Search Results - "CHIANALE, Federica"

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice by Porporato, Paolo E, Filigheddu, Nicoletta, Reano, Simone, Ferrara, Michele, Angelino, Elia, Gnocchi, Viola F, Prodam, Flavia, Ronchi, Giulia, Fagoonee, Sharmila, Fornaro, Michele, Chianale, Federica, Baldanzi, Gianluca, Surico, Nicola, Sinigaglia, Fabiola, Perroteau, Isabelle, Smith, Roy G, Sun, Yuxiang, Geuna, Stefano, Graziani, Andrea

“…Cachexia is a wasting syndrome associated with cancer, AIDS, multiple sclerosis, and several other disease states. It is characterized by weight loss, fatigue,…”
Get full text

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures by Cerruti, Benedetta, Puliafito, Alberto, Shewan, Annette M, Yu, Wei, Combes, Alexander N, Little, Melissa H, Chianale, Federica, Primo, Luca, Serini, Guido, Mostov, Keith E, Celani, Antonio, Gamba, Andrea

“…The growth of a well-formed epithelial structure is governed by mechanical constraints, cellular apico-basal polarity, and spatially controlled cell division…”
Get full text

The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness by Rainero, Elena, Cianflone, Cristina, Porporato, Paolo Ettore, Chianale, Federica, Malacarne, Valeria, Bettio, Valentina, Ruffo, Elisa, Ferrara, Michele, Benecchia, Fabio, Capello, Daniela, Paster, Wolfgang, Locatelli, Irene, Bertoni, Alessandra, Filigheddu, Nicoletta, Sinigaglia, Fabiola, Norman, Jim C, Baldanzi, Gianluca, Graziani, Andrea

“…Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We…”
Get full text

Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells by Filigheddu, Nicoletta, Gnocchi, Viola F, Coscia, Marco, Cappelli, Miriam, Porporato, Paolo E, Taulli, Riccardo, Traini, Sara, Baldanzi, Gianluca, Chianale, Federica, Cutrupi, Santina, Arnoletti, Elisa, Ghè, Corrado, Fubini, Alberto, Surico, Nicola, Sinigaglia, Fabiola, Ponzetto, Carola, Muccioli, Giampiero, Crepaldi, Tiziana, Graziani, Andrea

“…Ghrelin is an acylated peptidyl gastric hormone acting on the pituitary and hypothalamus to stimulate appetite, adiposity, and growth hormone release, through…”
Get full text

Diacylglycerol kinases are essential for hepatocyte growth factor‐dependent proliferation and motility of Kaposi’s sarcoma cells by Baldanzi, Gianluca, Pietronave, Stefano, Locarno, Deborah, Merlin, Simone, Porporato, Paolo, Chianale, Federica, Filigheddu, Nicoletta, Cantelmo, Anna Rita, Albini, Adriana, Graziani, Andrea, Prat, Maria

“…Hepatocyte growth factor (HGF) is involved in the pathogenesis of Kaposi’s sarcoma (KS), the most frequent neoplasia in patients with AIDS, characterized by…”
Get full text

Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI by Chianale, Federica, Rainero, Elena, Cianflone, Cristina, Bettio, Valentina, Pighini, Andrea, Porporato, Paolo E, Filigheddu, Nicoletta, Serini, Guido, Sinigaglia, Fabiola, Baldanzi, Gianluca, Graziani, Andrea

“…Diacylglycerol kinases (DGKs) convert diacylglycerol (DAG) into phosphatidic acid (PA), acting as molecular switches between DAG- and PA-mediated signaling. We…”
Get full text

Diacylglycerol Kinase is Required for HGF-induced Invasiveness and Anchorage-independent Growth of MDA-MB-231 Breast Cancer Cells by FILIGHEDDU, Nicoletta, CUTRUPI, Santina, GRAZIANI, Andrea, SURICO, Nicola, PORPORATO, Paolo Ettore, RIBONI, Francesca, BALDANZI, Gianluca, CHIANALE, Federica, FORTINA, Elisabetta, PIANTANIDA, Paola, DE BORTOLI, Michele, VACCA, Giovanni

“…Background: Estrogen receptor (ER)-negative breast cancers have a worse prognosis than ER-positive cancers, being more aggressive and overexposed to stimuli…”
Get full text

PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction by Gagliardi, Paolo Armando, di Blasio, Laura, Puliafito, Alberto, Seano, Giorgio, Sessa, Roberto, Chianale, Federica, Leung, Thomas, Bussolino, Federico, Primo, Luca

“…Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response,…”
Get full text

Three-dimensional chemotaxis-driven aggregation of tumor cells by Puliafito, Alberto, De Simone, Alessandro, Seano, Giorgio, Gagliardi, Paolo Armando, Di Blasio, Laura, Chianale, Federica, Gamba, Andrea, Primo, Luca, Celani, Antonio

“…One of the most important steps in tumor progression involves the transformation from a differentiated epithelial phenotype to an aggressive, highly motile…”
Get full text

Real-time monitoring of cell protrusion dynamics by impedance responses by Gagliardi, Paolo Armando, Puliafito, Alberto, di Blasio, Laura, Chianale, Federica, Somale, Desiana, Seano, Giorgio, Bussolino, Federico, Primo, Luca

“…Cellular protrusions are highly dynamic structures involved in fundamental processes,including cell migration and invasion. For a cell to migrate, its leading…”
Get full text

