Search Results - "CHER, L"

Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis by Conley-LaComb, M Katie, Semaan, Louie, Singareddy, Rajareddy, Li, Yanfeng, Heath, Elisabeth I, Kim, Seongho, Cher, Michael L, Chinni, Sreenivasa R

“…The CXCL12/CXCR4 axis transactivates HER2 and promotes intraosseous tumor growth. To further explore the transactivation of HER2 by CXCL12, we investigated the…”
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Identification and quantification of nuisance odors at a trash transfer station by Curren, Jane, Hallis, Samantha A., Snyder, Cherie (Cher) L., Suffet, Irwin (Mel) H.

“…•The Odor Profile Method was successfully applied at a trash transfer station.•Municipal solid waste was the major odor source (rancid, sulfur, fragrant) by…”
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TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model by Semaan, Louie, Mander, Navneet, Cher, Michael L, Chinni, Sreenivasa R

“…Castrate Resistant Prostate Cancer (CRPC) is an advanced disease resistant to systemic traditional medical or surgical castration, and resistance is primarily…”
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Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM by Kong, Dejuan, Heath, Elisabeth, Chen, Wei, Cher, Michael L, Powell, Isaac, Heilbrun, Lance, Li, Yiwei, Ali, Shadan, Sethi, Seema, Hassan, Oudai, Hwang, Clara, Gupta, Nilesh, Chitale, Dhananjay, Sakr, Wael A, Menon, Mani, Sarkar, Fazlul H

“…The emergence of castrate-resistant prostate cancer (CRPC) contributes to the high mortality of patients diagnosed with prostate cancer (PCa), which in part…”
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PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling by Conley-LaComb, M Katie, Saliganan, Allen, Kandagatla, Pridvi, Chen, Yong Q, Cher, Michael L, Chinni, Sreenivasa R

“…The chemokine CXCL12, also known as SDF-1, and its receptor, CXCR4, are overexpressed in prostate cancers and in animal models of prostate-specific PTEN…”
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Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth by Govindarajan, Barani, Sbrissa, Diego, Pressprich, Mark, Kim, Seongho, Rishi, Arun K., Vaishampayan, Ulka, Cher, Michael L., Chinni, Sreenivasa R.

“…The chemokine receptor, CXCR4 signaling regulates cell growth, invasion, and metastasis to the bone-marrow niche in prostate cancer (PCa). Previously, we…”
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Prolonged disease control with MEK inhibitor in neurofibromatosis type I‐associated glioblastoma by Ameratunga, M., McArthur, G., Gan, H., Cher, L.

“…Summary What is known and objective Neurofibromatosis is associated with overactivation of the RAS‐MAPK pathway. MEK inhibitors have been shown to be an…”
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ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells by Powell, Katelyn, Semaan, Louie, Conley-LaComb, M Katie, Asangani, Irfan, Wu, Yi-Mi, Ginsburg, Kevin B, Williams, Julia, Squire, Jeremy A, Maddipati, Krishna R, Cher, Michael L, Chinni, Sreenivasa R

“…Intratumoral androgen synthesis in prostate cancer contributes to the development of castration-resistant prostate cancer (CRPC). Several enzymes responsible…”
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Five-year follow-up study of a population-based prospective cohort of men with low-risk prostate cancer: the treatment options in prostate cancer study (TOPCS): study protocol by Xu, Jinping, Goodman, Michael, Janisse, James, Cher, Michael L, Bock, Cathryn Hufford

“…IntroductionActive surveillance (AS) is recommended for men with low-risk prostate cancer (LRPC) to reduce overtreatment and to maintain patients’ quality of…”
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Upgrading on Per Protocol versus For Cause surveillance prostate biopsies: An opportunity to decreasing the burden of active surveillance by Wang, Michael, Lange, Andrew, Perlman, David, Qi, Ji, George, Arvin K., Ferrante, Stephanie, Semerjian, Alice, Sarle, Richard, Cher, Michael L., Ginsburg, Kevin B.

“…Background Most prostate cancer (PC) active surveillance (AS) protocols recommend “Per Protocol” surveillance biopsy (PPSBx) every 1–3 years, even if clinical…”
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Platelet‐Derived Growth Factor‐D Overexpression Contributes to Epithelial‐Mesenchymal Transition of PC3 Prostate Cancer Cells by Kong, Dejuan, Wang, Zhiwei, Sarkar, Sarah H., Li, Yiwei, Banerjee, Sanjeev, Saliganan, Allen, Kim, Hyeong‐Reh Choi, Cher, Michael L., Sarkar, Fazlul H.

