Search Results - "CHATEAUNEUF, Anne"
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1
Super-refractory status epilepticus: epidemiology, early predictors, and outcomes
Published in Intensive care medicine (01-10-2017)Get full text
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2
Cardiac Arrest in Patients Managed for Convulsive Status Epilepticus: Characteristics, Predictors, and Outcome
Published in Critical care medicine (01-08-2018)“…OBJECTIVES:Cardiac arrest is a catastrophic event that may arise during the management of convulsive status epilepticus. We aimed to report the clinical…”
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3
Comparison of etomidate and sodium thiopental for induction during rapid sequence intubation in convulsive status epilepticus: A retrospective single-center study
Published in Seizure (London, England) (01-10-2018)“…•Etomidate and sodium thiopental can be used for rapid sequence intubation in convulsive status epilepticus.•Seizure and/or status epilepticus recurrence…”
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4
Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP
Published in Journal of allergy and clinical immunology (01-12-2001)“…Background: PGD2 is the major prostanoid released by mast cells during an allergic response. Its role in the allergic response, however, remains unclear…”
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5
Potent and selective 5-LO inhibitor bearing benzothiophene pharmacophore: Discovery of MK-5286
Published in Bioorganic & medicinal chemistry letters (15-12-2010)“…The strategy and SAR studies that led to the discovery of a novel potent and orally available 5-lipoxygenase (5-LO) inhibitor 3-(4-fluorophenyl)-6-({4-[(1…”
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6
A Role for Ultraviolet A in solar Mutagenesis
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-1995)“…It is well established that exposure to solar UVB (290-320 nm) gives rise to mutations in oncogenes and tumor suppressor genes that initiate the molecular…”
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7
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor
Published in Bioorganic & medicinal chemistry letters (24-03-2003)“…Analogues of PGE(2) wherein the hydroxycyclopentanone ring has been replaced by a lactam have been prepared and evaluated as ligands for the EP(4) receptor. An…”
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8
The Discovery of Setileuton, a Potent and Selective 5-Lipoxygenase Inhibitor
Published in ACS medicinal chemistry letters (08-07-2010)“…The discovery of novel and selective inhibitors of human 5-lipoxygenase (5-LO) is described. These compounds are potent, orally bioavailable, and active at…”
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9
Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2
Published in British journal of pharmacology (01-12-2002)“…The recombinant human prostaglandin D2 (PGD2) receptor, hCRTH2, has been expressed in HEK293(EBNA) and characterized with respect to radioligand binding and…”
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10
Identification of a GABAB Receptor Subunit, gb2, Required for Functional GABAB Receptor Activity
Published in The Journal of biological chemistry (19-03-1999)“…G protein-coupled receptors are commonly thought to bind their cognate ligands and elicit functional responses primarily as monomeric receptors. In studying…”
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11
Molecular pharmacology of the human prostaglandin D 2 receptor, CRTH2
Published in British journal of pharmacology (01-12-2002)“…The recombinant human prostaglandin D 2 (PGD 2 ) receptor, hCRTH2, has been expressed in HEK293(EBNA) and characterized with respect to radioligand binding and…”
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12
Characterization of the human cysteinyl leukotriene CysLT1 receptor
Published in Nature (London) (24-06-1999)“…The cysteinyl leukotrienes-leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE4)-are important mediators of human bronchial asthma…”
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13
Molecular Characterization and Expression of Cloned Human Galanin Receptors GALR2 and GALR3
Published in Journal of neurochemistry (01-12-1998)“…: Galanin is a 29‐ or 30‐amino acid peptide with wide‐ranging effects on hormone release, feeding behavior, smooth muscle contractility, and somatosensory…”
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14
2,3-Diarylthiophenes as selective EP1 receptor antagonists
Published in Bioorganic & medicinal chemistry letters (15-02-2005)“…The synthesis and the EP(1) receptor binding affinity of 2,3-diarylthiophene derivatives are described. The evaluation of the structure-activity relationship…”
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15
Structure-activity relationship of triaryl propionic acid analogues on the human EP3 prostanoid receptor
Published in Bioorganic & medicinal chemistry letters (03-11-2003)“…Potent and selective ligands for the human EP3 prostanoid receptor are described. Triaryl compounds bearing an ortho-substituted propionic acid moiety were…”
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16
Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor
Published in The Journal of pharmacology and experimental therapeutics (01-05-2000)“…Direct evidence is lacking to show whether the gamma-aminobutyric acid (GABA)(B) gb1-gb2 heterodimer is the signaling form of the receptor. In this study, we…”
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2,3-Diarylthiophenes as selective EP 1 receptor antagonists
Published in Bioorganic & medicinal chemistry letters (2005)“…The synthesis and biological activity of a novel series of EP 1 receptor antagonists is reported. SAR studies in this series led to the identification of…”
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18
Structure–activity relationship of triaryl propionic acid analogues on the human EP 3 prostanoid receptor
Published in Bioorganic & medicinal chemistry letters (01-11-2003)Get full text
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19
Discovery of a potent and selective agonist of the prostaglandin EP 4 receptor
Published in Bioorganic & medicinal chemistry letters (2003)“…Analogues of PGE 2 wherein the hydroxycyclopentanone ring has been replaced by a lactam have been prepared and evaluated as ligands for the EP 4 receptor. An…”
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20
Cloning of a Novel G-Protein-Coupled Receptor GPR 51 Resembling GABA Receptors Expressed Predominantly in Nervous Tissues and Mapped Proximal to the Hereditary Sensory Neuropathy Type 1 Locus on Chromosome 9
Published in Genomics (San Diego, Calif.) (15-03-1999)“…Query of the expressed sequence tag database with the rat metabotropic GABA sub(B)R1A receptor amino acid sequence using the TFASTA algorithm revealed two…”
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