammatory status of the affected limb and the severity of coronary artery disease by Brevetti, Gregorio, MD, Piscione, Federico, MD, Schiano, Vittorio, MD, Galasso, Gennaro, MD, Scopacasa, Francesco, PhD, Chiariello, Massimo, MD

“…Objective In coronary artery disease (CAD), concomitant peripheral arterial disease (PAD) entails increased systemic inflammatory profile and more severe…”
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In concomitant coronary and peripheral arterial disease, inflammation of the affected limbs predicts coronary artery endothelial dysfunction by Brevetti, Gregorio, Piscione, Federico, Cirillo, Plinio, Galasso, Gennaro, Schiano, Vittorio, Barbato, Emanuele, Scopacasa, Francesco, Chiariello, Massimo

“…Abstract Background In coronary artery disease (CAD), concomitant peripheral arterial disease (PAD) entails more severe coronary atherosclerosis. We…”
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