Search Results - "CHEN, MENGJIE"
-
1
VIPER: variability-preserving imputation for accurate gene expression recovery in single-cell RNA sequencing studies
Published in Genome Biology (12-11-2018)“…We develop a method, VIPER, to impute the zero values in single-cell RNA sequencing studies to facilitate accurate transcriptome quantification at the…”
Get full text
Journal Article -
2
ROBUST COVARIANCE AND SCATTER MATRIX ESTIMATION UNDER HUBER’S CONTAMINATION MODEL
Published in The Annals of statistics (01-10-2018)“…Covariance matrix estimation is one of the most important problems in statistics. To accommodate the complexity of modern datasets, it is desired to have…”
Get full text
Journal Article -
3
Demystifying "drop-outs" in single-cell UMI data
Published in Genome Biology (06-08-2020)“…Many existing pipelines for scRNA-seq data apply pre-processing steps such as normalization or imputation to account for excessive zeros or "drop-outs." Here,…”
Get full text
Journal Article -
4
Thermally Driven Structure and Performance Evolution of Atomically Dispersed FeN4 Sites for Oxygen Reduction
Published in Angewandte Chemie (International ed.) (19-12-2019)“…FeN4 moieties embedded in partially graphitized carbon are the most efficient platinum group metal free active sites for the oxygen reduction reaction in…”
Get full text
Journal Article -
5
Nanocarbon/oxide composite catalysts for bifunctional oxygen reduction and evolution in reversible alkaline fuel cells: A mini review
Published in Journal of power sources (01-01-2018)“…A reversible fuel cell (RFC), which integrates a fuel cell with an electrolyzer, is similar to a rechargeable battery. This technology lies on high-performance…”
Get full text
Journal Article -
6
Precious metal-free approach to hydrogen electrocatalysis for energy conversion: From mechanism understanding to catalyst design
Published in Nano energy (01-12-2017)“…Hydrogen (H2) is the most promising green energy resources to replace conventional fossil fuels due to the high mass energy density and renewability. The…”
Get full text
Journal Article -
7
m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome
Published in Nature biotechnology (01-08-2022)“…Functional studies of the RNA N 6 -methyladenosine (m 6 A) modification have been limited by an inability to map individual m 6 A-modified sites in whole…”
Get full text
Journal Article -
8
A meta-analysis of the relationship between vaginal microecology, human papillomavirus infection and cervical intraepithelial neoplasia
Published in Infectious agents and cancer (26-10-2019)“…Microecology is an emerging discipline in recent years. The female reproductive tract is an important microecological region, and its microecological…”
Get full text
Journal Article -
9
Atomically dispersed manganese catalysts for oxygen reduction in proton-exchange membrane fuel cells
Published in Nature catalysis (29-10-2018)“…Platinum group metal (PGM)-free catalysts that are also iron free are highly desirable for the oxygen reduction reaction (ORR) in proton-exchange membrane fuel…”
Get full text
Journal Article -
10
REPIC: a database for exploring the N 6 -methyladenosine methylome
Published in Genome biology (28-04-2020)“…The REPIC (RNA EPItranscriptome Collection) database records about 10 million peaks called from publicly available m A-seq and MeRIP-seq data using our unified…”
Get full text
Journal Article -
11
Ternary PtIrNi Catalysts for Efficient Electrochemical Ammonia Oxidation
Published in ACS catalysis (03-04-2020)“…Ammonia (NH3) has proved to be an effective alternative to hydrogen in low-temperature fuel cells via its direct ammonia oxidation reaction (AOR). However, the…”
Get full text
Journal Article -
12
Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies
Published in Nature communications (27-03-2020)“…Differential expression (DE) analysis and gene set enrichment (GSE) analysis are commonly applied in single cell RNA sequencing (scRNA-seq) studies. Here, we…”
Get full text
Journal Article -
13
Immune infiltration and a ferroptosis-associated gene signature for predicting the prognosis of patients with endometrial cancer
Published in Aging (Albany, NY.) (30-06-2021)“…Ferroptosis, a form of programmed cell death induced by excess iron-dependent lipid peroxidation product accumulation, plays a critical role in cancer…”
Get full text
Journal Article -
14
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations
Published in Nature communications (26-05-2017)“…Approximately half of the world’s 500,000 new oesophageal squamous-cell carcinoma (ESCC) cases each year occur in China. Here, we show whole-genome sequencing…”
Get full text
Journal Article -
15
Integrins regulate stemness in solid tumor: an emerging therapeutic target
Published in Journal of hematology and oncology (29-10-2021)“…Abstract Integrins are the adhesion molecules and transmembrane receptors that consist of α and β subunits. After binding to extracellular matrix components,…”
Get full text
Journal Article -
16
Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC
Published in Molecular therapy. Nucleic acids (04-06-2021)“…Skeletal muscle development is a complex and highly orchestrated biological process mediated by a series of myogenesis regulatory factors. Numerous studies…”
Get full text
Journal Article -
17
Paclitaxel-loaded silk fibroin nanospheres
Published in Journal of biomedical materials research. Part A (01-01-2012)“…Silk fibroin is a very promising biomedical material because of its renewability, nontoxicity, biocompatibility, and biodegradability. On the basis of a simple…”
Get full text
Journal Article -
18
RADAR: differential analysis of MeRIP-seq data with a random effect model
Published in Genome Biology (23-12-2019)“…Epitranscriptome profiling using MeRIP-seq is a powerful technique for in vivo functional studies of reversible RNA modifications. We develop RADAR, a…”
Get full text
Journal Article -
19
The risk and latency evaluation of secondary primary malignancies of cervical cancer patients who received radiotherapy: A study based on the SEER database
Published in Frontiers in oncology (19-01-2023)“…To study the risk factors for the onset of secondary primary malignancies (SPM) and the latency between SPM and cervical cancer after radiotherapy. We selected…”
Get full text
Journal Article -
20
Case report: Brachial plexopathy caused by malignant peripheral nerve sheath tumor and review of the literature
Published in Frontiers in neurology (16-01-2023)“…Brachial plexopathy (BP) is easily misdiagnosed due to its complexity and varying clinical presentation. Malignant peripheral nerve sheath tumors (MPNST) can…”
Get full text
Journal Article