“…The majority of human malignancies are believed to have epithelial origin, and the progression of cancer is often associated with a transient process named…”
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CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12 by Chinni, Sreenivasa R., Sivalogan, Sivasakthy, Dong, Zhong, Filho, J. Carlos Trindade, Deng, Xiyun, Bonfil, R. Daniel, Cher, Michael L.

“…BACKGROUND Hematopoietic cells home to bone by means of chemo‐attraction to marrow chemokines, and interaction of chemokines with their receptors leads to the…”
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CXCL12/CXCR4 Transactivates HER2 in Lipid Rafts of Prostate Cancer Cells and Promotes Growth of Metastatic Deposits in Bone by Chinni, Sreenivasa R, Yamamoto, Hamilto, Dong, Zhong, Sabbota, Aaron, Bonfil, R Daniel, Cher, Michael L

“…Chemokines and their receptors function in migration and homing of cells to target tissues. Recent evidence suggests that cancer cells use a chemokine receptor…”
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Outcomes from the use of computerized neurocognitive testing in a recurrent glioblastoma clinical trial by Field, K.M., Barnes, E.H., Sim, H.W., Nowak, A.K., Simes, J., Rosenthal, M.A., Wheeler, H., Hovey, E.J., Cher, L.M.

“…•Neurocognitive function is an important endpoint in brain tumor trials.•We tested Cogstate computerized testing in a recurrent glioblastoma clinical…”
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Shedding of RANKL by Tumor-Associated MT1-MMP Activates Src-Dependent Prostate Cancer Cell Migration by SABBOTA, Aaron L, CHOI KIM, Hyeong-Reh, XIAONING ZHE, FRIDMAN, Rafael, BONFIL, R. Daniel, CHER, Michael L

“…Membrane type 1 matrix metalloproteinase (MT1-MMP) plays an essential role in protease-mediated extracellular matrix (ECM) degradation, but it also functions…”
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Comparison of two standard odor intensity evaluation methods for odor problems in air or water by CURREN, Jane, SNYDER, Cherie L, ABRAHAM, Samantha, SUFFET, I. H

“…Government agencies responsible for ensuring healthful water and/or air quality are often faced with resolving public complaints of nuisance odors…”
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Transcriptional regulation of CXCR4 in prostate cancer: significance of TMPRSS2-ERG fusions by Singareddy, Rajareddy, Semaan, Louie, Conley-Lacomb, M Katie, St John, Jason, Powell, Katelyn, Iyer, Matthew, Smith, Daryn, Heilbrun, Lance K, Shi, Dongping, Sakr, Wael, Cher, Michael L, Chinni, Sreenivasa R

“…CXCR4 is a chemokine receptor that mediates invasion and metastasis. CXCR4 expression is transcriptionally regulated in cancer cells and is associated with…”
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Does the type of cryoprobe affect oncological and functional outcomes in men with clinically localized prostate cancer treated with primary whole gland prostate cryoablation? by Taha, Tarek, Tan, Wei Phin, Elshafei, Ahmed, Aminsharifi, Alireza, Given, Robert, Cher, Michael L, Polascik, Thomas J

“…This study aimed to compare the oncological and functional outcomes of primary whole gland cryoablation of the prostate using the variable ice cryoprobe…”
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Maspin Expression Inhibits Osteolysis, Tumor Growth, and Angiogenesis in a Model of Prostate Cancer Bone Metastasis by Cher, Michael L., Biliran, Hector R., Bhagat, Sunita, Meng, Yonghong, Che, Mingxin, Lockett, Jaron, Abrams, Judith, Fridman, Rafael, Zachareas, Michael, Sheng, Shijie

“…Emerging evidence indicates that tumor-associated proteolytic remodeling of bone matrix may underlie the capacity of tumor cells to colonize and survive in the…”
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A novel function for platelet-derived growth factor D: induction of osteoclastic differentiation for intraosseous tumor growth by Huang, W, Fridman, Y, Bonfil, R D, Ustach, C V, Conley-LaComb, M K, Wiesner, C, Saliganan, A, Cher, M L, Kim, H-R C

“…Although increasing evidence suggests a critical role for platelet-derived growth factor (PDGF) receptor β (β-PDGFR) signaling in prostate cancer (PCa)…”
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