Search Results - "CHENG-DER YU"

Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer by Chuang, Po-Kai, Hsiao, Michael, Hsu, Tsui-Ling, Chang, Chuan-Fa, Wu, Chung-Yi, Chen, Bo-Rui, Huang, Han-Wen, Liao, Kuo-Shiang, Chen, Chen-Chun, Chen, Chi-Long, Yang, Shun-Min, Kuo, Chiung Wen, Chen, Peilin, Chiu, Ping-Tzu, Chen, I-Ju, Lai, Jiann-Shiun, Yu, Cheng-Der Tony, Wong, Chi-Huey

“…The globo-series glycosphingolipids (GSLs) SSEA3, SSEA4, and Globo-H specifically expressed on cancer cells are found to correlate with tumor progression and…”
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Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction by Chang, Yu-Hsuan, Wu, Jen-Chine, Yu, Hui-Ming, Hsu, Hua-Ting, Wu, Ying-Ta, Yu, Alice Lin-Tsing, Yu, Cheng-Der Tony, Wong, Chi-Huey

“…Thrombin activates protease-activated receptor-1 (PAR-1) through binding to exosite I and the active site to promote tumor growth. We have developed a new…”
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Preclinical Studies of OBI-999: A Novel Globo H-Targeting Antibody-Drug Conjugate by Yang, Ming-Chen, Shia, Chi-Sheng, Li, Wan-Fen, Wang, Chun-Chung, Chen, I-Ju, Huang, Teng-Yi, Chen, Yu-Jung, Chang, Hui-Wen, Lu, Chi-Huan, Wu, Yueh-Chin, Wang, Nan-Hsuan, Lai, Jiann-Shiun, Yu, Cheng-Der, Lai, Ming-Tain

“…Globo H (GH), a hexasaccharide, is expressed at low levels in normal tissues but is highly expressed in multiple cancer types, rendering it a promising target…”
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Abstract 4815: Novel Globo H targeting antibody-drug conjugate with binding specificity and anti-tumor efficacy in multiple cancer types by Yang, Ming-Chen, Chen, Yu-Jung, Shia, Chi-Sheng, Chang, Hui-Wen, Li, Wan-Fen, Yu, Cheng-Der Tony, Chen, I-Ju

“…Abstract Background: Globo H, a hexasaccharide, has been reported to be highly expressed in multiple cancers types, but not express or, if at all, express to a…”
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Calculation of cutaneous metabolic rate constant from diffusion model by Yu, C D

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Effect of propylene glycol on subcutaneous absorption of a benzimidazole hydrochloride by Yu, C D, Kent, J S

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Transforming growth factor-α (TGF-α) in a semisolid dosage form : preservative and vehicle selection by TAN, E. L, SHAH, H. S, LEISTER, K. J, KOZICK, L. M, PASCIAK, P, VANDERLAAN, R. K, CHENG-DER YU, PATEL, B

“…The selection of an ideal semisolid vehicle for growth factors presents a challenge. Some antimicrobial agents are known to delay wound healing. The objective…”
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Cascade impactor method for the droplet size characterization of a metered-dose nasal spray by Yu, C D, Jones, R E, Henesian, M

“…A relatively rapid and simple method was developed to characterize the droplet size of a metered-dose nasal spray. The study primarily concerned the…”
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Physical model evaluation of topical prodrug delivery--simultaneous transport and bioconversion of vidarabine-5'-valerate IV: Distribution of esterase and deaminase enzymes in hairless mouse skin by Yu, C D, Fox, J L, Higuchi, W I, Ho, N F

“…A semiquantitative assessment of estrase and deaminase distributions in hairless mouse skin was performed in vitro. The enzyme activities were quantified using…”
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Physical model evaluation of topical prodrug delivery--simultaneous transport and bioconversion of vidarabine-5'-valerate V: Mechanistic analysis of influence of nonhomogeneous enzyme distributions in hairless mouse skin by Yu, C D, Gordon, N A, Fox, J L, Higuchi, W I, Ho, N F

“…The mathematical problem of simultaneous transport and metabolism in the case of nonuniform enzyme distributions in the skin was solved, and the solutions were…”
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Physical model evaluation of topical prodrug delivery--simultaneous transport and bioconversion of vidarabine-5'-valerate III: Permeability differences of vidarabine and n-pentanol in components of hairless mouse skin by Yu, C D, Higuchi, W I, Ho, N F, Fox, J L, Flynn, G L

“…The permeation behavior of 3H-vidarabine (3H-9-beta-D-ara-binofuranosyladenine) and 14C-n-pentanol through different strata of hairless mouse skin was studied…”
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Physical stability of a recombinant alphaI antitrypsin injection by CHENG-DER YU, ROOSDORP, N, SHAMIM PUSHPALA

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Physical model evaluation of topical prodrug delivery-simultaneous transport and bioconversion of vidarabine-5'-valerate I: Physical model development by Yu, C D, Fox, J L, Ho, N F, Higuchi, W I

“…A physical model approach to the topical delivery of a vidarabine ester prodrug was investigated. It involved modeling, theoretical simulations, experimental…”
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Endemic Burkholderia cepacia Bacteraemia: Clinical Features and Antimicrobial Susceptibilities of Isolates by YU, W.-L, WANG, D.-Y, LIN, C.-W, TSOU, M.-F

“…Burkholderia cepacia has emerged as a nosocomial pathogen, causing numerous outbreaks, particularly among cystic fibrosis (CF) patients. Reports of clinical…”
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PRODRUG-BASED TOPICAL DELIVERY: SIMULTANEOUS SKIN TRANSPORT AND BIOCONVERSION by YU, CHENG DER

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