Search Results - "CHERBAVAZ, Diana B"

A 17-gene Assay to Predict Prostate Cancer Aggressiveness in the Context of Gleason Grade Heterogeneity, Tumor Multifocality, and Biopsy Undersampling by Klein, Eric A, Cooperberg, Matthew R, Magi-Galluzzi, Cristina, Simko, Jeffry P, Falzarano, Sara M, Maddala, Tara, Chan, June M, Li, Jianbo, Cowan, Janet E, Tsiatis, Athanasios C, Cherbavaz, Diana B, Pelham, Robert J, Tenggara-Hunter, Imelda, Baehner, Frederick L, Knezevic, Dejan, Febbo, Phillip G, Shak, Steven, Kattan, Michael W, Lee, Mark, Carroll, Peter R

“…Abstract Background Prostate tumor heterogeneity and biopsy undersampling pose challenges to accurate, individualized risk assessment for men with localized…”
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The 21-gene Recurrence Score® assay predicts distant recurrence in lymph node-positive, hormone receptor-positive, breast cancer patients treated with adjuvant sequential epirubicin- and docetaxel-based or epirubicin-based chemotherapy (PACS-01 trial) by Penault-Llorca, Frédérique, Filleron, Thomas, Asselain, Bernard, Baehner, Frederick L, Fumoleau, Pierre, Lacroix-Triki, Magali, Anderson, Joseph M, Yoshizawa, Carl, Cherbavaz, Diana B, Shak, Steven, Roca, Lise, Sagan, Christine, Lemonnier, Jérôme, Martin, Anne-Laure, Roché, Henri

“…The 21-gene Recurrence Score (RS) result predicts outcome and chemotherapy benefit in node-negative and node-positive (N+), estrogen receptor-positive (ER+)…”
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Characterization and functionality of proliferative human Sertoli cells by Chui, Kitty, Trivedi, Alpa, Cheng, C Yan, Cherbavaz, Diana B, Dazin, Paul F, Huynh, Ai Lam Thu, Mitchell, James B, Rabinovich, Gabriel A, Noble-Haeusslein, Linda J, John, Constance M

“…It has long been thought that mammalian Sertoli cells are terminally differentiated and nondividing postpuberty. For most previous in vitro studies immature…”
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Analytical validation of the Oncotype DX prostate cancer assay - a clinical RT-PCR assay optimized for prostate needle biopsies by Knezevic, Dejan, Goddard, Audrey D, Natraj, Nisha, Cherbavaz, Diana B, Clark-Langone, Kim M, Snable, Jay, Watson, Drew, Falzarano, Sara M, Magi-Galluzzi, Cristina, Klein, Eric A, Quale, Christopher

“…The Oncotype DX Prostate Cancer Assay is a multi-gene RT-PCR expression assay that was developed for use with fixed paraffin-embedded (FPE) diagnostic prostate…”
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Validation of the 21-gene test as a predictor of clinical response to neoadjuvant hormonal therapy for ER+, HER2-negative breast cancer: the TransNEOS study by Iwata, Hiroji, Masuda, Norikazu, Yamamoto, Yutaka, Fujisawa, Tomomi, Toyama, Tatsuya, Kashiwaba, Masahiro, Ohtani, Shoichiro, Taira, Naruto, Sakai, Takehiko, Hasegawa, Yoshie, Nakamura, Rikiya, Akabane, Hiromitsu, Shibahara, Yukiko, Sasano, Hironobu, Yamaguchi, Takuhiro, Sakamaki, Kentaro, Bailey, Helen, Cherbavaz, Diana B., Jakubowski, Debbie M., Sugiyama, Naoko, Chao, Calvin, Ohashi, Yasuo

“…Purpose The Recurrence Score test is validated to predict benefit of adjuvant chemotherapy. TransNEOS, a translational study of New Primary Endocrine-therapy…”
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A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by breast-conserving surgery alone by Rakovitch, Eileen, Nofech-Mozes, Sharon, Hanna, Wedad, Baehner, Frederick L., Saskin, Refik, Butler, Steven M., Tuck, Alan, Sengupta, Sandip, Elavathil, Leela, Jani, Prashant A., Bonin, Michel, Chang, Martin C., Robertson, Susan J., Slodkowska, Elzbieta, Fong, Cindy, Anderson, Joseph M., Jamshidian, Farid, Miller, Dave P., Cherbavaz, Diana B., Shak, Steven, Paszat, Lawrence

