Search Results - "CHESSELLS, J. M"

A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases by HASLE, H, NIEMEYER, C. M, CHESSELLS, J. M, BAUMANN, I, BENNETT, J. M, KERNDRUP, G, HEAD, D. R

“…Myelodysplastic and myeloproliferative disorders are rare in childhood and there is no widely accepted system for their diagnosis and classification. We…”
Get full text

Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements by PUI, C-H, CHESSELLS, J. M, HARHOTT, J, HARMS, D. O, HARRISON, C. J, HARRISON, P. L, HEEREMA, N, JANKA-SCHAUB, G, KAMPS, W, MASERA, G, PULLEN, J, RAIMONDI, S. C, CAMITTA, B, RICHARDS, S, RIEHM, H, SALLAN, S, SATHER, H, SHUSTER, J, SILVERMAN, L. B, VALSECCHI, M. G, VILMER, E, ZHOU, Y, GAYNON, P. S, BARUCHEL, A, SCHRAPPE, M, BIONDI, A, BOYETT, J. M, CARROLL, A, EDEN, O. B, EVANS, W. E, GADNER, H

“…To assess the clinical heterogeneity among patients with acute lymphoblastic leukemia (ALL) and various 11q23 abnormalities, we analyzed data on 497 infants,…”
Get full text

Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997 by EDEN, O. B, HARRISON, G, RICHARDS, S, LILLEYMAN, J. S, BAILEY, C. C, CHESSELLS, J. M, HANN, I. M, HILL, F. G. H, GIBSON, B. E. S

“…Results of three consecutive completed UK trials (1980-1997) for childhood lymphoblastic leukaemia are presented. National accrual has progressively increased…”
Get full text

Pediatric myelodysplasia : a study of 68 children and a new prognostic scoring system by PASSMORE, S. J, HANN, I. M, STILLER, C. A, RAMANI, P, SWANSBURY, G. J, GIBBONS, B, REEVES, B. R, CHESSELLS, J. M

“…Clinical, morphologic, and cytogenetic features were examined in a group of 68 children with myelodysplasia (MDS) referred to a single institution between…”
Get full text

Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party by CHESSELLS, J. M, HARRISON, C. J, KEMPSKI, H, WEBB, Dkii, WHEATLEY, K, HANN, I. M, STEVENS, R. F, HARRISON, G, GIBSON, B. E

“…The clinical features, cytogenetics and response to treatment have been examined in 180 infants (aged <1 year) with acute leukaemia; 118 with acute…”
Get full text

The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL X and XA compared : a report from the MRC paediatric and adult working parties by CHESSELLS, J. M, HALL, E, PRENTICE, H. G, DURRANT, J, BAILEY, C. C, RICHARDS, S. M

“…The purpose of the study was to examine the influence of age on outcome in a large cohort of children and adults with lymphoblastic leukaemia who were treated…”
Get full text

Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987–1999 by Chessells, J. M., Harrison, C. J., Watson, S. L., Vora, A. J., Richards, S. M.

“…One hundred and twenty‐six infants with acute lymphoblastic leukaemia (ALL) were treated on two consecutive protocols, Infant 87 (n = 40) and Infant 92 (n =…”
Get full text

RELAPSED LYMPHOBLASTIC LEUKAEMIA IN CHILDREN: A CONTINUING CHALLENGE by Chessels, Judith M.

Get full text

Down's syndrome and acute lymphoblastic leukaemia: clinical features and response to treatment by Chessells, J M, Harrison, G, Richards, S M, Bailey, C C, Hill, F G H, Gibson, B E, Hann, I M

“…AIMS To examine the clinical and biological features of acute lymphoblastic leukaemia in children with Down's syndrome (DS), to compare their survival with…”
Get full text

Neurofibromatosis and childhood leukaemia/lymphoma: a population-based UKCCSG study by Stiller, C A, Chessells, J M, Fitchett, M

“…There is a well-known raised risk of leukaemia in children with neurofibromatosis type 1 (NF-1). We carried out the first detailed population-based study of…”
Get full text

Progressive reduction in treatment‐related deaths in Medical Research Council childhood lymphoblastic leukaemia trials from 1980 to 1997 (UKALL VIII, X and XI) by Hargrave, D. R., Hann, I. M., Richards, S. M., Hill, F. G., Lilleyman, J. S., Kinsey, S., Bailey, C. C., Chessells, J. M., Mitchell, C., Eden, O. B.

