Search Results - "CHEN Qianming"
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The function and mechanism of ferroptosis in cancer
Published in Apoptosis (London) (01-12-2020)“…Ferroptosis is a newly defined form of regulated cell death (RCD) characterized by iron overload, lipid reactive oxygen species (ROS) accumulation, and lipid…”
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TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
Published in Cancer research (Chicago, Ill.) (01-11-2017)“…Recent clinical successes of cancer immunotherapy necessitate the investigation of the interaction between malignant cells and the host immune system. However,…”
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The cytokine network involved in the host immune response to periodontitis
Published in International journal of oral science (05-11-2019)“…Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue in the periodontal region. Although dysbiosis of the local…”
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High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
Published in International journal of oral science (24-02-2020)“…It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell to cause the final…”
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TIMER2.0 for analysis of tumor-infiltrating immune cells
Published in Nucleic acids research (02-07-2020)“…Abstract Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor…”
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YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity
Published in Nature communications (19-03-2020)“…The Hippo TEAD-transcriptional regulators YAP1 and TAZ are central for cell renewal and cancer growth; however, the specific downstream gene networks involved…”
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7
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
Published in 国际口腔科学杂志(英文版) (24-02-2020)Get full text
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Crosstalk between the oral microbiota, mucosal immunity, and the epithelial barrier regulates oral mucosal disease pathogenesis
Published in Mucosal immunology (01-11-2021)“…Oral mucosal disease (OMD), which is also called soft tissue oral disease, is described as a series of disorders or conditions affecting the mucosa and soft…”
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Current status and future prospects of stomatology research
Published in Journal of Zhejiang University. B. Science (01-10-2023)“…Research in stomatology (dental medicine) continues to expand globally and is oriented towards solving clinical issues, focusing on clarifying the clinical…”
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The role of extracellular vesicles from different origin in the microenvironment of head and neck cancers
Published in Molecular cancer (06-04-2019)“…The proliferation and metastasis ability of tumors are mediate by the "mutual dialogue" between cells in the tumor microenvironment (TME). Extracellular…”
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Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication
Published in Pharmacology & therapeutics (Oxford) (01-09-2017)“…Malfunction of ubiquitin-proteasome system is tightly linked to tumor formation and tumor metastasis. Targeting the ubiquitin-pathway provides a new strategy…”
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Calcium phosphate cements for bone engineering and their biological properties
Published in Bone research (20-12-2017)“…Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their discovery in the 1980s, extensive research has been conducted to…”
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Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome
Published in Cancer research (Chicago, Ill.) (15-05-2021)“…( ) is a keystone periodontal pathogen associated with various digestive cancers. However, whether can promote colorectal cancer and the underlying mechanism…”
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14
Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging
Published in International journal of oral science (24-03-2021)“…Hyperglycemia induces chronic low-grade inflammation (inflammaging), which is a newly identified contributor to diabetes-related tissue lesions, including the…”
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Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis
Published in Nature communications (16-10-2017)“…Phosphofructokinase 1 (PFK1) plays a critical role in glycolysis; however, its role and regulation in tumorigenesis are not well understood. Here, we…”
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Updates on immunological mechanistic insights and targeting of the oral lichen planus microenvironment
Published in Frontiers in immunology (09-01-2023)“…Oral lichen planus (OLP) is a chronic immune inflammatory disease that is an oral potentially malignant disorder (OPMD), occurs in the oral mucosa and affects…”
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Shaoxia: a web-based interactive analysis platform for single cell RNA sequencing data
Published in BMC genomics (24-04-2024)“…In recent years, Single-cell RNA sequencing (scRNA-seq) is increasingly accessible to researchers of many fields. However, interpreting its data demands…”
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RACK1 promotes cancer progression by increasing the M2/M1 macrophage ratio via the NF‐κB pathway in oral squamous cell carcinoma
Published in Molecular oncology (01-04-2020)“…Receptor for activated C kinase 1 (RACK1) has been shown to promote oral squamous cell carcinoma (OSCC) progression, and RACK1 expression levels have been…”
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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Published in Cancer cell (16-06-2014)“…Mutually exclusive activating mutations in the GNAQ and GNA11 oncogenes, encoding heterotrimeric Gαq family members, have been identified in ∼83% and ∼6% of…”
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GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation
Published in Nature communications (22-09-2016)“…Osteoporosis is an age-related disease that affects millions of people. Growth differentiation factor 11 (GDF11) is a secreted member of the transforming…”
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