Search Results - "CHAVENT, Matthieu"
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Game on, science - how video game technology may help biologists tackle visualization challenges
Published in PloS one (06-03-2013)“…The video games industry develops ever more advanced technologies to improve rendering, image quality, ergonomics and user experience of their creations…”
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The conical shape of DIM lipids promotes Mycobacterium tuberculosis infection of macrophages
Published in Proceedings of the National Academy of Sciences - PNAS (17-12-2019)“…Phthiocerol dimycocerosate (DIM) is a major virulence factor of the pathogen Mycobacterium tuberculosis (Mtb). While this lipid promotes the entry of Mtb into…”
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Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons
Published in Cell (23-01-2020)“…Teneurins are ancient metazoan cell adhesion receptors that control brain development and neuronal wiring in higher animals. The extracellular C terminus binds…”
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Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes
Published in Scientific reports (30-11-2017)“…Cell membranes are crowded and complex environments. To investigate the effect of protein-lipid interactions on dynamic organization in mammalian cell…”
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Supramolecular organisation and dynamics of mannosylated phosphatidylinositol lipids in the mycobacterial plasma membrane
Published in Biophysical journal (10-02-2023)Get full text
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Membrane stiffness is modified by integral membrane proteins
Published in Soft matter (01-01-2016)“…The ease with which a cell membrane can bend and deform is important for a wide range of biological functions. Peripheral proteins that induce curvature in…”
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How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins
Published in Nature communications (20-07-2018)“…The spatiotemporal organisation of membranes is often characterised by the formation of large protein clusters. In Escherichia coli , outer membrane protein…”
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Bendix: intuitive helix geometry analysis and abstraction
Published in Bioinformatics (15-08-2012)“…The flexibility of α-helices is important for membrane protein function and calls for better visualization and analysis. Software is presented that quantifies…”
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Lipid-Loving ANTs: Molecular Simulations of Cardiolipin Interactions and the Organization of the Adenine Nucleotide Translocase in Model Mitochondrial Membranes
Published in Biochemistry (Easton) (15-11-2016)“…The exchange of ADP and ATP across the inner mitochondrial membrane is a fundamental cellular process. This exchange is facilitated by the adenine nucleotide…”
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Super-complexes of adhesion GPCRs and neural guidance receptors
Published in Nature communications (19-04-2016)“…Latrophilin adhesion-GPCRs (Lphn1–3 or ADGRL1–3) and Unc5 cell guidance receptors (Unc5A–D) interact with FLRT proteins (FLRT1–3), thereby promoting cell…”
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Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-2022)“…During spermatogenesis, spermatogonia undergo a series of mitotic and meiotic divisions on their path to spermatozoa. To achieve this, a succession of…”
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MDverse, shedding light on the dark matter of molecular dynamics simulations
Published in eLife (30-08-2024)“…The rise of open science and the absence of a global dedicated data repository for molecular dynamics (MD) simulations has led to the accumulation of MD files…”
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Structures of the EphA2 Receptor at the Membrane: Role of Lipid Interactions
Published in Structure (London) (02-02-2016)“…Ephs are transmembrane receptors that mediate cell-cell signaling. The N-terminal ectodomain binds ligands and enables receptor clustering, which activates the…”
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Design – a new way to look at old molecules
Published in Journal of integrative bioinformatics (01-07-2022)“…We discuss how design enriches molecular science, particularly structural biology and bioinformatics. We present two use cases, one in academic practice and…”
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Molecular Modeling and Simulation of the Mycobacterial Cell Envelope: From Individual Components to Cell Envelope Assemblies
Published in The journal of physical chemistry. B (28-12-2023)“…Unlike typical Gram-positive bacteria, the cell envelope of mycobacteria is unique and composed of a mycobacterial outer membrane, also known as the…”
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Visualizing protein structures - tools and trends
Published in Biochemical Society transactions (29-04-2020)“…Molecular visualization is fundamental in the current scientific literature, textbooks and dissemination materials. It provides an essential support for…”
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Molecular Simulations of Gram-Negative Bacterial Membranes: A Vignette of Some Recent Successes
Published in Biophysical journal (04-08-2015)“…In the following review we use recent examples from the literature to discuss progress in the area of atomistic and coarse-grained molecular dynamics…”
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Molecular dynamics simulations of membrane proteins and their interactions: from nanoscale to mesoscale
Published in Current opinion in structural biology (01-10-2016)“…[Display omitted] •Simulations provide a computational tool to probe membrane structure and dynamics.•Simulations can successfully predict lipid binding sites…”
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Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor Smoothened
Published in Structure (London) (05-03-2019)“…Transduction of Hedgehog signals across the plasma membrane is facilitated by the class F G-protein-coupled-receptor (GPCR) Smoothened (SMO). Recent studies…”
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Combining MD Simulations and 31P NMR Spectroscopy to Decipher Lamellar to Hexagonal Phase Transition Promoted by Diverse Lipid Types
Published in Biophysical journal (02-02-2018)Get full text
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