“…In the last 20 years, the survival rate for children with acute lymphoblastic leukaemia (ALL) has markedly improved, largely owing to a decrease in relapses…”
Get full text

Haematological abnormalities in Shwachman-Diamond syndrome by Smith, O P, Hann, I M, Chessells, J M, Reeves, B R, Milla, P

“…We have analysed the haematological parameters in 21 patients with Shwachman-Diamond syndrome (SDS) seen over a 25-year period at our institution. Neutropenia,…”
Get more information

Cytogenetics and prognosis in childhood lymphoblastic leukaemia: results of MRC UKALL X by Chessells, J. M., Swansbury, G. J., Reeves, B., Bailey, C. C., Richards, S. M.

“…We have analysed the prognostic influence of cytogenetic findings at diagnosis in a group of 502 children with acute lymphoblastic leukaemia (ALL), treated on…”
Get full text

A polymerase chain reaction study of the stability of Ig heavy-chain and T-cell receptor δ gene rearrangements between presentation and relapse of childhood B-lineage acute lymphoblastic leukemia by STEWARD, C. G, GOULDEN, N. J, KATZ, F, BAINES, D, MARTIN, P. G, LANGLANDS, K, POTTER, M. N, CHESSELLS, J. M, OAKHILL, A

“…Ig heavy-chain (IgH) and partial V delta 2-D delta 3 T-cell receptor (TCR) gene rearrangements were investigated, by polymerase chain reaction (PCR)…”
Get full text

Intellectual performance after presymptomatic cranial radiotherapy for leukaemia: effects of age and sex by Christie, D, Leiper, A D, Chessells, J M, Vargha-Khadem, F

“…Cognitive outcome, as measured by verbal and performance IQs, was compared in 35 girls and 47 boys who were in first remission for acute lymphoblastic…”
Get full text

Improved outcome of acute myeloid leukaemia in Down’s syndrome by Craze, J L, Harrison, G, Wheatley, K, Hann, I M, Chessells, J M

“…OBJECTIVE To review the clinical features, treatment, and outcome of children in the UK with Down’s syndrome and acute myeloid leukaemia (AML). DESIGN A…”
Get full text

Late effects of intensive treatment for acute myeloid leukemia and myelodysplasia in childhood by Liesner, R J, Leiper, A D, Hann, I M, Chessells, J M

“…To perform a comprehensive assessment of the late effects of short-term intensive chemotherapy for childhood acute myeloid leukemia (AML) and myelodysplasia,…”
Get more information

Recent advances in management of acute leukaemia by Chessells, Judith M

“…There have been significant improvements in the outlook for children with acute leukaemia but these advances are only available to a minority of the world's…”
Get full text

Bone marrow transplantation versus chemotherapy in the treatment of very high–risk childhood acute lymphoblastic leukemia in first remission: results from Medical Research Council UKALL X and XI by Wheeler, Kate A., Richards, Susan M., Bailey, Clifford C., Gibson, Brenda, Hann, Ian M., Hill, Frank G.H., Chessells, Judith M.

“…The role of bone marrow transplantation (BMT) in first remission of children with high-risk acute lymphoblastic leukemia (ALL) remains unclear. There were 3676…”
Get full text

Treatment related deaths during induction and in first remission in acute lymphoblastic leukaemia: MRC UKALL X by Wheeler, K, Chessells, J M, Bailey, C C, Richards, S M

“…The benefits of achieving a long term event free survival of 60-70% by using increasingly intense treatment regimens must be weighed against the increased risk…”
Get full text