Search Results - "CHEN, Guanjie"
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“d‐Electron Complementation” Induced V‐Co Phosphide for Efficient Overall Water Splitting
Published in Advanced energy materials (01-10-2021)“…To generate “green hydrogen,” electrochemical water splitting is regarded as the most promising method, which requires highly efficient bifunctional…”
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2
Physiological mechanisms of ABA-induced salinity tolerance in leaves and roots of rice
Published in Scientific reports (17-05-2022)“…Abscisic acid (ABA) plays a crucial role in response to abiotic stress as important small molecules in regulating metabolism. This study aimed to evaluate the…”
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Transcriptomic and metabolomic analyses reveal that ABA increases the salt tolerance of rice significantly correlated with jasmonic acid biosynthesis and flavonoid biosynthesis
Published in Scientific reports (21-11-2023)“…Abscisic acid (ABA) has been shown to mitigate the deleterious effects of abiotic stresses and to regulate plant growth and development. Salinity is one of the…”
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Additive genetic effect of GCKR, G6PC2, and SLC30A8 variants on fasting glucose levels and risk of type 2 diabetes
Published in PloS one (03-06-2022)“…Impaired glucose tolerance is a major risk factor for type 2 diabetes (T2D) and several cardiometabolic disorders. To identify genetic loci underlying fasting…”
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Gastrodin Alleviates Cerebral Ischemic Damage in Mice by Improving Anti-oxidant and Anti-inflammation Activities and Inhibiting Apoptosis Pathway
Published in Neurochemical research (01-04-2015)“…Gastrodin (GAS), an active constituent of the Chinese herbal medicine Tianma, has anti-oxidant and anti-inflammation activities but its protective effect to…”
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6
The genomic landscape of African populations in health and disease
Published in Human molecular genetics (01-10-2017)“…A deeper appreciation of the complex architecture of African genomes is critical to the global effort to understand human history, biology and differential…”
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A genome-wide association study of hypertension and blood pressure in African Americans
Published in PLoS genetics (01-07-2009)“…The evidence for the existence of genetic susceptibility variants for the common form of hypertension ("essential hypertension") remains weak and inconsistent…”
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Preventing post-discharge suicides in psychiatric patients: insights from patients, lay healthcare supporters, and mental health professionals-a qualitative analysis
Published in BMC public health (02-01-2024)“…Discharged psychiatric patients are at higher risk of suicide due to various risk factors in their lives compared to the general population. However, specific…”
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9
FTO Genetic Variation and Association With Obesity in West Africans and African Americans
Published in Diabetes (New York, N.Y.) (01-06-2010)“…The FTO gene is one of the most consistently replicated loci for obesity. However, data from populations of African ancestry are limited. We evaluated genetic…”
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Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits
Published in Scientific reports (18-02-2021)“…Genome-wide association studies (GWAS) have identified thousands of genetic loci associated with cross-sectional blood pressure (BP) traits; however, GWAS…”
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11
Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations
Published in American journal of human genetics (05-09-2013)“…High blood pressure (BP) is more prevalent and contributes to more severe manifestations of cardiovascular disease (CVD) in African Americans than in any other…”
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12
Genetic risk scores for cardiometabolic traits in sub-Saharan African populations
Published in International journal of epidemiology (17-03-2021)“…Abstract Background There is growing support for the use of genetic risk scores (GRS) in routine clinical settings. Due to the limited diversity of current…”
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13
Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations
Published in PLoS genetics (12-05-2017)“…Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of…”
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14
Performance Evaluation of ERA5 Extreme Precipitation in the Yangtze River Delta, China
Published in Atmosphere (01-09-2022)“…Accurate extreme precipitation information is crucial for disaster risk management, social and economic development security, and climate change research…”
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Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians
Published in Genome medicine (05-03-2024)“…Type 2 diabetes (T2D) has reached epidemic proportions globally, including in Africa. However, molecular studies to understand the pathophysiology of T2D…”
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16
Exploring Cancer Incidence Trends by Age and Sex Among 14.14 Million Individuals in China From 2007 to 2021: Population-Based Study
Published in JMIR public health and surveillance (07-08-2024)“…Sex is a crucial factor in the development, progression, and treatment of cancer, making it vital to examine cancer incidence trends by sex for effective…”
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Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin
Published in American journal of human genetics (07-07-2016)“…Knowledge of the genetic basis of the type 2 diabetes (T2D)-related quantitative traits fasting glucose (FG) and insulin (FI) in African ancestry (AA)…”
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The Roles of IL-6, IL-10, and IL-1RA in Obesity and Insulin Resistance in African-Americans
Published in The journal of clinical endocrinology and metabolism (01-12-2011)“…Objective: The aim of the study was to investigate the associations between IL-1 receptor antagonist (IL-1RA), IL-6, IL-10, measures of obesity, and insulin…”
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A UGT1A1 variant is associated with serum total bilirubin levels, which are causal for hypertension in African-ancestry individuals
Published in Npj genomic medicine (11-06-2021)“…Serum bilirubin is associated with several clinical outcomes, including hypertension, type 2 diabetes (T2D), and drug metabolism. Here, we describe findings…”
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Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits
Published in Genome medicine (07-10-2021)“…A complex set of perturbations occur in cytokines and hormones in the etiopathogenesis of obesity and related cardiometabolic conditions such as type 2…”
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