Search Results - "CHAUCHEREAU, Anne"
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Enzalutamide response in a panel of prostate cancer cell lines reveals a role for glucocorticoid receptor in enzalutamide resistant disease
Published in Scientific reports (10-12-2020)“…Representative in vitro model systems that accurately model response to therapy and allow the identification of new targets are important for improving our…”
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Abstract 892: ROCK dependent signalling pathways contribution to collective invasion of colorectal carcinoma
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Metastatic progression of cancer, which is responsible for 90% of patients death, results from tumor cells dissemination out of the primary tumor…”
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3
A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
Published in Cancer research (Chicago, Ill.) (2013)“…Galectins, a family of glycan-binding proteins, influence tumor progression by modulating interactions between tumor, endothelial, stromal, and immune cells…”
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4
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer
Published in Nature communications (13-08-2022)“…Lineage plasticity of prostate cancer is associated with resistance to androgen receptor (AR) pathway inhibition (ARPI) and supported by a reactive tumor…”
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Stable and high expression of Galectin-8 tightly controls metastatic progression of prostate cancer
Published in Oncotarget (04-07-2017)“…Two decades ago, Galectin-8 was described as a prostate carcinoma biomarker since it is only expressed in the neoplastic prostate, but not in the healthy…”
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Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis
Published in EMBO molecular medicine (01-07-2016)“…Clusterin (CLU) is a stress‐activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates…”
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Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making
Published in PLoS genetics (06-06-2016)“…Understanding the medical effect of an ever-growing number of human variants detected is a long term challenge in genetic counseling. Functional assays, based…”
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E2F3 Is a Mediator of DNA Damage-Induced Apoptosis
Published in Molecular and Cellular Biology (01-01-2010)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome
Published in Journal for immunotherapy of cancer (08-12-2020)“…BackgroundProstate cancer (PCa) is a major health problem worldwide. Taxol derivatives-based chemotherapies or immunotherapies are usually proposed depending…”
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The IGR-CaP1 Xenograft Model Recapitulates Mixed Osteolytic/Blastic Bone Lesions Observed in Metastatic Prostate Cancer
Published in Neoplasia (New York, N.Y.) (01-05-2012)“…Abstract Bone metastases have a devastating impact on quality of life and bone pain in patients with prostate cancer and decrease survival. Animal models are…”
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Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1
Published in The Journal of biological chemistry (04-04-2003)“…SUMO-1 (small ubiquitin-like modifier) conjugation regulates the subcellular localization, stability, and activity of a variety of proteins. We show here that…”
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HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF
Published in Oncogene (18-11-2004)“…PLZF, the promyelocytic leukaemia zinc-finger protein, is a transcriptional repressor essential to development. In some acute leukaemias, a chromosomal…”
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Differential Recruitment of p160 Coactivators by Glucocorticoid Receptor between Schwann Cells and Astrocytes
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2006)“…In the nervous system, glucocorticoids can exert beneficial or noxious effects, depending on their concentration and the duration of hormonal stimulation. They…”
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JAB1 Interacts with Both the Progesterone Receptor and SRC-1
Published in The Journal of biological chemistry (24-03-2000)“…JAB1 (Jun activation domain-binding protein-1) has previously been described as a coactivator of AP1 transcription factor. We show here, by yeast and mammalian…”
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Selective Recruitment of p160 Coactivators on Glucocorticoid-Regulated Promoters in Schwann Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2004)“…In the nervous system, glucocorticoid hormones play a major role during development and throughout life. We studied the mechanisms of action of the…”
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Involvement of β-Catenin and Unusual Behavior of CBP and p300 in Glucocorticosteroid Signaling in Schwann Cells
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2005)“…In the nervous system, glucocorticosteroid hormones play a major role during development and adult life. Myelin-forming cells are among the targets of…”
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Subcellular Localization and Mechanisms of Nucleocytoplasmic Trafficking of Steroid Receptor Coactivator-1
Published in The Journal of biological chemistry (22-08-2003)“…Steroid hormone receptors are ligand-stimulated transcription factors that modulate gene transcription by recruiting coregulators to gene promoters…”
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Experimental models for the development of new medical treatments in prostate cancer
Published in European journal of cancer (1990) (01-09-2011)Get full text
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A vitamin D‐based strategy overcomes chemoresistance in prostate cancer
Published in British journal of pharmacology (01-11-2024)“…Background and purpose Castration‐resistant prostate cancer (CRPC) is a common male malignancy that requires new therapeutic strategies due to acquired…”
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Abstract 3960: Low doses of Docetaxel in combination with anti-prostate cancer immunotherapy lead to complete tumor-free outcome through Galectin-3 silencing
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Based on animal model results and the analysis of clinical data from metastatic and castration resistant prostate cancer (mCRPC) patients, we were…”
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