Search Results - "CHHALLIYIL, Pradheepkumar"
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Cleistanthin A causes DNA strand breaks and induces apoptosis in cultured cells
Published in Mutation research (24-01-2000)“…Cleistanthin A is a novel anticancer agent isolated from Cleistanthus collinus (Rox B). It caused chromatid aberrations in a dose dependent manner. However,…”
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ETV6-AML1 translocation breakpoints cluster near a purine/pyrimidine repeat region in the ETV6 gene
Published in Blood (1999)“…The t(12;21)(p13;q22) translocation, fusing the ETV6 and AML1 genes, is the most frequent chromosomal translocation associated with pediatric B-cell precursor…”
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Mechanisms of MLL gene rearrangement: site-specific DNA cleavage within the breakpoint cluster region is independent of chromosomal context
Published in Human molecular genetics (15-10-2001)“…The MLL gene at chromosome band 11q23 is specifically cleaved at a unique site within its breakpoint cluster region (bcr) during the higher order chromatin…”
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ETV6-AML1 Translocation Breakpoints Cluster Near a Purine/Pyrimidine Repeat Region in the ETV6 Gene
Published in Blood (01-01-1999)“…The t(12;21)(p13;q22) translocation, fusing the ETV6 andAML1 genes, is the most frequent chromosomal translocation associated with pediatric B-cell precursor…”
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Journal Article -
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Anticancer potential of cleistanthin A isolated from the tropical plant Cleistanthus collinus
Published in Oncology research (1999)“…A diphyllin glycoside called cleistanthin A was isolated from the tropical plant Cleistanthus collinus and its anticancer potential was assessed. This compound…”
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