Search Results - "CHEN, WEICAI"
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USP18 promotes breast cancer growth by upregulating EGFR and activating the AKT/Skp2 pathway
Published in International journal of oncology (01-07-2018)“…Recent studies have suggested that ubiquitin-specific peptidase (USP)18 may act as an oncogene in various types of cancer. Although the role of USP18 in breast…”
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2
Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor
Published in Developmental cell (20-04-2020)“…Understanding of NAD+ metabolism provides many critical insights into health and diseases, yet highly sensitive and specific detection of NAD+ metabolism in…”
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3
Diet Evolution and Habitat Contraction of Giant Pandas via Stable Isotope Analysis
Published in Current biology (18-02-2019)“…The ancestral panda Ailurarctos lufengensis, excavated from the late Miocene, is thought to be carnivorous or omnivorous [1]. Today, giant pandas exclusively…”
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4
Genetic variation of the major histocompatibility complex (MHC class II B gene) in the threatened Hume's pheasant, Syrmaticus humiae
Published in PloS one (28-01-2015)“…Major histocompatibility complex (MHC) genes are the most polymorphic genes in vertebrates and encode molecules that play a crucial role in pathogen…”
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5
NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells
Published in Cell reports (Cambridge) (05-04-2022)“…The mechanism by which redox metabolism regulates the fates of acute myeloid leukemia (AML) cells remains largely unknown. Using a highly sensitive,…”
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6
siRNA-mediated suppression of collagen type iv alpha 2 (COL4A2) mRNA inhibits triple-negative breast cancer cell proliferation and migration
Published in Oncotarget (10-01-2017)“…Triple-negative breast cancer (TNBC) is more aggressive than other breast cancer subtypes. Collagen type IV alpha 2 (COL4A2), a major component of the basement…”
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7
Molecular Features of Triple Negative Breast Cancer: Microarray Evidence and Further Integrated Analysis
Published in PloS one (23-06-2015)“…Breast cancer is a heterogeneous disease usually including four molecular subtypes such as luminal A, luminal B, HER2-enriched, and triple-negative breast…”
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8
A new species of the genus Rana sensu lato Linnaeus, 1758 (Anura, Ranidae) from Wuyi Mountain, Fujian Province, China
Published in ZooKeys (26-10-2021)“…A new species of the frog genus Rana sensu lato from Wuyi Mountain, Fujian Province, China is described. Molecular phylogenetic analyses clustered the new…”
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9
Role of lncRNA Has2os in Skeletal Muscle Differentiation and Regeneration
Published in Cells (Basel, Switzerland) (01-11-2022)“…Long non-coding RNAs (lncRNAs) regulate a series of physiological processes and play an important role in development, metabolism and disease. Our previous…”
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10
Insights from ecological niche modeling on the taxonomic distinction and niche differentiation between the black‐spotted and red‐spotted tokay geckoes (Gekko gecko)
Published in Ecology and evolution (01-09-2014)“…The black‐spotted tokay and the red‐spotted tokay are morphologically distinct and have largely allopatric distributions. The black‐spotted tokay is…”
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11
Synthesis and characterization of polycation block copolymer Poly( l-lysine)- b-poly[N-(N′,N′-diisopropyl-aminoethyl)aspartamide] as potential pH responsive gene delivery system
Published in Polymer (Guilford) (24-01-2012)“…A series of Poly( l-lysine) m- b-poly[N-(N′,N′-diisopropylaminoethyl) aspartamide] n copolymers, abbreviated as PLL m- b-P[Asp(DIP)] n were designed and…”
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12
Population structure of the endangered Hume's pheasant (Syrmaticus humiae) inferred from a partial sequence of the mitochondrial DNA control region
Published in Biochemical systematics and ecology (01-12-2014)“…Genetic diversity plays a vital role in biological conservation, especially for those species under the threat of habitat loss and fragmentation. In this…”
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13
An improved ion-exchange/diffusion method for ~(15)N isotope tracing analysis of nitrate in surface waters from watersheds
Published in Journal of environmental sciences (China) (2010)“…An improved method,suitable for collecting nitrate from surface waters in the watershed for 15 N isotope tracing analysis,was developed on the basis of the…”
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14
Phylogeography of the large white-bellied rat Niviventer excelsior suggests the influence of Pleistocene glaciations in the Hengduan mountains
Published in Zoological science (01-06-2010)“…The Hengduan Mountains, situated in the southeastern Tibetan Plateau, have undergone dramatic geological and climatic changes over the Pleistocene epoch…”
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15
A new species of the genus Gracixalus (Amphibia: Anura: Rhacophoridae) from Southern Guangxi, China
Published in Zootaxa (18-02-2013)“…A new species of the genus Gracixalus is described from Nonggang National Nature Reserve, based on eleven specimens from evergreen karst forests in…”
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16
siRNA-Mediated Suppression of Synuclein γ Inhibits MDA-MB-231 Cell Migration and Proliferation by Downregulating the Phosphorylation of AKT and ERK
Published in Journal of breast cancer (01-09-2014)“…Synuclein-γ (SNCG), which was initially identified as breast cancer specific gene 1, is highly expressed in advanced breast cancers, but not in normal or…”
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17
Effects of long-term fertilization on soil carbon, nitrogen, phosphorus and rice yield
Published in Journal of plant nutrition (01-01-2013)“…□ Fertilization plays an important role in soil fertility and rice yield. A long-term (1990–2006) field experiment was conducted at a typical subtropical hilly…”
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18
An improved ion-exchange/diffusion method for 15N isotope tracing analysis of nitrate in surface waters from watersheds
Published in Journal of environmental sciences (China) (2010)“…An improved method, suitable for collecting nitrate from surface waters in the watershed for 15N isotope tracing analysis, was developed on the basis of the…”
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19
Co-Delivery of Doxorubicin and siRNA with Reduction and pH Dually Sensitive Nanocarrier for Synergistic Cancer Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2014)“…Drug resistance is the greatest challenge in clinical cancer chemotherapy. Co‐delivery of chemotherapeutic drugs and siRNA to tumor cells is a vital means to…”
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20
miR‐885‐5p plays an accomplice role in liver cancer by instigating TIGAR expression via targeting its promoter
Published in Biotechnology and applied biochemistry (01-09-2019)“…TIGAR (TP53‐induced glycolysis and apoptosis regulator) is a p53‐inducible gene and its expression resulted in controlling metabolism and protection from…”
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