Search Results - "CHAY, T"

Identification of distinct ChAT+ neurons and activity-dependent control of postnatal SVZ neurogenesis by Paez-Gonzalez, Patricia, Asrican, Brent, Rodriguez, Erica, Kuo, Chay T

“…This study describes a novel population of cholinergic neurons in the adult subependymal zone (SEZ) of mouse that modulates neural progenitor proliferation…”
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Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4 by Benner, Eric J., Luciano, Dominic, Jo, Rebecca, Abdi, Khadar, Paez-Gonzalez, Patricia, Sheng, Huaxin, Warner, David S., Liu, Chunlei, Eroglu, Cagla, Kuo, Chay T.

“…This paper identifies a specific population of subventricular-zone-generated astrocytes that increases in population density after cortical injury; these…”
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Uncovering inherent cellular plasticity of multiciliated ependyma leading to ventricular wall transformation and hydrocephalus by Abdi, Khadar, Lai, Chun-Hsiang, Paez-Gonzalez, Patricia, Lay, Mark, Pyun, Joon, Kuo, Chay T.

“…Specialized, differentiated cells often perform unique tasks that require them to maintain a stable phenotype. Multiciliated ependymal cells (ECs) are unique…”
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Neuronal Activity-Dependent Control of Postnatal Neurogenesis and Gliogenesis by Káradóttir, Ragnhildur T, Kuo, Chay T

“…The addition of new neurons and oligodendroglia in the postnatal and adult mammalian brain presents distinct forms of gray and white matter plasticity…”
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Astrocyte and Oligodendrocyte Responses From the Subventricular Zone After Injury by David-Bercholz, Jennifer, Kuo, Chay T, Deneen, Benjamin

“…Under normal conditions, neural stem cells (NSCs or B cells) in the adult subventricular zone (SVZ) give rise to amplifying neural progenitor cells (NPCs or C…”
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Cortical regulation of neurogenesis and cell proliferation in the ventral subventricular zone by Naffaa, Moawiah M., Khan, Rehan R., Kuo, Chay T., Yin, Henry H.

“…Neurogenesis and differentiation of neural stem cells (NSCs) are controlled by cell-intrinsic molecular pathways that interact with extrinsic signaling cues…”
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Laminating the mammalian cortex during development: cell polarity protein function and Hippo signaling by Abdi, Khadar, Kuo, Chay T

“…During mammalian brain development, radial glial progenitors balance between proliferation and differentiation to generate the laminated cortical layers in a…”
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Low excitatory innervation balances high intrinsic excitability of immature dentate neurons by Dieni, Cristina V., Panichi, Roberto, Aimone, James B., Kuo, Chay T., Wadiche, Jacques I., Overstreet-Wadiche, Linda

“…Persistent neurogenesis in the dentate gyrus produces immature neurons with high intrinsic excitability and low levels of inhibition that are predicted to be…”
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Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory by Pan, Yung-Wei, Chan, Guy C K, Kuo, Chay T, Storm, Daniel R, Xia, Zhengui

“…Although there is evidence suggesting that adult neurogenesis may contribute to hippocampus-dependent memory, signaling mechanisms responsible for adult…”
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Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function by Dumm, Rebekah E., Fiege, Jessica K., Waring, Barbara M., Kuo, Chay T., Langlois, Ryan A., Heaton, Nicholas S.

“…Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown…”
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Drosophila Neuroblast Asymmetric Cell Division: Recent Advances and Implications for Stem Cell Biology by Yu, Fengwei, Kuo, Chay T., Jan, Yuh Nung

“…Asymmetric cell division is an evolutionarily conserved mechanism widely used to generate cellular diversity during development. Drosophila neuroblasts have…”
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Identification of E2/E3 Ubiquitinating Enzymes and Caspase Activity Regulating Drosophila Sensory Neuron Dendrite Pruning by Kuo, Chay T., Zhu, Sijun, Younger, Susan, Jan, Lily Y., Jan, Yuh Nung

“…Ubiquitin-proteasome system (UPS) is a multistep protein degradation machinery implicated in many diseases. In the nervous system, UPS regulates remodeling and…”
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EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation by Abdi, Khadar, Neves, Gabriel, Pyun, Joon, Kiziltug, Emre, Ahrens, Angelica, Kuo, Chay T.