“…Validated biomarkers are needed to improve risk assessment and treatment decision-making for women with ductal carcinoma in situ (DCIS) of the breast. The Onco…”
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21-Gene Recurrence Score and Locoregional Recurrence in Node-Positive/ER-Positive Breast Cancer Treated With Chemo-Endocrine Therapy by Mamounas, Eleftherios P, Liu, Qing, Paik, Soonmyung, Baehner, Frederick L, Tang, Gong, Jeong, Jong-Hyeon, Kim, S Rim, Butler, Steven M, Jamshidian, Farid, Cherbavaz, Diana B, Sing, Amy P, Shak, Steven, Julian, Thomas B, Lembersky, Barry C, Wickerham, D Lawrence, Costantino, Joseph P, Wolmark, Norman

“…The 21-gene recurrence score (RS) predicts risk of locoregional recurrence (LRR) in node-negative, estrogen receptor (ER)-positive breast cancer. We evaluated…”
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Multigene Expression Assay and Benefit of Radiotherapy After Breast Conservation in Ductal Carcinoma in Situ by Rakovitch, Eileen, Nofech-Mozes, Sharon, Hanna, Wedad, Sutradhar, Rinku, Baehner, Frederick L, Miller, Dave P, Fong, Cindy, Gu, Sumei, Tuck, Alan, Sengupta, Sandip, Elavathil, Leela, Jani, Prashant A, Bonin, Michel, Chang, Martin C, Slodkowska, Elzbieta, Anderson, Joseph M, Cherbavaz, Diana B, Shak, Steven, Paszat, Lawrence

“…Most women with ductal carcinoma in situ (DCIS) will receive breast-conserving surgery (BCS) and radiation (RT). RT can be omitted for women at low risk of…”
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A Multigene Expression Assay to Predict Local Recurrence Risk for Ductal Carcinoma In Situ of the Breast by SOLIN, Lawrence J, GRAY, Robert, DAVIDSON, Nancy E, INGLE, James N, PEREZ, Edith A, WOOD, William C, SPARANO, Joseph A, BADVE, Sunil, BAEHNER, Frederick L, BUTLER, Steven M, HUGHES, Lorie L, YOSHIZAWA, Carl, CHERBAVAZ, Diana B, SHAK, Steven, PAGE, David L, SLEDGE, George W

“…For women with ductal carcinoma in situ (DCIS) of the breast, the risk of developing an ipsilateral breast event (IBE; defined as local recurrence of DCIS or…”
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21-Gene Recurrence Score for prognosis and prediction of taxane benefit after adjuvant chemotherapy plus endocrine therapy: results from NSABP B-28/NRG Oncology by Mamounas, Eleftherios P., Tang, Gong, Paik, Soonmyung, Baehner, Frederick L., Liu, Qing, Jeong, Jong-Hyeon, Kim, S. Rim, Butler, Steven M., Jamshidian, Farid, Cherbavaz, Diana B., Sing, Amy P., Shak, Steven, Julian, Thomas B., Lembersky, Barry C., Lawrence Wickerham, D., Costantino, Joseph P., Wolmark, Norman

“…Background The 21-gene recurrence score (RS) predicts outcome and benefit from adjuvant chemotherapy benefit in breast cancer patients treated with adjuvant…”
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A Prospective Comparison of the 21-Gene Recurrence Score and the PAM50-Based Prosigna in Estrogen Receptor-Positive Early-Stage Breast Cancer by Alvarado, Michael D., Prasad, Che, Rothney, Megan, Cherbavaz, Diana B., Sing, Amy P., Baehner, Frederick L., Svedman, Christer, Markopoulos, Christos J.