PDK1-mediated activation of MRCK[alpha] regulates directional cell migration and lamellipodia retraction by Gagliardi, Paolo Armando, di Blasio, Laura, Puliafito, Alberto, Seano, Giorgio, Sessa, Roberto, Chianale, Federica, Leung, Thomas, Bussolino, Federico, Primo, Luca

“…Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response,…”
Get full text

SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling by Baldanzi, Gianluca, Pighini, Andrea, Bettio, Valentina, Rainero, Elena, Traini, Sara, Chianale, Federica, Porporato, Paolo E, Filigheddu, Nicoletta, Mesturini, Riccardo, Song, Shuping, Schweighoffer, Tamas, Patrussi, Laura, Baldari, Cosima T, Zhong, Xiao-Ping, van Blitterswijk, Wim J, Sinigaglia, Fabiola, Nichols, Kim E, Rubio, Ignacio, Parolini, Ornella, Graziani, Andrea

“…Diacylglycerol kinases (DGKs) metabolize diacylglycerol to phosphatidic acid. In T lymphocytes, DGKα acts as a negative regulator of TCR signaling by…”
Get full text

Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30 by Filigheddu, Nicoletta, Sampietro, Sara, Chianale, Federica, Porporato, Paolo E., Gaggianesi, Miriam, Gregnanin, Ilaria, Rainero, Elena, Ferrara, Michele, Perego, Beatrice, Riboni, Francesca, Baldanzi, Gianluca, Graziani, Andrea, Surico, Nicola

“…Increased levels of endogenous and/or exogenous estrogens are one of the well known risk factors of endometrial cancer. Diacylglycerol kinases (DGKs) are a…”
Get full text

8-Prenylnaringenin inhibits epidermal growth factor-induced MCF-7 breast cancer cell proliferation by targeting phosphatidylinositol-3-OH kinase activity by Brunelli, Elisa, Pinton, Giulia, Chianale, Federica, Graziani, Andrea, Appendino, Giovanni, Moro, Laura

“…8-Prenylnaringenin (8PN), one of the strongest plant-derived oestrogen receptors (ERs) ligand, has been suggested to have potential cancer chemo-preventive…”
Get full text

The Diacylglycerol Kinase [alpha]/Atypical PKC/[beta]1 Integrin Pathway in SDF-1[alpha] Mammary Carcinoma Invasiveness by Rainero, Elena, Cianflone, Cristina, Porporato, Paolo Ettore, Chianale, Federica, Malacarne, Valeria, Bettio, Valentina, Ruffo, Elisa, Ferrara, Michele, Benecchia, Fabio, Capello, Daniela, Paster, Wolfgang, Locatelli, Irene, Bertoni, Alessandra, Filigheddu, Nicoletta, Sinigaglia, Fabiola, Norman, Jim C, Baldanzi, Gianluca, Graziani, Andrea

“…Diacylglycerol kinase [alpha] (DGK[alpha]), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix…”
Get full text

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures by Cerruti, Benedetta, Puliafito, Alberto, Shewan, Annette M., Yu, Wei, Combes, Alexander N., Little, Melissa H., Chianale, Federica, Primo, Luca, Serini, Guido, Mostov, Keith E., Celani, Antonio, Gamba, Andrea

Get full text

Diacylglycerol kinase [alpha] mediates 17-[beta]-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30 by Filigheddu, Nicoletta, Sampietro, Sara, Chianale, Federica, Porporato, Paolo E, Gaggianesi, Miriam, Gregnanin, Ilaria, Rainero, Elena, Ferrara, Michele, Perego, Beatrice, Riboni, Francesca, Baldanzi, Gianluca, Graziani, Andrea, Surico, Nicola

“…Increased levels of endogenous and/or exogenous estrogens are one of the well known risk factors of endometrial cancer. Diacylglycerol kinases (DGKs) are a…”
Get full text

Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling by Chianale, Federica, Cutrupi, Santina, Rainero, Elena, Baldanzi, Gianluca, Porporato, Paolo E, Traini, Sara, Filigheddu, Nicoletta, Gnocchi, Viola F, Santoro, Massimo M, Parolini, Ornella, van Blitterswijk, Wim J, Sinigaglia, Fabiola, Graziani, Andrea

“…Diacylglycerol kinases (Dgk) phosphorylate diacylglycerol (DG) to phosphatidic acid (PA), thus turning off and on, respectively, DG-mediated and PA-mediated…”
Get full text

Diacylglycerol kinase a mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI by Chianale, Federica, Rainero, Elena, Cianflone, Cristina, Bettio, Valentina, Pighini, Andrea, Porporato, Paolo E, Filigheddu, Nicoletta, Serini, Guido, Sinigaglia, Fabiola, Baldanzi, Gianluca, Graziani, Andrea

“…Diacylglycerol kinases (DGKs) convert diacylglycerol (DAG) into phosphatidic acid (PA), acting as molecular switches between DAG- and PA-mediated signaling. We…”
Get full text

Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI by Chianale, Federica, Rainero, Elena, Cianflone, Cristina, Bettio, Valentina, Pighini, Andrea, Porporato, Paolo E, Filigheddu, Nicoletta, Serini, Guido, Sinigaglia, Fabiola, Baldanzi, Gianluca, Graziani, Andrea

“…Diacylglycerol kinases (DGKs) convert diacylglycerol (DAG) into phosphatidic acid (PA), acting as molecular switches between DAG- and PA-mediated signaling. We…”
Get full text