“…Specialized microenvironments, called niches, control adult stem cell proliferation and differentiation. The brain lateral ventricular (LV) neurogenic niche is…”
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Nuclear factor I-A regulates diverse reactive astrocyte responses after CNS injury by Laug, Dylan, Huang, Teng-Wei, Huerta, Navish A Bosquez, Huang, Anna Yu-Szu, Sardar, Debosmita, Ortiz-Guzman, Joshua, Carlson, Jeffrey C, Arenkiel, Benjamin R, Kuo, Chay T, Mohila, Carrie A, Glasgow, Stacey M, Lee, Hyun Kyoung, Deneen, Benjamin

“…Reactive astrocytes are associated with every form of neurological injury. Despite their ubiquity, the molecular mechanisms controlling their production and…”
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Inducible and targeted deletion of the ERK5 MAP kinase in adult neurogenic regions impairs adult neurogenesis in the olfactory bulb and several forms of olfactory behavior by Pan, Yung-Wei, Kuo, Chay T, Storm, Daniel R, Xia, Zhengui

“…Although adult-born neurons in the subventricular zone (SVZ) and olfactory bulb (OB) have been extensively characterized at the cellular level, their…”
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Postnatal Deletion of Numb/Numblike Reveals Repair and Remodeling Capacity in the Subventricular Neurogenic Niche by Kuo, Chay T., Mirzadeh, Zaman, Soriano-Navarro, Mario, Rašin, Mladen, Wang, Denan, Shen, Jie, Šestan, Nenad, Garcia-Verdugo, Jose, Alvarez-Buylla, Arturo, Jan, Lily Y., Jan, Yuh-Nung

“…Neural stem cells are retained in the postnatal subventricular zone (SVZ), a specialized neurogenic niche with unique cytoarchitecture and cell-cell contacts…”
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Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling by Kuo, C.T, Jan, L.Y, Jan, Y.N

“…During neuronal maturation, dendrites develop from immature neurites into mature arbors. In response to changes in the environment, dendrites from certain…”
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Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury by Chaboub, Lesley S, Manalo, Jeanne M, Lee, Hyun Kyoung, Glasgow, Stacey M, Chen, Fengju, Kawasaki, Yoshihiro, Akiyama, Tetsu, Kuo, Chay T, Creighton, Chad J, Mohila, Carrie A, Deneen, Benjamin

“…Lineage development is a stepwise process, governed by stage-specific regulatory factors and associated markers. Astrocytes are one of the principle cell types…”
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Inducible and Conditional Deletion of Extracellular Signal-regulated Kinase 5 Disrupts Adult Hippocampal Neurogenesis by Pan, Yung-Wei, Zou, Junhui, Wang, Wenbin, Sakagami, Hiroyuki, Garelick, Michael G., Abel, Glen, Kuo, Chay T., Storm, Daniel R., Xia, Zhengui

“…Recent studies have led to the exciting idea that adult-born neurons in the dentate gyrus of the hippocampus may play a role in hippocampus-dependent memory…”
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Ank3-Dependent SVZ Niche Assembly Is Required for the Continued Production of New Neurons by Paez-Gonzalez, Patricia, Abdi, Khadar, Luciano, Dominic, Liu, Yan, Soriano-Navarro, Mario, Rawlins, Emma, Bennett, Vann, Garcia-Verdugo, Jose Manuel, Kuo, Chay T.

“…The rodent subventricular/subependymal zone (SVZ/SEZ) houses neural stem cells (NSCs) that generate olfactory bulb interneurons. It is unclear how the SVZ…”
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