Search Results - "CHAUHAN, Prem M. S"

Synthesis of new 4-aminoquinolines and quinoline–acridine hybrids as antimalarial agents by Kumar, Ashok, Srivastava, Kumkum, Raja Kumar, S., Puri, S.K., Chauhan, Prem M.S.

“…New side chain modified 4-aminoquinolines and quinoline–acridine hybrids were synthesized and screened in vitro against NF 54 strain of Plasmodium falciparum…”
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Bis and tris indole alkaloids from marine organisms: new leads for drug discovery by Gupta, Leena, Talwar, Archna, Chauhan, Prem M S

“…The marine organisms are a rich source of varied natural products with unique functionality. Marine natural products chemistry has undergone an explosive…”
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Cyanuric Chloride Catalyzed Mild Protocol for Synthesis of Biologically Active Dihydro/Spiro Quinazolinones and Quinazolinone-glycoconjugates by Sharma, Moni, Pandey, Shashi, Chauhan, Kuldeep, Sharma, Deepty, Kumar, Brijesh, Chauhan, Prem M. S

“…We have developed an efficient cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT) catalyzed approach for the synthesis of 2,3-dihydroquinazolin-4­(1H)-one…”
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Design and Synthesis of a New Class of 4-Aminoquinolinyl- and 9-Anilinoacridinyl Schiff Base Hydrazones as Potent Antimalarial Agents by Sharma, Moni, Chauhan, Kuldeep, Srivastava, Rajeev K., Singh, Shiv V., Srivastava, Kumkum, Saxena, Jitendra K., Puri, Sunil K., Chauhan, Prem M. S.

“…A series of novel 4‐aminoquinolinyl and 9‐anilinoacridinyl Schiff base hydrazones have been synthesized and evaluated for their antimalarial activity. All…”
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Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents by Kumar, Ashok, Srivastava, Kumkum, Raja Kumar, S., Puri, S.K., Chauhan, Prem M.S.

“…A series of new class of hybrid 4-aminoquinoline triazines were synthesized and screened against CQ sensitive strain 3D7 of P. falciparum in an in vitro model…”
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Synthesis of oxalamide and triazine derivatives as a novel class of hybrid 4-aminoquinoline with potent antiplasmodial activity by Sunduru, Naresh, Sharma, Moni, Srivastava, Kumkum, Rajakumar, S., Puri, S.K., Saxena, J.K., Chauhan, Prem M.S.

“…In search of novel 4-aminoquinolines to counteract the problem of resistance, side chain incorporated oxalamide and triazine derivatives were synthesized and…”
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Synthesis of 9-anilinoacridine triazines as new class of hybrid antimalarial agents by Kumar, Ashok, Srivastava, Kumkum, Raja Kumar, S., Puri, S.K., Chauhan, Prem M.S.

“…A series of new class of hybrid 9-anilinoacridine triazines were synthesized and screened in vitro for their antimalarial activity against CQ-sensitive 3D7…”
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Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges by Sharma, Moni, Chauhan, Prem M S

“…Infectious diseases caused by parasites continue to take a massive toll on human health in the poor regions of the world. Filling the anti-infective…”
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Discovery of a New Class of Natural Product-Inspired Quinazolinone Hybrid as Potent Antileishmanial agents by Sharma, Moni, Chauhan, Kuldeep, Shivahare, Rahul, Vishwakarma, Preeti, Suthar, Manish K, Sharma, Abhisheak, Gupta, Suman, Saxena, Jitendra K, Lal, Jawahar, Chandra, Preeti, Kumar, Brijesh, Chauhan, Prem M. S

“…The high potential of quinazolinone containing natural products and their derivatives in medicinal chemistry led us to discover four novel series of 53…”
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A Ligand-Free Pd-Catalyzed Cascade Reaction: An Access to the Highly Diverse Isoquinolin-1(2H)-one Derivatives via Isocyanide and Ugi-MCR Synthesized Amide Precursors by Tyagi, Vikas, Khan, Shahnawaz, Giri, Archana, Gauniyal, Harsh M, Sridhar, B, Chauhan, Prem M. S

“…A novel ligand-free palladium-catalyzed cascade reaction for the synthesis of highly diverse isoquinolin-1(2H)-one derivatives from isocyanide and amide…”
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Synthesis and biological evaluation of indolyl glyoxylamides as a new class of antileishmanial agents by Chauhan, Shikha S., Gupta, Leena, Mittal, Monika, Vishwakarma, Preeti, Gupta, Suman, Chauhan, Prem M.S.

