Search Results - "CHENJIN JIN"
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Activation of the UPR Protects against Cigarette Smoke-induced RPE Apoptosis through Up-Regulation of Nrf2
Published in The Journal of biological chemistry (27-02-2015)“…Recent studies have revealed a role of endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) in the regulation of RPE cell activity and…”
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2
Optic disc metastasis presenting as an initial sign of non-small-cell lung cancer: a case report
Published in Journal of international medical research (01-09-2020)“…Most intraocular metastases are detected in the choroid, iris, ciliary body, or retina. Conversely, tumors rarely metastasize to the optic disc, and they even…”
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Triptolide-nanoliposome-APRPG, a novel sustained-release drug delivery system targeting vascular endothelial cells, enhances the inhibitory effects of triptolide on laser-induced choroidal neovascularization
Published in Biomedicine & pharmacotherapy (01-11-2020)“…[Display omitted] •Intravitreal injections of triptolide inhibit choroidal neovascularization.•TP-nanolip-APRPG enhances the effects of triptolide on choroidal…”
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4
Nomogram-based prediction of clinically significant macular edema in diabetes mellitus patients
Published in Acta diabetologica (01-09-2022)“…Aims The aim of the study was to construct and validate a risk nomogram for clinically significant macular edema (CSME) prediction in diabetes mellitus (DM)…”
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5
Triptolide attenuates laser-induced choroidal neovascularization via M2 macrophage in a mouse model
Published in Biomedicine & pharmacotherapy (01-09-2020)“…[Display omitted] •Triptolide inhibits M2 type macrophage polarization in mice.•Triptolide exerts anti-angiogenic activities without toxicity in vivo and in…”
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6
ERp29 Attenuates Nicotine-Induced Endoplasmic Reticulum Stress and Inhibits Choroidal Neovascularization
Published in International journal of molecular sciences (01-11-2023)“…Nicotine-induced endoplasmic reticulum (ER) stress in retinal pigment epithelium (RPE) cells is thought to be one pathological mechanism underlying age-related…”
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Comparison of macular buckling and vitrectomy for the treatment of macular schisis and associated macular detachment in high myopia: a randomized clinical trial
Published in Acta ophthalmologica (Oxford, England) (01-05-2020)“…Objective To compare the efficacy and safety of macular buckling and vitrectomy for myopic traction maculopathy showing macular schisis (MS) and associated…”
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Comparison between non-visualized polyps and visualized polyps on optical coherence tomography angiography in polypoidal choroidal vasculopathy
Published in Graefe's archive for clinical and experimental ophthalmology (01-11-2019)“…Purpose To determine the underlying reasons for the non-visualization of polyps on en face optical coherence tomography angiography (OCTA) in patients with…”
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Deep learning for detecting retinal detachment and discerning macular status using ultra-widefield fundus images
Published in Communications biology (08-01-2020)“…Retinal detachment can lead to severe visual loss if not treated timely. The early diagnosis of retinal detachment can improve the rate of successful…”
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10
Retinal blood vessel segmentation based on Densely Connected U-Net
Published in Mathematical biosciences and engineering : MBE (15-04-2020)“…The segmentation of blood vessels from retinal images is an important and challenging task in medical analysis and diagnosis. This paper proposes a new…”
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Electroretinogram evaluation for the treatment of proliferative diabetic retinopathy by short-pulse pattern scanning laser panretinal photocoagulation
Published in Lasers in medical science (01-07-2018)“…Panretinal photocoagulation (PRP) is a standard method for proliferative diabetic retinopathy (PDR) treatment. However, conventional PRP usually significantly…”
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12
Erp29 Attenuates Cigarette Smoke Extract-Induced Endoplasmic Reticulum Stress and Mitigates Tight Junction Damage in Retinal Pigment Epithelial Cells
Published in Investigative ophthalmology & visual science (01-10-2015)“…Endoplasmic reticulum protein 29 (ERp29) is a novel chaperone that was recently found decreased in human retinas with AMD. Herein, we examined the effect of…”
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13
Laser Peripheral Iridotomy in Eyes with Narrow Drainage Angles: Ultrasound Biomicroscopy Outcomes. The Liwan Eye Study
Published in Ophthalmology (Rochester, Minn.) (01-08-2007)“…Purpose To assess the short-term effect of laser peripheral iridotomy (LPI) on anterior segment anatomy in angle-closure suspects using ultrasound…”
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14
Deep learning from “passive feeding” to “selective eating” of real-world data
Published in NPJ digital medicine (30-10-2020)“…Artificial intelligence (AI) based on deep learning has shown excellent diagnostic performance in detecting various diseases with good-quality clinical images…”
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Anatomical and functional responses in eyes with diabetic macular edema treated with "1 + PRN" ranibizumab: one-year outcomes in population of mainland China
Published in BMC ophthalmology (15-06-2020)“…To evaluate the anatomical and functional responses in eyes with diabetic macular edema (DME) treated with ranibizumab under "1 + pro re nata (PRN)" regimen…”
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Refractive error and risk of early or late age-related macular degeneration: a systematic review and meta-analysis
Published in PloS one (06-03-2014)“…To summarize relevant evidence investigating the associations between refractive error and age-related macular degeneration (AMD). Systematic review and…”
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Comparison of vascular parameters between normal cynomolgus macaques and healthy humans by optical coherence tomography angiography
Published in BMC ophthalmology (11-10-2019)“…The metabolic activity of retina is higher than other human tissues and is crucial to the vision. Cynomolgus macaques is widely used in ophthalmic disease…”
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Quantitative Analysis of Retinal Microvascular Changes after Conbercept Therapy in Branch Retinal Vein Occlusion Using Optical Coherence Tomography Angiography
Published in Ophthalmologica (Basel) (01-01-2019)“…To quantitatively evaluate microvascular changes in eyes with macular oedema due to branch retinal vein occlusion (BRVO) using optical coherence tomography…”
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Retinal and Choroidal Alterations in Diabetic Retinopathy Treatment using Subthreshold Panretinal Photocoagulation with Endpoint Management Algorithm: A Secondary Analysis of a Randomized Clinical Trial
Published in Ophthalmology and therapy (01-08-2023)“…Introduction The aim of this study was to compare retinal and choroidal alterations in eyes with severe nonproliferative diabetic retinopathy (NPDR) after…”
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Subthreshold Micropulse Laser vs. Conventional Laser for Central Serous Chorioretinopathy: A Randomized Controlled Clinical Trial
Published in Frontiers in medicine (16-07-2021)“…Purpose: To investigate the effectiveness and safety of 577-nm subthreshold micropulse laser (SML) on acute central serous chorioretinopathy (CSC). Methods:…”
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