Search Results - "CHIANG, P"

Systematic Evaluation of Drug-Disease Relationships to Identify Leads for Novel Drug Uses by Chiang, AP, Butte, AJ

“…Drug repositioning refers to the discovery of alternative uses for drugs—uses that are different from that for which the drugs were originally intended. One…”
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Tumor cell intravasation by Chiang, Serena P H, Cabrera, Ramon M, Segall, Jeffrey E

“…The process of entering the bloodstream, intravasation, is a necessary step in the development of distant metastases. The focus of this review is on the…”
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Characterization of Stellar and Substellar Members in the Coma Berenices Star Cluster by Tang, Shih-Yun, Chen, W. P., Chiang, P. S., Jose, Jessy, Herczeg, Gregory J., Goldman, Bertrand

“…We have identified stellar and substellar members in the nearby star cluster Coma Berenices, using photometry, proper motions, and distances of a combination…”
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Discovery and preclinical validation of drug indications using compendia of public gene expression data by Sirota, Marina, Dudley, Joel T, Kim, Jeewon, Chiang, Annie P, Morgan, Alex A, Sweet-Cordero, Alejandro, Sage, Julien, Butte, Atul J

“…The application of established drug compounds to new therapeutic indications, known as drug repositioning, offers several advantages over traditional drug…”
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Survival and Long-term Outcomes Following Bioprosthetic vs Mechanical Aortic Valve Replacement in Patients Aged 50 to 69 Years by Chiang, Yuting P, Chikwe, Joanna, Moskowitz, Alan J, Itagaki, Shinobu, Adams, David H, Egorova, Natalia N

“…IMPORTANCE: The choice between bioprosthetic and mechanical aortic valve replacement in younger patients is controversial because long-term survival and major…”
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Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets by Suthram, Silpa, Dudley, Joel T, Chiang, Annie P, Chen, Rong, Hastie, Trevor J, Butte, Atul J

“…Current work in elucidating relationships between diseases has largely been based on pre-existing knowledge of disease genes. Consequently, these studies are…”
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Antibody Response to a Fourth Dose of a SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients: A Case Series by Alejo, Jennifer L., Mitchell, Jonathan, Chiang, Teresa P.-Y., Abedon, Aura T., Boyarsky, Brian J., Avery, Robin K., Tobian, Aaron A.R., Levan, Macey L., Massie, Allan B., Garonzik-Wang, Jacqueline M., Segev, Dorry L., Werbel, William A.

“…Supplemental Digital Content is available in the text…”
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Prevalence and Durability of SARS-CoV-2 Antibodies Among Unvaccinated US Adults by History of COVID-19 by Alejo, Jennifer L, Mitchell, Jonathan, Chang, Amy, Chiang, Teresa P. Y, Massie, Allan B, Segev, Dorry L, Makary, Martin A

“…As of Dec 28, 2021, approximately 27% of the US population was unvaccinated against SARS-CoV-2, yet the prevalence of natural immunity remains unknown. Blood…”
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Antibody Response to the Janssen COVID-19 Vaccine in Solid Organ Transplant Recipients by Boyarsky, Brian J., Chiang, Teresa P.-Y., Ou, Michael T., Werbel, William A., Massie, Allan B., Segev, Dorry L., Garonzik-Wang, Jacqueline M.

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Survival and Outcomes Following Bioprosthetic vs Mechanical Mitral Valve Replacement in Patients Aged 50 to 69 Years by Chikwe, Joanna, Chiang, Yuting P, Egorova, Natalia N, Itagaki, Shinobu, Adams, David H

“…IMPORTANCE: In nonelderly patients with mitral disease requiring valve replacement, deciding between bioprosthetic and mechanical prosthetic valves is…”
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Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease by Dudley, Joel T, Sirota, Marina, Shenoy, Mohan, Pai, Reetesh K, Roedder, Silke, Chiang, Annie P, Morgan, Alex A, Sarwal, Minnie M, Pasricha, Pankaj Jay, Butte, Atul J

“…Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract for which there are few safe and effective therapeutic…”
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Implementing a QCancer risk tool into general practice consultations: an exploratory study using simulated consultations with Australian general practitioners by Chiang, P P-C, Glance, D, Walker, J, Walter, F M, Emery, J D

“…Background: Reducing diagnostic delays in primary care by improving the assessment of symptoms associated with cancer could have significant impacts on cancer…”
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Response to “COVID‐19 in SOT versus non‐SOT” by Avery, Robin K., Chiang, Teresa P.‐Y., Marr, Kieren A., Garonzik‐Wang, Jacqueline, Segev, Dorry L., Massie, Allan B.

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Novel CRB1 pathogenic variant in Chuuk families with Leber congenital amaurosis by Albakri, Amani, Pisuchpen, Phattrawan, Capasso, Jenina E., Schneider, Adele, Kopinsky, Sarina, Glaser, Tom, Chiang, John P.‐W., Yomai, Anamaria Akapito, McNear, Donna, Levin, Alex V.

“…The purpose of this article is to determine the cause of Leber congenital amaurosis (LCA) in Chuuk state, Federated States of Micronesia (FSM). In this…”
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Frequency and risk factors of non-retinopathy ocular conditions in people with diabetes: the Singapore Malay Eye Study by Chiang, P. P.-C., Lamoureux, E. L., Zheng, Y., Tay, W. T., Mitchell, P., Wang, J. J., Wong, T. Y.

“…Aim To investigate the frequency and risk factors of non‐retinopathy ocular conditions in persons with diabetes. Methods A population‐based cross‐sectional…”
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Retinal ganglion cell neuronal damage in diabetes and diabetic retinopathy by Ng, Dorothy SK, Chiang, Peggy PC, Tan, Gavin, Cheung, CM Gemmy, Cheng, Ching-Yu, Cheung, Carol Y, Wong, Tien Y, Lamoureux, Ecosse L, Ikram, Mohammad K

“…Background To examine the association of diabetes and diabetic retinopathy (DR) with retinal ganglion cell (RGC) loss. Design Observational case–control study…”
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Predicting Adverse Drug Reactions Using Publicly Available PubChem BioAssay Data by Pouliot, Y, Chiang, AP, Butte, AJ

“…Adverse drug reactions (ADRs) can have severe consequences, and therefore the ability to predict ADRs prior to market introduction of a drug is desirable…”
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Cr(VI) Removal on Fungal Biomass of Neurospora crassa: the Importance of Dissolved Organic Carbons Derived from the Biomass to Cr(VI) Reduction by Hsu, L.C, Wang, S.L, Lin, Y.C, Wang, M.K, Chiang, P.N, Liu, J.C, Kuan, W.H, Chen, C.C, Tzou, Y.M

“…Interactions of toxic Cr(VI) with renewable biomaterials are considered an important pathway for Cr(VI) removal in ecosystems. Biomaterials are susceptible to…”
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Long-Term Risk for Aortic Complications After Aortic Valve Replacement in Patients With Bicuspid Aortic Valve Versus Marfan Syndrome by Itagaki, Shinobu, MD, Chikwe, Joanna P., MD, Chiang, Yuting P., BA, Egorova, Natalia N., PhD, Adams, David H., MD

“…Abstract Background Bicuspid aortic valves are associated with valve dysfunction, ascending aortic aneurysm and dissection. Management of the ascending aorta…”
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Extracorporeal Membrane Oxygenation in Postcardiotomy Cardiogenic Shock by Akbik, Bassel, Chou, Lin-Chiang P, Gorthi, Janardhana

“…Postcardiotomy extracorporeal membrane oxygenation (PC-ECMO), the most frequent indication for ECMO in the United States, is increasingly used as the…”
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