“…A series of indolylglyoxylamide derivatives have been synthesized and screened for their in vitro antileishmanial activity against Leishmania donovani. A…”
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Skeletal Diverse Synthesis of N-Fused Polycyclic Heterocycles via the Sequence of Ugi-Type MCR and CuI-Catalyzed Coupling/Tandem Pictet–Spengler Reaction by Tyagi, Vikas, Khan, Shahnawaz, Bajpai, Vikas, Gauniyal, Harsh M, Kumar, Brijesh, Chauhan, Prem M. S

“…Several diversity-oriented syntheses of N-fused polycyclic heterocycles have been demonstrated but most of them are based on point diversity within the same…”
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Synthesis of Perspicamide A and Related Diverse Analogues: Their Bioevaluation as Potent Antileishmanial Agents by Pandey, Anand Kumar, Sharma, Rashmi, Shivahare, Rahul, Arora, Ashish, Rastogi, Neeraj, Gupta, Suman, Chauhan, Prem M. S

“…The first protocol for the synthesis of perspicamide A and related diverse analogues has been developed from economical and readily available starting…”
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Synthesis and biological evaluation of new [1,2,4]triazino[5,6- b]indol-3-ylthio-1,3,5-triazines and [1,2,4]triazino[5,6- b]indol-3-ylthio-pyrimidines against Leishmania donovani by Gupta, Leena, Sunduru, Naresh, Verma, Aditya, Srivastava, Saumya, Gupta, Suman, Goyal, Neena, Chauhan, Prem M.S.

“…A series of [1,2,4]triazino[5,6- b]indol-3-ylthio-1,3,5-triazines and [1,2,4]triazino[5,6- b]indol-3-ylthio-pyrimidines were synthesized and screened for their…”
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Discovery of Novel Antileishmanial Agents in an Attempt to Synthesize Pentamidine−Aplysinopsin Hybrid Molecule by Porwal, Sharad, Chauhan, Shikha S, Chauhan, Prem M. S, Shakya, Nishi, Verma, Aditya, Gupta, Suman

“…In an attempt to synthesize pentamidine−aplysinopsin hybrid molecule 25, a lead molecule 8 (containing Z-configured aplysinopsin moiety) was identified for…”
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Synthesis of novel β-carboline based chalcones with high cytotoxic activity against breast cancer cells by Chauhan, Shikha S, Singh, Anup K, Meena, Sanjeev, Lohani, Minaxi, Singh, Akhilesh, Arya, Rakesh K, Cheruvu, Srikanth H, Sarkar, Jayanta, Gayen, Jiaur R, Datta, Dipak, Chauhan, Prem M S

“…A series of novel β-carboline based chalcones was synthesized and evaluated for their cytotoxic activity against a panel of human cancer cell lines. Among them…”
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Discovery of new 1,3,5-triazine scaffolds with potent activity against Mycobacterium tuberculosis H37Rv by Sunduru, Naresh, Gupta, Leena, Chaturvedi, Vinita, Dwivedi, Richa, Sinha, Sudhir, Chauhan, Prem M.S.

“…A series of eighty one 2,4,6-trisubstituted-1,3,5-triazines were synthesized and evaluated in vitro for the growth inhibition of Mycobacterium tuberculosis…”
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4-Anilinoquinoline triazines: A novel class of hybrid antimalarial agents by Kumar, Ashok, Srivastava, Kumkum, Raja Kumar, S., Siddiqi, M.I., Puri, Sunil K., Sexana, Jitendra K., Chauhan, Prem M.S.

“…A novel class of hybrid 4-anilinoquinoline triazines have been synthesized and evaluated in vitro for their antimalarial activity against CQ-sensitive 3D7…”
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Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials by Sunduru, Naresh, Srivastava, Kumkum, Rajakumar, S., Puri, S.K., Saxena, J.K., Chauhan, Prem M.S.

“…New prototypes of thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline were synthesized and screened for their antimalarial…”
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Synthesis and cytotoxicity evaluation of (tetrahydro-β-carboline)-1,3,5-triazine hybrids as anticancer agents by Kumar, Ravi, Gupta, Leena, Pal, Pooja, Khan, Shahnawaz, Singh, Neetu, Katiyar, Sanjay Babu, Meena, Sanjeev, Sarkar, Jayanta, Sinha, Sudhir, Kanaujiya, Jitendra Kumar, Lochab, Savita, Trivedi, Arun Kumar, Chauhan, Prem M.S.

“…A series of tetrahydro-β-carbolines and 1,3,5-triazine hybrids have been synthesized and evaluated for their cytotoxicity against a panel of eight human cancer…”
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