“…Introduction The 21-gene Recurrence Score ® assay (Onco type DX ® , Genomic Health, Inc.) is a validated predictor of recurrence risk/chemotherapy benefit in…”
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Gene expression in normal-appearing tissue adjacent to prostate cancers are predictive of clinical outcome: evidence for a biologically meaningful field effect by Magi-Galluzzi, Cristina, Maddala, Tara, Falzarano, Sara Moscovita, Cherbavaz, Diana B, Zhang, Nan, Knezevic, Dejan, Febbo, Phillip G, Lee, Mark, Lawrence, Hugh Jeffrey, Klein, Eric A

“…We evaluated gene expression in histologically normal-appearing tissue (NT) adjacent to prostate tumor in radical prostatectomy specimens, assessing for…”
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Metal Coordination-Based Inhibitors of Adenylyl Cyclase:  Novel Potent P-Site Antagonists by Levy, Daniel E, Bao, Ming, Cherbavaz, Diana B, Tomlinson, James E, Sedlock, David M, Homcy, Charles J, Scarborough, Robert M

“…The adenylyl cyclases (ACs) are a family of intracellular enzymes associated with signal transduction by virtue of their ability to convert ATP to cAMP. The…”
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Access to Phosphorylation in Isocitrate Dehydrogenase May Occur by Domain Shifting by Finer-Moore, Janet, Tsutakawa, Susan E, Cherbavaz, Diana B, LaPorte, David C, Koshland, Daniel E, Stroud, Robert M

“…To clarify further the mechanism of regulation by phosphorylation of isocitrate dehydrogenase, cocrystallization of isocitrate dehydrogenase and isocitrate…”
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Agonist-induced calcium response in single human platelets assayed in a microfluidic device by Tran, Louie, Farinas, Javier, Ruslim-Litrus, Lily, Conley, Pamela B., Muir, Craig, Munnelly, Kevin, Sedlock, David M., Cherbavaz, Diana B.

“…To facilitate drug discovery directed toward platelet-specific targets, we developed a platelet isolation and fluorophore-loading method that yields…”
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Discovery of ADDL--targeting small molecule drugs for Alzheimer's disease by Look, Gary C, Jerecic, Jasna, Cherbavaz, Diana B, Pray, Todd R, Breach, Jean-Claude R, Crosier, Walter J, Igoudin, Lev, Hironaka, Catherine M, Lowe, Raymond M, McEntee, Michele, Ruslim-Litrus, Lily, Wu, Hsiu-Mei, Zhang, Sue, Catalano, Susan M, Goure, William F, Summa, David, Krafft, Grant A

“…Amyloid beta-derived diffusible ligands (ADDLs) comprise the neurotoxic subset of soluble Abeta(1-42) oligomers, now widely considered to be the molecular…”
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Hydroxamate based inhibitors of adenylyl cyclase. Part 1: The effect of acyclic linkers on P-site binding by Levy, Daniel E, Marlowe, Charles, Kane-Maguire, Kim, Bao, Ming, Cherbavaz, Diana B, Tomlinson, James E, Sedlock, David M, Scarborough, Robert M

“…The adenylyl cyclases (ACs) are a family of enzymes that are key elements of signal transduction by virtue of their ability to convert ATP to cAMP. The…”
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Active site water molecules revealed in the 2.1 Å resolution structure of a site-directed mutant of isocitrate dehydrogenase 1 1Edited by I. A. Wilson by Cherbavaz, Diana B, Lee, Myoung E, Stroud, Robert M, Koshland, Daniel E

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A pilot laboratory study comparing the 21-gene assay and PAM50-ROR by Prasad, Che, Rothney, Megan, Cherbavaz, Diana B., Sing, Amy P., Baehner, Frederick L., Svedman, Christer, Markopoulos, Christos

“…Abstract only…”
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The development of the DCIS score: Scaling and normalization in the Marin General Hospital cohort by Baehner, Frederick L., Butler, Steven M, Yoshizawa, Carl N., Prasad, Che, Cherbavaz, Diana B., Jamshidian, Farid, Shak, Steven

“…Abstract only 190 Background: In selected low-risk patients with DCIS treated with wide local excision without radiation, the DCIS score was validated as a…”
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