Search Results - "CHERIAN, S. P"

Modulation of paclitaxel resistance by annexin IV in human cancer cell lines by HAN, E. K.-H, TAHIR, S. K, CHERIAN, S. P, COLLINS, N, NG, S.-C

“…A recurring problem with cancer therapies is the development of drug resistance. While investigating the protein profile of cells resistant to a novel…”
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Modulation of drug resistance by α-tubulin in paclitaxel-resistant human lung cancer cell lines by Han, E. Kyu-Ho, Gehrke, L., Tahir, S.K., Credo, R.B., Cherian, S.P., Sham, H., Rosenberg, S.H., Ng, S.-C.

“…Beta(β)-tubulin isotype variation has recently been implicated in the modulation of resistance to paclitaxel in human lung cancer cells and in primary human…”
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Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis by BRENTNALL, T. A, CRISPIN, D. A, BRONNER, M. P, CHERIAN, S. P, HUEFFED, M, RABINOVITCH, P. S, RUBIN, C. E, HAGGITT, R. C, BOLAND, C. R

“…Microsatellite instability (MIN) has been detected in many cancer types; however, recently we also observed it in the nonneoplastic but inflammatory setting of…”
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Effect of novel CAAX peptidomimetic farnesyltransferase inhibitor on angiogenesis in vitro and in vivo by Gu, W.-Z, Tahir, S.K, Wang, Y.-C, Zhang, H.-C, Cherian, S.P, O'Connor, S, Leal, J.A, Rosenberg, S.H, Ng, S.-C

“…Ras oncogenes can contribute to tumour development by stimulating vascular endothelial growth factor (VEGF)-dependent angiogenesis. The effect of Ras on…”
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Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesis by Macdonald, Graeme A., Greenson, Joel K., Saito, Koji, Cherian, Sajeev P., Appelman, Henry D., Boland, C. Richard

“…DNA mismatch repair is an important mechanism involved in maintaining the fidelity of genomic DNA. Defective DNA mismatch repair is implicated in a variety of…”
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Reduced potassium currents in old rat CA1 hippocampal neurons by Alshuaib, W.B., Hasan, S.M., Cherian, S.P., Mathew, M.V., Hasan, M.Y., Fahim, M.A.

“…Potassium currents are an important factor in repolarizing the membrane potential and determining the level of neuronal excitability. We compared potassium…”
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Unusual Case of Acute Posteromedial Papillary Muscle Rupture After Acute Anterior Myocardial Infarction by Cherian, P.S., MBBS, Clarke, A.J.B., FRACS, Burstow, D.J., FRACP

“…Papillary muscle rupture is now a rare complication of acute myocardial infarction. Posteromedial papillary muscle rupture is more common than anterolateral…”
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In vitro transcription/translation assay for the screening of hMLH1 and hMSH2 mutations in familial colon cancer by Luce, M C, Marra, G, Chauhan, D P, Laghi, L, Carethers, J M, Cherian, S P, Hawn, M, Binnie, C G, Kam-Morgan, L N, Cayouette, M C

“…Hereditary nonpolyposis colorectal cancer (HNPCC) has been linked recently to a defect in repairing mismatched nucleotides in DNA. The aim of this study was to…”
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Inhibition of farnesyltransferase with A-176120, a novel and potent farnesyl pyrophosphate analogue by Tahir, S.K, Gu, W.-Z, Zhang, H.-C, Leal, J, Lee, J.Y, Kovar, P, Saeed, B, Cherian, S.P, Devine, E, Cohen, J, Warner, R, Wang, Y.-C, Stout, D, Arendsen, D.L, Rosenberg, S, Ng, S.-C

“…Farnesylation of Ras is required for its transforming activity in human cancer and the reaction is catalysed by the enzyme farnesyltransferase. Recently, we…”
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Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation by Koi, M, Umar, A, Chauhan, D P, Cherian, S P, Carethers, J M, Kunkel, T A, Boland, C R

“…The human colon tumor cell line HCT 116 is known to have a homozygous mutation in the mismatch repair gene hMLH1 on human chromosome 3, to exhibit…”
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DRUG EFFECTS ON CALCIUM HOMEOSTASIS IN MOUSE CA1 HIPPOCAMPAL NEURONS by ALSHUAIB, WALEED B., CHERIAN, SUSAN P., HASAN, MOHAMED Y., FAHIM, MOHAMED A.

“…Voltage-dependent Ca2+ channels (VDCC) are important in control of neuronal excitability, synaptic transmission, and many other cellular process. Even the…”
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INCREASED CALCIUM INFLUX THROUGH ACETYLCHOLINE RECEPTORS IN DUNCE NEURONS by ALSHUAIB, WALEED B., HASAN, MOHAMED, CHERIAN, SUSAN P., FAHIM, MOHAMED A.

“…Calcium homeostasis was studied in dunce, a Drosophila mutant that is defective in learning and memory. Fura 2-AM fluorescence photometry was used to measure…”
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Modulation of neuronal [Ca super(2+)] sub(i) by caffeine is altered with aging by Alshuaib, W B, Cherian, S P, Hasan, MY, Fahim, MA

“…Voltage-dependent calcium channels play an important role in controlling many neuronal processes such as neuronal excitability and synaptic transmission. Any…”
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Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-vitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation by KOI, M, ASAD UMAR, CHAUHAN, D. P, CHERIAN, S. P, CARETHERS, J. M, KUNKEL, T. A, BOLAND, C. R

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